简介:Theconventionalbypassdesignistoimplantagraftonthestenosedhostarteryallowingbloodtoflowbypassthestenoticartery.However,restenosisisachallengingproblemwhichfinallyresultsinreoperation.Thepurposeofthispaperistoproposeanewbypassgraftdesignofcoronaryarterywithanassistantgraftforthetreatmentofcoronaryarterystenosis.AnadditionalassistantgraftwasemployedinthenewdesigncomparedwiththeconventionalETSanastomosis.Numericalsimulationswereperformedbymeansoffinitevolumemethodusingcomputationalfluiddynamics(CFD)solver.ResultsdemonstratedthatthenewanastomosesmodelprovidedamoresmoothflowatthedistalETSanastomosiswithoutanystagnationpointonanastomoticbedandvortexformationintheheelregion.Oscillatoryshearindex(OSI)andtime-averagedwallshearstressgradient(TAWSSG)atthearterybedofthedistalETSanastomosiswerereduced.Thecoronaryarterybypassgraftwithanassistantgraftisfeasibletoimprovethelocalhemodynamicsanddiminishtheprobabilityofrestenosisinthetreatmentofcoronaryarterystenosis.
简介:AbstractProximal tibiofibular instability is a rare condition for which treatment is poorly codified. A 21-year-old patient, a leisure sportswoman, presented a post-traumatic anterolateral instability of the proximal tibiofibular articulation without cartilage lesion. We propose an original surgical technique based on a review of the literature that combines an anatomical ligamentoplasty of the proximal tibiofibular joint and a proximal fibular diaphyseal osteotomy to reduce the distal tibiofibular mechanical stresses. This original technique allows a favorable evolution with recovery of professional and sports activities at 6 months.
简介:Thegraftcopolymerizationofacrylonitrile(AN)ontostarchundertheinitiationofpotassiumperman-ganatewasinvestigated.Theeffectofvariousreactionconditionsonthegraftcopolymerizationwasstudied.Therelationshipsbetweenthegraftingrateandtheinitiatorconcentrationofpotassiumpermanganate,monomeracuylonitrileandbackbonestarch,aswellasreactiontemperaturewereestablished.Theoxidationreactionofstarchwithmanganicionsandvalencechangesofmanganicionsduringthegraftcopolymerizationwerediscussed.TheresultsshowthatmanganicionMn^7+underwentaseriesofvalencechangesduringthegraftcopolymerization:Mn(Ⅶ)→Mn(Ⅳ)→Mn(Ⅲ)→Mn(Ⅱ).Thegraftingrateofthegraftcopolymerizationofacrylonitrileontostarchisalsogiven.
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简介:BACKGROUND:Presently,over40kindsofduralgraftshavebeensuccessivelyusedinclinic.Amongthem,lyophilizedhumanduramaterwithgoodhistocompatibilityandlesscomplicationsisappliedmostwidely.Butthereareafewreportsoncasesofinfectedspongiformencephalopathyfollowingapplicationoflyodura.Moreidealrepairmaterialsdeservetobefurtherinvestigated.OBJECTIVE:Toinvestigatetheefficiencyandsafetyofbiologicalduralgraftmadebymeningesfromporkerstorepairmeningealinjury.DESIGN:Aself-controlobservation.SETTING:WuhanGeneralHospitalofGuangzhouMilitaryAreaCommandofChinesePLA.MATERIALS:SixteenNewZealandRabbits,ofeithergender,weighingfrom2to3kg,ofcleangradeⅡ,withtheageof0.5–1year,wereinvolvedinthisexperiment.TheinvolvedrabbitswereprovidedbytheAnimalExperimentalCenteroftheFirstMilitaryMedicalUniversityofChinesePLA.Biologicalsurgicalpatch(duralgraft)wasdevelopedbyGuangdongGuanhaoBiotechnologicalCo.,Ltd.Itwasprocessedbyusingmeningesfromporkersbytissueengineeringtechnology.METHODS:ThisexperimentwascarriedoutintheExperimentalCenterofthe157HospitalofChinesePLAbetweenDecember2003andJune2004.①Theexperimentalrabbitswereanesthetized.Duramaterwasexposedfromtwosidesofpostmediallineofcoronalsuture.Arectangularduramaterabout8mm×8mminsizewascutoff.Thenabiologicalsurgicalpatch(duralgraft)wasshearedintoinsertwith8mmdiameterandsutured.Theleftduramaterwasuntouchedandusedascontrol.Scalpwassutured,andpostoperativewoundhealingandrecoverywereobserved.②Theanesthetizedrabbitsweresacrificedatpostoperative3,14,30and90days,4rabbitsonce.Thewholeheadwascutoff,anditsscalpwasremoved.Afterwards,theheadwasfixedbyformalin.Tissuesinoperativesitewereobtained,performedroutineparaffinembedding,slicedandconductedHEstaining,finally,thesectionswereobserved.Whitebloodcellsinv
简介:瞄准:与胃肠的graft-versus-host疾病(官方补给的GVHD)在病人评估内视镜检查法的诊断价值。方法:我们与官方补给的GVHD后面的allogeneic识别了8个病人造血的干细胞移植(HSCT)。GVHD组织学地被定义为腺apoptosis的存在,没由另外的煽动性或传染的病原学解释。结果:官方补给的GVHD的症状包括了厌食,恶心,呕吐,水泻,腹的疼痛,官方补给的流血,等等。上面的内视镜的外观从微妙的粘膜浮肿变化了,充血,红斑到明显的侵蚀。Colonoscopic检查显示出弥漫的浮肿,充血,补缀的侵蚀,散布溃疡,腐肉形成并且活跃流血。在官方补给的GVHD的组织学的变化在上皮和薄板propria包括了地窟上皮细胞,地窟的退学学生,和淋巴球的渗入的apoptosis。胃和书籍的右页冒号的参与从diffuse变化了到焦点。结论:内视镜检查法可以在跟随allogeneicHSCT的官方补给的GVHD病人的早诊断起一个重要作用,并且胃肠的活体检视的histologic检查被需要证实最后的诊断。
简介:Photoisomerization(trans-cis)ofazoaromaticcompoundshasbeeninvestigatedextensivelyusingabsorptionspectroscopysince1950s[1].Byirradiationwithlightofwavelengthλ1orλ2,thegeometricconfigurationoftheazobondinazobenzenebasedcompoundscanbereversiblyswitchedfromtranstocis.Thetwostateshavedistinctabsorptionspectra.Thisfeaturewouldallowreversiblestorageofdataonthebasisofcisandtransstateswiththeaidofλ1andλ2.However,thecisstateisthermodynamicallyunstablewithrespecttothetransstate,thereforeathermalrelaxationprocessoccursinthedark(atroomtemperature).Thisthermalback-reactionstronglylimitsthelifetimeofthecisstate,anditisinfluencedbythesubstituentR1andR2,catalysts,temperature,andenvironment(solventpolarity,typeofpolymermatrix)[2].
简介:Objective:Tointroducetheexperienceoftreatingfractureofbothtibiaandfibulawithmicro-invasivepercutaneousplateinternalfixationthroughfracturesiteapproach.Methods:Thedataof15patients(11malesand4females),including14adults(aged22-73years,mean=40years)and1child(aged10years),withfractureofbothtibiaandfibulawerestudiedretrospectivelyinthisstudy.Asmallincisionwasmadeatthefracturesiteoftibia.Thenrepositionwasmadeunderdirectvision,andinternalfixationwasemployedwithsteelplatesinsertingthroughthesmallincision.Results:Anatomicalreductionwasobtained.Nocomplicationwasfound.Unionoccurredontimein14patients.Onecasehealedafterasecondoperation.Conclusions:Micro-invasivepercutaneousplateinternalfixationisbeneficialtothehealingofboneandsofttissues.WithoutX-rayexamination,itisalsoeasytoreachanatomicalreductionandmaketibialinternalfixationwithbothplateswithmicro-invasivepercutaneousplateinternalfixation.
简介:Thestarch/D,L-lactidegraftcopolymersweresynthesizedbyreactingD,L-lactidewithcornstarchinN,N-dimethylacetamide(DMAM)inthepresenceoftriethylamine(NEt3)andanhydrouslithiumchloride.TheeffectofreactiontimeandthemolarratioofD,L-lactidetoglucosestructuralunitofstarchonmonomerconversion(C%),graft(G%)andgraftefficiency(GE%)werestudied,TheC%,G%andGE%couldapproach37.3%179.7%and68.0%,respectivelywhenthemolarratioofD,L-lactidetoglucosestructuralunitofstarchis10:1andthegraftcopolymerizationwascarriedoutat80-85℃for4hrundernitrogenatmosphere.TheFouriertransformsinfra-red(FTIR)spectroscopy.differentialscanningcalorimetry(DSC)andX_raydiffraction(XRD)spectroscopywereusedinordertocharacterizethegraftcopolymers.FTIRspectrashowthatabsorptionbandat1740cm^-1confirmedtheformationofesterbond,indicatingthestarch/D,L-lactidegraftcopolymerswereproduced,theDSCcharacteristicresultsshowthemeltingtemperatureofthegraftcopolymerwereelevatedslightlyasthemolarratioofD,L-lactidetoglucosestructuralunitsofstarchincreasedandtheX-raydiffractionspectrashowthesynthesizedgraftcopolymerswereamorphous.Thedegradabilityofgraftcopolymerwastestedwiththeaidofacid,alkaliandmicrobesuchasbacillussubtilisandstaphylococcusaureus.Theresultsofwaterrsistanceshowthegraftcopolymerproducedcanbeusedasacomponentofimpermeablecoatingforcardboard.