简介：Inanefforttodevelopamethodforcartilagetissueengineering,researcherssuccessfullyusedcartilagecellsfromcowkneejoints.Bycreatingasuccessfulmethodwithconditionsconducivetogrowinghealthycartilagetissue,thefindingscouldhelpleadtoanewtreatmentcureforosteoarthritisusingstemcell-basedtissueengineering.Articularcartilageistissuethatisfoundonallthejointsurfacesinthebody.Sincethetissueis

简介：Background:Thegreatertrochantermarkeriscommonlyusedin3-dimensional(3D)models;however,itsinfluenceonhipandkneekinematicsduringgaitisunclear.Understandingtheinfluenceofthegreatertrochantermarkerisimportantwhenquantifyingfrontalandtransverseplanehipandkneekinematics,parameterswhichareparticularlyrelevanttoinvestigateinindividualswithconditionssuchaspatellofemoralpain,kneeosteoarthritis,anteriorcruciateligament(ACL)injury,andhippain.Theaimofthisstudywastoevaluatetheeffectofincludingthegreatertrochanterintheconstructionofthethighsegmentonhipandkneekinematicsduringgait.Methods:3Dkinematicswerecollectedin19healthysubjectsduringwalkingusingasurfacemarkersystem.Hipandkneeangleswerecomparedacrosstwothighsegmentdefinitions(withandwithoutgreatertrochanter)attwotimepointsduringstance:peakkneeflexion(PKF)andminimumkneeflexion(MinKF).Results:Hipandkneeanglesdifferedinmagnitudeanddirectioninthetransverseplaneatbothtimepoints.Inthethighmodelwiththegreatertrochanterthehipwasmoreexternallyrotatedthaninthethighmodelwithoutthegreatertrochanter(PKF:-9.34°±5.21°vs.1.40°±5.22°,MinKF:-5.68°±4.24°vs.5.01°±4.86°;p<0.001).Inthethighmodelwiththegreatertrochanter,thekneeanglewasmoreinternallyrotatedcomparedtothekneeanglecalculatedusingthethighdefinitionwithoutthegreatertrochanter(PKF:14.67°±6.78°vs.4.33°±4.18°,MinKF:10.54°±6.71°vs.-0.01°±2.69°;p<0.001).Smallbutsignificantdifferencesweredetectedinthesagittalandfrontalplaneanglesatbothtimepoints(p<0.001).Conclusion:Hipandkneekinematicsdifferedacrossdifferentsegmentdefinitionsincludingorexcludingthegreatertrochantermarker,especiallyinthetransverseplane.Thereforewhenconsideringwhethertoincludethegreatertrochanterinthethighsegmentmodelwhenusingasurfacemarkerstocalculate3Dkinematicsformovementassessment,iti

简介：Background:AlthoughTaiJiQuanhasbeenshowntorelievepainandimprovefunctionalmobilityinpeoplewithkneeosteoarthritis(OA),littleisknownaboutitspotentialbenefitsongaitcharacteristicsamongolderChinesewomenwhohaveahighprevalenceofbothradiographicandsymptomatickneeOA.ThisstudyaimstoassesstheefficacyofatailoredTaiJiQuaninterventionongaitkinematicsforolderChinesewomenwithkneeOA.Methods:Arandomizedcontrolledtrialinvolving46olderwomeninShanghai,China,withclinicallydiagnosedkneeOA.Randomized(1:1)participantsreceivedeithera60minTaiJiQuansession(n=23)3timesweeklyora60minbi-weeklyeducationalsession(n=23)for24weeks.Primaryoutcomeswerechangesingaitkinematicmeasuresfrombaselineto24weeks.SecondaryoutcomesincludedchangesinscoresontheWesternOntarioandMcMasterUniversityOsteoarthritisIndex(WOMAC)andShortPhysicalPerformanceBattery(SPPB).Results:After24weekstheTaiJiQuangroupdemonstratedbetterperformanceingaitvelocity(meandifference,8.40cm/s,p=0.01),steplength(meandifference,3.52cm,p=0.004),initialcontactangle(meandifference,2.19°,p=0.01),andmaximalangle(meandifference,2.61°,p=0.003)offlexedkneesduringstancephasecomparedtothecontrolgroup.Inaddition,theTaiJiQuangroupshowedsignificantimprovementinWOMACscores(p<0.01)(meandifference,-4.22pointsinpain,p=0.002;-2.41pointsinstiffness,p<0.001;-11.04pointsinphysicalfunction,p=0.006)andSPPBscores(meandifference,1.22points,p<0.001).Conclusion:AmongolderChinesewomenwithkneeOA,atailoredTaiJiQuaninterventionimprovedgaitoutcomes.TheinterventionalsoimprovedoverallfunctionasindexedbytheWOMACandSPPB.TheseresultssupporttheuseofTaiJiQuanforolderChineseadultswithkneeOAtobothimprovetheirfunctionalmobilityandreducepainsymptomatology.