简介:摘要:本文基于表观遗传经济动态能力理论,构建基于EED- TOE-SEM理论模型,分析外贸企业数字化转型机制, 基于表观遗传学的经济隐喻,将外贸企业适应数字经济环境并转型的过程,与生物细胞适应环境、改变表型并遗传的过程相对应起来,构建广东外贸企业数字经济转型的典型模式SEM理论模型,并为进一步深入讨论和分析数字经济对广东外贸企业应对疫情路径选择的可行性进行SEM理论模型构建的模型设计。
简介:AbstractIntroduction:Verrucous carcinoma is a rare variant of squamous cell carcinoma. It generally grows exogenously and bone erosion is rare. Here we present a case of verrucous carcinoma on the foot with toe absence.Case presentation:A 64-year-old man presented with a 6-year history of a slowly growing exogenous hyperkeratotic verrucous lesion on the right fifth toe, which had been absent for 1 year. Before the lesion appeared, he had undergone nail extraction on this toe. The culture of fungi and mycobacteria were negative. Three-dimensional computed tomography showed that the fifth toe of the right foot was absent. Histopathological examination showed that the lesion was exogenous and verrucous and exhibited moderate keratinocyte hyperplasia. Combined with clinical manifestation and histopathological examination, verrucous carcinoma is suggested. The lesion was surgically excised, and the patient was followed up for more than 6 months without recurrence.Discussion:Verrucous carcinoma is an exophytic tumor with verrucous growth at the beginning, which can invade deep tissues and even cause limb mutilation. When encountering a patient with a wart-like plaque on the foot that responds poorly to conventional treatments, clinicians should maintain a high degree of clinical vigilance and a low threshold for biopsy.Conclusion:We observed a rare outcome of toe absence associated with verrucous carcinoma. Therefore, early diagnosis of verrucous carcinoma is very important. Surgical excision is an effective treatment at present. Extensive resection is usually required to avoid recurrence.
简介:摘要:本文主要基于表观遗传动态经济学EED理论,在EED- TOE模型下分析EED 视角下外贸企业数字化高质量发展模式机理,并提出外贸企业数字化高质量发展模式路径建议。
简介:Background:Numerousstudiesabouttheinteractionbetweenfootwear(andbarefoot)andkinematicandkineticoutcomeshavebeenpublishedoverthelastfewyears.Recentstudieshoweverleadtotheconclusionthattheassumedinteractionsdependmainlyonthesubjects'experienceofbarefoot(BF)walking/running,thepreferredrunningstrikepattern,thespeed,thehardnessofthesurface,thethicknessofthemidsolematerial,andtherunners'levelofability.Theaimofthepresentstudywastoinvestigatelowerlegkinematicso\'BFrunningandrunninginminimalrunningshoes(MRS)toassesscomparabilityofBFkinematicsinbothconditions.Tosystematicallycomparebothconditionswemonitoredtheinfluencingvariablesdescribedaboveinourmeasurementsetup.WehypothesizedthatrunninginMRSdoesnotalterlowerlegkinematicscomparedtoBFrunning.Methods:Thirty-sevensubjects,injury-freeandactiveinsports,ranBFonanEVAfoamrunway,andalsoranshodwearingNikeFree3.0onatartanindoortrack.Lower-leg3Dkinematicswasmeasuredtoquantifyrearfootandanklemovements.SkinmarkerswereusedinbothshodandBFrunning.Results:Allrunnersrevealedrearfootstrikepatternwhenrunningbarefoot.DifferencesbetweenBFandMRSrunningoccurredparticularlyduringtheinitialstancephaseofrunning,bothinthesagittalandthefrontalplanes.BFrunningrevealedaflatterfootplacement,amoreplantarflexedanklejointandlessinvertedrearfootattouchdowncomparedtoMRSrunning.Conclusion:BFrunningdoesnotchangethelandingautomaticallytoforefootrunning,especiallyafterasystematicexclusionofsurfaceandotherinfluencingfactors.TheNikeFree3.0mimicssomeBFfeatures.Nevertheless,changesindesignoftheNikeFreeshouldbeconsideredinordertomimicBFmovementevenmoreclosely.
简介:模型的验证是指对模型的性能指标(区分度、校准度)进行考察的过程。根据考察过程中是否使用预测模型的开发队列数据,模型验证可分为内部验证和外部验证。内部验证是检验模型开发过程的可重复性,常见形式包括随机拆分验证、交叉验证、Bootstrap重抽样以及“内部-外部”交叉验证。外部验证考察的是模型的可移植性和可泛化性,常见形式包括时段验证、空间验证以及领域验证。
简介:资本资产定价模型(CAPM)和套利定价理论(APT)是关于资本市场均衡的两个比较著名的模型。二种模型虽然在解释的角度、基本很设、方法、以及适用范围上均有重大区别,但是殊途同归,它们得出的结论是一致的:期望收益与风险之间存在着正相关的关系。