简介:Inordertoseparatemethylacetateandmethanolazeotrope,theionicliquid(IL)1,3-dimethylimidazoliumdimethylphosphate([DMIM]DMP)wasusedasthesolvent.TheAspenPlussoftwarewasusedtodesignandoptimizetheextractivedistillationprocess.Undertheoptimizedconditions,themassfractionsofmethylacetateandmethanolwerebothabove99.5%.Comparedwiththedimethylsulfoxide(DMSO)process,the[DMIM]DMPprocesshastheadvantagesofsavingenergyandlowerequipmentinvestmentcost.Theresultshowsthatusing[DMIM]DMPasthesolventtoseparateamethylacetateandmethanolazeotropehasbetterprospectinindustrialapplication.
简介:Methyldiethanolaminefattyacidesters,viz.methyldiethanolamineoctanoateandmethyldiethanolamineoleate,wereprepared.Theirimpactsonthebiodegradabilityandtribologicalpropertiesofmineralbaseoil400SNwereevaluatedbyatesterforfastevaluatingthebiodegradabilityoflubricantsandbyafour-balltester,respectively.Theresultsshowedthatmethyldiethanolamineoctanoateandmethyldiethanolamineoleatebothcouldmarkedlypromotethebiodegradationoftheoilandimproveditstribologicalproperties.Theimprovementofbiodegradabilitywasattributedtotheenhancedgrowthandquantityofmicrobesbymethyldiethanolaminefattyacidesters.Thewornsurfaceswereanalyzedbyascanningelectronmicroscope(SEM)equippedwithanenergydispersivespectrometer(EDS)andanX-rayphotoelectronspectroscope(XPS).Theresultsindicatedthattheenhancementoffriction-reducingandanti-wearpropertiesofthemineraloilwasattributedtotheformationofcomplicatedboundarylubricationfilmscomposedofspeciessuchasFe2O3,Fe3O4andorganicnitrogen-containingcompoundswithastructureof–C-N-orR-NH2.
简介:ActiveFe-andMn-loadedMCM-41(Fe–Mn/MCM-41),whichwassynthesizedviaahydrothermalreactionfollowedbyimpregnation,isusedintheheterogeneousFentonreactiontodegrademethylorange(MO)inaqueoussolution.ThesynthesizedsampleswerecharacterizedbyX-raydiffraction,scanningelectronmicroscopy,transmissionelectronmicroscopy,N2adsorption–desorptionisothermanalysis,Fouriertransforminfraredspectroscopy,andX-rayphotoelectronspectroscopy.ComparedwithFe/MCM-41andMn/MCM-41,Fe–Mn/MCM-41showedhigheractivityforMOdegradationandmineralization.Effectsofvariousoperatingparameters,suchaspH,Mncontent,andH2O2dosage,onthedegradationprocessweresubsequentlyinvestigated.ResultsofexperimentsontheeffectofradicalscavengersrevealedthatthedegradationofMOcouldbeattributedtooxidationbyHO·.ThesynergyofFeandMnspeciesintheFentonoxidationprocesswasalsoexplained.
简介:目的探讨DNA修复基因RAD523'非翻译区(3'-untranslatedregion,3'-UTR)miRNA靶序列单核苷酸多态性(singlenucleotidepolymorphism,SNP)与广西地区人群肝细胞癌(hepatocellularcarcinoma,HCC)遗传易感性的关系。方法采用病例-对照研究,对1002例确诊的HCC新发病例和1013例非肿瘤患者RAD52基因3'-UTR区域miRNA靶序列SNPs(rs1051669、rs1051672、rs7301931和rs7310449)进行基因分型,并分析其基因型频率分布及其与HCC遗传易感性的关系。结果RAD52基因各SNP基因型在病例组和对照组中的分布频率差异均无统计学意义(P〉0.05)。调整年龄、性别、吸烟、饮酒和HBV感染等因素后,未发现各SNP与HCC易感性有关联;分层分析发现,在女性人群中,与携带rs1051669C等位基因相比,TT基因型可显著降低个体罹患HCC的风险(TTvsCT/CC:OR=0.03,95%CI:0.00~0.62,P=0.03);与携带rs1051672G等位基因相比,AA基因型可显著降低个体罹患HCC的风险(AAvsGA/GG:OR=0.03,95%CI:0.01~0.88,P=0.04)。结论RAD52基因3'-UTR区域miRNA靶序列SNPsrs1051669、rs1051672位点可能与广西地区女性人群HCC易感性有关。