简介:ASchwanncellhasregenerativecapabilitiesandisanimportantcellintheperipheralnervoussystem.ThismicroarraystudyispartofabioinformaticsstudythatfocusesmainlyonSchwanncells.Microarraydataprovideinformationondifferencesbetweenmicroarray-basedandexperiment-basedgeneexpressionanalyses.Accordingtomicroarraydata,severalgenesexhibitincreasedexpression(foldchange)buttheyareweaklyexpressedinexperimentalstudies(basedonmorphology,proteinandmRNAlevels).Incontrast,somegenesareweaklyexpressedinmicroarraydataandhighlyexpressedinexperimentalstudies;suchgenesmayrepresentfuturetargetgenesinSchwanncellstudies.Thesestudiesallowustolearnaboutadditionalgenesthatcouldbeusedtoachievetargetedresultsfromexperimentalstudies.Inthecurrentbigdatastudybyretrievingmorethan5000scientificarticlesfromPubMedorNCBI,GoogleScholar,andGoogle,1016(up-anddownregulated)genesweredeterminedtoberelatedtoSchwanncells.However,noexperimentwasperformedinthelaboratory;rather,thepresentstudyispartofabigdataanalysis.OurstudywillcontributetoourunderstandingofSchwanncellbiologybyaidingintheidentificationofgenes.Basedonacomparativeanalysisofallmicroarraydata,weconcludethatthemicroarraycouldbeagoodtoolforpredictingtheexpressionandintensityofdifferentgenesofinterestinactualexperiments.
简介:过去三十年间,考试影响已经被认为是考试效度验证中后果方面的重要证据,在语言测评领域引起了越来越多的关注。此方面现有研究多关注于测试对课堂内教学的影响(通常称之为“反拨效应”),而对测试在课堂之外的个体、政策及实践等社会层面的影响研究甚少。为此,本文研究了2011年至2017年间两种国家级报纸的数据,以此分析高考对于中国教育社会层面的影响。文献分析的结果显示了高考在诸多方面的巨大影响,包括考试内容、施考、利益相关方承受的压力、学校教学实践、教育政策等方面,特别是举国瞩目的现行高考改革。我们的分析显示考试内容设计需更多关注农村考生群体,考试需系统地提供更具包容性的施考程序,以及高考改革的成功需有课程及教法的配套改革支持。
简介:Utilizingdatafromcontrolledseismicsourcestoimagethesubsurfacestructuresandinvertthephysicalpropertiesofthesubsurfacemediaisamajoreffortinexplorationgeophysics.Denseseismicrecordswithhighsignal-to-noiseratio(SNR)andhighfidelityhelpsinproducinghighqualityimagingresults.Therefore,seismicdatadenoisingandmissingtracesreconstructionaresignificantforseismicdataprocessing.Traditionaldenoisingandinterpolationmethodsrarelyoccasionedrelyonnoiselevelestimations,thusrequiringheavymanualworktodealwithrecordsandtheselectionofoptimalparameters.Weproposeasimultaneousdenoisingandinterpolationmethodbasedondeeplearning.Fornoisyrecordswithmissingtraces,weadoptaniterativealternatingoptimizationstrategyandseparatetheobjectivefunctionofthedatarestoringproblemintotwosub-problems.Theseismicrecordscanbereconstructedbysolvingaleast-squareproblemandapplyingasetofpre-traineddenoisingmodelsalternativelyanditeratively.Wedemonstratethismethodwithsyntheticandfielddata.
简介:Duetodramaticallyincreasinginformationpublishedinsocialnetworks,privacyissueshavegivenrisetopublicconcerns.Althoughthepresenceofdifferentialprivacyprovidesprivacyprotectionwiththeoreticalfoundations,thetrade-offbetweenprivacyanddatautilitystilldemandsfurtherimprovement.However,mostexistingstudiesdonotconsiderthequantitativeimpactoftheadversarywhenmeasuringdatautility.Inthispaper,wefirstlyproposeapersonalizeddifferentialprivacymethodbasedonsocialdistance.Then,weanalyzethemaximumdatautilitywhenusersandadversariesareblindtothestrategysetsofeachother.Weformalizeallthepayofffunctionsinthedifferentialprivacysense,whichisfollowedbytheestablishmentofastaticBayesiangame.Thetrade-offiscalculatedbyderivingtheBayesianNashequilibriumwithamodifiedreinforcementlearningalgorithm.Theproposedmethodachievesfastconvergencebyreducingthecardinalityfromnto2.Inaddition,thein-placetrade-offcanmaximizetheuser'sdatautilityiftheactionsetsoftheuserandtheadversaryarepublicwhilethestrategysetsareunrevealed.Ourextensiveexperimentsonthereal-worlddatasetprovetheproposedmodeliseffectiveandfeasible.
简介:模型的验证是指对模型的性能指标(区分度、校准度)进行考察的过程。根据考察过程中是否使用预测模型的开发队列数据,模型验证可分为内部验证和外部验证。内部验证是检验模型开发过程的可重复性,常见形式包括随机拆分验证、交叉验证、Bootstrap重抽样以及“内部-外部”交叉验证。外部验证考察的是模型的可移植性和可泛化性,常见形式包括时段验证、空间验证以及领域验证。
简介:Vertical-cavitysurface-emittinglasers(VCSELs)aretheidealopticalsourcesfordatacommunicationandsensing.Indatacommunication,largedataratescombinedwithexcellentenergyefficiencyandtemperaturestabilityhavebeenachievedbasedonadvanceddevicedesignandmodulationformats.VCSELsarealsopromisingsourcesforphotonicintegratedcircuitsduetotheirsmallfootprintandlowpowerconsumption.Also,VCSELsarecommonlyusedforawidevarietyofapplicationsintheconsumerelectronicsmarket.Theseapplicationsrangefromlasermicetothree-dimensional(3D)sensingandimaging,includingvarious3Dmovementdetections,suchasgesturerecognitionorfacerecognition.NovelVCSELtypeswillincludemetastructures,exhibitingadditionaluniqueproperties,oflargestimportancefornext-generationdatacommunication,sensing,andphotonicintegratedcircuits.
简介:Asusersincreasinglybefriendothersandinteractonlineviatheirsocialmediaaccounts,onlinesocialnetworks(OSNs)areexpandingrapidly.Confrontedwiththebigdatageneratedbyusers,itisimperativethatdatastoragebedistributed,scalable,andcost-efficient.Yetoneofthemostsignificantchallengesaboutthistopicisdetermininghowtominimizethecostwithoutdeterioratingsystemperformance.Althoughmanystoragesystemsusethedistributedkeyvaluestore,itcannotbedirectlyappliedtoOSNstoragesystems.Andbecauseusers'dataarehighlycorrelated,hashstorageleadstofrequentinter-servercommunications,andthehighinter-servertrafficcostsdecreasetheOSNstoragesystem'sscalability.Previousstudiesproposedconductingnetworkpartitioninganddatareplicationbasedonsocialgraphs.However,datareplicationincreasesstoragecostsandimpactstrafficcosts.Here,weconsiderhowtominimizecostsfromtheperspectiveofdatastorage,bycombiningpartitioningandreplication.Ourcost-efficientdatastorageapproachsupportsscalableOSNstoragesystems.Theproposedapproachco-locatesfrequentlyinteractiveuserstogetherbyconductingpartitioningandreplicationsimultaneouslywhilemeetingload-balancingconstraints.Extensiveexperimentsareundertakenontworeal-worldtraces,andtheresultsshowthatourapproachachieveslowercostcomparedwithstate-of-the-artapproaches.ThusweconcludethatourapproachenableseconomicandscalableOSNdatastorage.
简介:Asanefficienttoolinhandlinguncertainissues,Dempster-Shaferevidencetheoryhasbeenincreasinglyusedinstructuralhealthmonitoringanddamagedetection.Inapplications,however,Dempster-Shaferevidencetheorysometimesleadstocounter-intuitiveresults.Inthisstudy,anewfusionalgorithmofevidencetheoryisputforwardtoaddressvariouscounter-intuitiveproblemsandmanagethereliabilitydifferenceoftheevidence.Theproposedalgorithmcomprisesthefollowingaspects:(1)Dempster’scombinationruleisgeneralizedbyintroducingtheconceptofevidenceullage.ThenewruleallowsclassicalDempster’sruleandcanresolvecounter-intuitiveproblemscausebyevidenceconflictandevidencecompatibility;(2)areliabilityassessingmethodbasedonaprioriandposteriorknowledgeisproposed.Comparedwithconventionalreliabilityassessment,theproposedmethodcanreflecttheactualevidencereliabilitiesandcanefficientlyreducedecisionrisk.Numericalexamplesconfirmthevalidityandutilityoftheproposedalgorithm.Inaddition,anexperimentalinvestigationonaspatialtrussstructureiscarriedouttoillustratetheidentifiedabilityoftheproposedapproach.Theresultsindicatethatthefusionalgorithmhasnostrictrequestontheaccuracyandconsistencyofevidencesourcesandcanefficientlyenhancediagnosticaccuracy.
简介:Usingfoursatellitedatasets(TOMS/SBUV,OMI,MLS,andHALOE),weanalyzetheseasonalvariationsofthetotalcolumnozone(TCO)anditszonaldeviation(TCO*),andrevealtheverticalstructureoftheOzoneLow(OV)overtheAsiancontinent.Ourprincipalfindingsare:(1)TheTCOovertheAsiancontinentreachesitsmaximuminthespringanditsminimumintheautumn.TheOzoneLowexistsfromMaytoSeptember.(2)TheOzoneLowhastwonegativecores,locatedinthelowerandtheupperstratosphere.Thelowercoreisnear30hPainthewinterand70hPaintheotherseasons.Theuppercorevariesfrom10hPato1hPaamongthefourseasons.(3)ThepositionoftheOzoneLowinthelowerandtheupperstratosphereovertheAsiancontinentshowsseasonalvariability.
简介:TheGarouaZoneinNorthCameroon,thesubjectofthisstudy,isknowntohaveundergonetectonicmovementsduringtheCretaceous,butthezone’sstructuraldataremainpoorlyknown.ThisstudyexploitstheBougueranomalytoimproveknowledgeofGarouatectonicsstructures.Inordertocharacterizethesestructures,twomethodsareused:Euler’sdeconvolutionmethodandthemethodofthehorizontalgradientoftheverticalderivative.SuperpositionoftheEuler’ssolutionsmapforindexN=1withthemapfromthehorizontalgradientoftheverticalderivativemethodallowsdeterminationofgravimetriclineaments,interpretedasfaultsoraslinearcontacts,fromwhichwededuceastructuralmapofthestudyarea.Basedonthismap,weidentifysixteenlineaments,ofwhichwecounteightaslinearcontactsandeightasfaults.Amongthefaults,wedenoteoneofdepthbetween4and8km,fivefaultsofdepthrangingbetween8and13km,andtwofaultsofdepthsbetween13and36km.Analysisofthesefaultsshowsthatthesevendeepestfaultsmightpresentanaturalriskinourstudyarea.Forpurposesofcivilprotection,suchdeepfaultsshouldbemonitoredandtakenintoconsiderationintheimplementationoflargepublicworks.Thestructuralmap,establishedhereinfromdataonthein-depthextensionofeachfault,thusincreasesscientificknowledgeintheareathatcanbeusedtositepublicworksinwaysthatreducerisk.
简介:Withthegrowingpopularityofcloud-baseddatacenternetworks(DCNs),taskresourceallocationhasbecomemoreandmoreimportanttotheefficientuseofresourceinDCNs.Thispaperconsidersprovisioningthemaximumadmissibleload(MAL)ofvirtualmachines(VMs)inphysicalmachines(PMs)withunderlyingtree-structuredDCNsusingthehosemodelforcommunication.Thelimitationofstaticloaddistributionisthatitassignstaskstonodesinaonce-and-for-allmanner,andthusrequiresaprioriknowledgeofprogrambehavior.Toavoidloadredistributionduringruntimewhentheloadgrows,weintroducemaximumelasticityscheduling,whichhasthemaximumgrowthpotentialsubjecttothenodeandlinkcapacities.Thispaperaimstofindtheschedulewiththemaximumelasticityacrossnodesandlinks.Wefirstproposeadistributedlinearsolutionbasedonmessagepassing,andwediscussseveralpropertiesandextensionsofthemodel.Basedontheassumptionsandconclusions,weextendittothemultiplepathscasewithafattreeDCN,anddiscusstheoptimalsolutionforcomputingtheMALwithbothcomputationandcommunicationconstraints.Afterthat,wepresenttheprovisionschemewiththemaximumelasticityfortheVMs,whichcomeswithprovableoptimalityguaranteeforafixedflowschedulingstrategyinafattreeDCN.Weconducttheevaluationsonourtestbedandpresentvarioussimulationresultsbycomparingtheproposedmaximumelasticschedulingschemeswithothermethods.Extensivesimulationsvalidatetheeffectivenessoftheproposedpolicies,andtheresultsareshownfromdifferentperspectivestoprovidesolutionsbasedonourresearch.
简介:Cloudcomputingisatechnologythatprovidesuserswithalargestoragespaceandanenormouscomputingpower.However,theoutsourceddataareoftensensitiveandconfidential,andhencemustbeencryptedbeforebeingoutsourced.Consequently,classicalsearchapproacheshavebecomeobsoleteandnewapproachesthatarecompatiblewithencrypteddatahavebecomeanecessity.Forprivacyreasons,mostoftheseapproachesarebasedonthevectormodelwhichisatimeconsumingprocesssincetheentireindexmustbeloadedandexploitedduringthesearchprocessgiventhatthequeryvectormustbecomparedwitheachdocumentvector.Tosolvethisproblem,weproposeanewmethodforconstructingasecureinvertedindexusingtwokeytechniques,homomorphicencryptionandthedummydocumentstechnique.However,1)homomorphicencryptiongeneratesverylargeciphertextswhicharethousandsoftimeslargerthantheircorrespondingplaintexts,and2)thedummydocumentstechniquethatenhancestheindexsecurityproduceslotsoffalsepositivesinthesearchresults.Theproposedapproachexploitstheadvantagesofthesetwotechniquesbyproposingtwomethodscalledthecompressedtableofencryptedscoresandthedoublescoreformula.Moreover,weexploitasecondsecureinvertedindexinordertomanagetheusers'accessrightstothedata.Finally,inordertovalidateourapproach,weperformedanexperimentalstudyusingadatacollectionofonemilliondocuments.Theexperimentsshowthatourapproachismanytimesfasterthananyotherapproachbasedonthevectormodel.
简介:Weanalyzed360permanentandcampaignGPSdatafrom1999to2017inthesouthernSichuan-Yunanblock,andobtainedcrustalhorizontaldeformationinthisregion.Then,wederivedthestrainrateusingamulti-scalesphericalwaveletmethod.ResultsrevealacomplexpatternoftectonicmovementinthesouthernSichuan-Yunnanblock.ComparedtothestableEurasianplate,themaximumrateofthehorizontaldeformationinthesouthernSichuan-Yunnanblockisapproximately22mm/a.TheXiaojiangfaultshowsasignificantlylowerdeformation—aleft-lateralstrike-slipmovementof9.5mm/a.TheHonghefaultclearlyshowsacomplexsegmentaldeformationfromthenorthtosouth.ThenorthernHonghefaultshows4.3mm/arightstrike-slipwith6.7mm/aextension;thesouthernHonghefaultshows1.9mm/arightstrike-slipwith1.9mm/aextension;thejunctionzoneintheHongheandLijiang–Xiaojinhefaultsshowsanobviousclockwise-rotationdeformation.Thestraincalculationresultsrevealthatthemaximumshear-strainrateinthisregionreaches70nstrain/a,concentratedaroundtheXiaojiangfaultandatthejunctionoftheHongheandLijiang–Xiaojinhefaults.Wenotethatmostoftheearthquakeswithmagnitudesof4andabovethatoccurredinthisregionwerewithinthehighshearstrain-ratezonesandthestrainrategradientboundaryzone,whichindicatesthatthemagnitudeofstrainaccumulationiscloselyrelatedtotheseismicactivities.Comparisonofthefastshear-wavepolarizationdirectionoftheupper-crustwiththeupper-mantleanisotropyandthedirectionofthesurfaceprincipalcompressivestrainrateobtainedfromtheinversionoftheGPSdatarevealsthatthedirectionofthesurfaceprincipalcompressivestrainisbasicallyconsistentwiththefastshear-wavepolarizationdirectionoftheuppercrustanisotropy,butdifferentfromthepolarizationdirectionoftheuppermantle.OurresultssupportthehypothesisthattheprincipalelementsofthedeformationmechanisminthesouthernSichuan-Yunnanblockaredeco
简介:Environmentalloadistheprimaryfactorinthedesignofoffshoreengineeringstructuresandoceancurrentistheprincipalenvironmentalloadthatcausesunderwaterstructuralfailure.Incomputationalanalysis,thecalculationofcurrentloadismainlybasedonthecurrentprofile.Thecurrentprofilemodel,whichisbasedonastructuralfailurecriterion,isconducivetodecreasingtheuncertaintyofthecurrentload.Inthisstudy,weusedprototypemonitoringdataandtheempiricalorthogonalfunction(EOF)methodtoinvestigatethecurrentprofileintheSouthChinaSeaanditscorrelationwiththedesignofunderwaterstructuralstrengthandthedynamicdesignoffatigue.Theunderwaterstructuralstrengthdesigntakesintoaccountthesizeofthestructureandtheservicewaterdepth.Weproposeprofilesfortheoverallandlocaldesignsusingtheinversefirst-orderreliabilitymethod(IFORM).Weextractedthecharacteristicprofilecurrent(CPC)ofthemonitoredseaareatosolvedynamicdesignproblemssuchasvortex-inducedvibration(VIV).WeusedrandomsamplingtoverifythefeasibilityofusingtheEOFmethodtocalculatetheCPCfromthecurrentdataandidentifiedthemainproblemsassociatedwithusingtheCPC,whichdeservecloseattentioninVIVdesign.Ourresearchconclusionsprovidedirectreferencesfordeterminingcurrentloadinthisseaarea.Thisanalysismethodcanalsobeusedintheanalysisofotherseaareasorfieldvariables.
简介:Thebrownstinkbug(BSB),Euschistusservus(Say)(Hemiptera:Pentatomidae),isaseriouseconomicpestofcornproductioninthesoutheasternUnitedStates.TheBSBpopulationdynamicswasmonitoredfor17weeksfromtasselingtopreharvestofcornplants(i.e.,lateMaytomid-September)usingpheromonetrapsinthreecornfieldsfrom2005to2009.ThetrapdatashowedtwopeaksinearlyJuneandmid-August,respectively.Therelationshipbetweentrapcatchandpregrowingseasonweatherdatawasexaminedusingcorrelationandstepwisemultiplefactorregressionanalyses.Weatherindicesusedfortheanalyseswereaccumulatedgrowingdegreeday(AGDD),numberofdayswithminimumtemperaturebelow0℃(Subz),accumulateddailymaximum(AMaxT)andminimumtemperatures(AMinT)andrainfall(ARain).Theweatherindiceswerecalculatedwithlower(10℃)andupper(35℃)asbiologicalthresholds.Theparametersusedinregressionanalysiswereseasonalabundance(oroverallmeanofBSBadultcatch)(BSBm),numberofBSBadultscaughtatapeak(PeakBSB),andpeakweek(Peakwk).TheBSBmwasnegativelyrelatedtohightemperature(AmaxTorAGDD)consistently,whereasIstPeakBSBwaspositivelycorrelatedtobothARainandSubz,irrespectiveofweatherdatadurations(thefirst4,4.5,and5months).Incontrast,the7-monthweatherdata(AGDD7)werenegativelycorrelatedtotheBSBmonly,butnotcorrelatedtothesecondPeakBSB.The5-yearmonitoringstudydemonstratedthatweatherdatacanbeusedtopredicttheBSBabundanceatitsfirstpeakintasselingcornfieldsinthesoutheasternU.S.states.
简介:摘要吸烟有很高的风险,它会提高各种疾病得病率。现已证实常年吸烟的人100%会得慢性阻塞性肺病。吸烟导致人口死亡率在未来几年内保持显著水平。吸烟致死率在不同国家大致相似。