简介:Afirstgradeteachercollectedwell-knownproverbs.Hegaveeachkidintheclassthefirsthalfoftheproverb,andaskedthemtocomeupwiththerest.Hereiswhatthekidscameupwith:
简介:Inthepresentpaper,theauthorgivessomecommentsonacupuncturetreatmentofdiseasesfrom1)selectingacupointsbasedonseasonalconditions;2)performingreinforcingorreducingneedlingmanipulationsinaccordancewiththewaxingandwanningofthemoon;3)conductingacupuncturetreatmentinaccordancewiththetimeandthestateofdisease;and4)performingacupuncturetreatmentbasedontheprosperityordeclineofthemeridian-qi,whicharedescribedinmedicalbookTheYellowEmperor'sInternalClassic.
简介:Thechangeoftheconfinedaquiferlevelreflectstheporepressurechange,andtheporepressurechangeoftheaquiferiscloselyrelatedtotheaquiferpressure.ThispaperusesthetidalresponseofthewellwaterleveldataintheNorthChinaregiontocalculatethetidalfactorofeachwellandextracttheeffectivewatertrendinformation.Then,thevolumetricstrainofanexistingconfinedaquiferwellintheNorthChinaregionisinverted,andthecontourmapsareplottedonahalf-yearscalefrom2009to2012.ResultsshowthatitcanreflectthestateofstressandstrainindeepcrusttoacertainextentintheNorthChinaregion.
简介:Objective:Ki-67playsanimportantfunctionincelldivision,butitsexactroleisstillunknown.Moreover,fewworksregardingitsoverallfunctionwerepublished.ThepresentstudyevaluatedtheclinicalsignificanceofKi-67indexasaprognosticmarkerandpredictorofrecurrenceindifferentmolecularsubtypesofbreastcancer.TherelationshipofKi-67indexwithdifferentclinicopathologicalfactorswasalsoanalyzed.Methods:Ki-67indexwasmeasuredin107casesofprimarybreastcancerfrom2010-2012.Thesepatientswereevaluatedforestrogenreceptor,progesteronereceptor,andHER2.Ki-67wasdividedaccordingtopercentagelevels:<15%and>15%.Followuprangedfrom32monthsupto6years.Results:Approximately44,23,15,and25casesweregroupedasluminalA,luminalB,HER2subtype,andtriple-negative(TN),respectively.NoluminalApatientsshowedKi-67levelhigherthan15%,andtheirrecurrencewas20%.InluminalBgroup,Ki-67levelhigherthan15%wasobservedin69%ofpatients,andrecurrencewas39%.InHER2subtype,Ki-67washigherthan15%in34%ofcases,andrecurrencewas40%.Intriple-negativecases,Ki-67washigherthan15%in60%ofcases,andrecurrencewasdetectedin32%ofpatients.PatientswithKi-67lessthan15%displayedbetteroverallsurvivalthanthosewithKi-67higherthan15%(P=0.01).PatientswithKi-67higherthan15%exhibitedhigherincidenceofmetastasisandrecurrencethanthosewithKi-67lessthan15%(P=0.000).Conclusions:Ki-67maybeconsideredasavaluablebiomarkerinbreastcancerpatients.
简介:Inthepresentpaper,theauthorintroduceshisindividualexperienceandunderstandingsaboutacupuncturetreatmentoflumbagofrom①pathogeniccausesandpathogenesis,②syndromedifferentiationandanalysis,③therapeuticmethods,④treatmentaccordingtodifferentiationofsyndromes,and⑤keypointsabouttreatmentoflumbago.Theauthorstressesthatinthetreatmentoflumbago,neverforgetreinforcingthekidneyandtreatboththeprimaryandsecondaryaspectsofthediseaseatthesametime.
简介:Inordertodeterminetheappropriatetreatmentinterval,267patientswhounderwent3sessionsoftreatmentwithQ-switchedalexandritelaserweredividedinto4groupsaccordingtotreatmentinterval,andtheirclinicalresponseswerecompared.Amongthem,187wereaskedabouttheprocessofpigmentfading.Moreover,lightandtransmissionelectronmicroscopywereperformed.Itwasnotedthattheclinicalresponseofthe5-6monthintervalgroupwassignificantlybetterthanthatofthe3-4monthgroup,butshowednosignificantdifferencefromthatofthe7-8or≥9monthgroup.80.21%ofinvestigatedpatientsstatedthatmarkedpigmentfadingcouldnolongerbeobserved7monthsafterirradiation.4monthsafterirradiation,thedegeneratedmelanosomesandcelldebriswerestillscatteredamongcollagenfibers,scavengedgraduallybymacrophage.Inconclusion,anappropriatetreatmentintervalis5-6months.
简介:因为背带沿着结构的外面的脸被安装,结构没有列,一般常规塑造的diagrid结构能表示多样的形状。自从不规则的塑造的结构有多样的变量,估计源于各种各样的变量的行为的研究不管多么是连续地要求了补充与如此的变量有关的瑕疵。在现在的学习,材料橡皮模量和收益力量为将被用于在在不规则的塑造的大楼之中的龙卷风形式的结构的系统由Vollers分类的diagrid并且影响这些结构的系统的结构的设计的力量作为变量被选择。这研究的目的根据在钩住角度的变化是结构的系统到为轴的旋转diagrid的行为敏感分析以便识别在钩住角度和轴的旋转角度根据变化有相对更大的效果和结构的敏感的趋势的设计变量。
简介:Thisstudyrepresentstheinfluenceonexhaustperformancebyactivemufflervalvespring.Themainexperimentalparameterswereenginespeedsandtorsioncoilspringconstantsintheactivemuffler.Whenthemufflervalvespringhasalowspringconstantofk=0.75,thesoundpressurelevelwaslowattheregionofenginespeed2000to2500r/min,andthevelocityofexhaustgaswashighatspringconstantk=0.75.Whentheenginespeedwasunder1500r/min,themeanconcentrationofCOwashighincasewithoutmufflervalve.Whentheenginespeedintherangeof1600to2600r/minwithspringconstantk=0.75,themeanHCconcentrationshowedthelowestvalue.Withoutmufflervalve,thetemperatureinthemufflerwashigherthanthecasewithmufflervalve.Thisresearchrepresentedthattheperformanceoftheactivemufflervalvespringconstantk=0.75washigherthanthatwithoutmufflervalveandvalvespringconstantk=0.70.Amongthethreecasesofexperimentalcondition,withaspringcon
简介:Naturalproducts(NPs)arecompoundsthatarederivedfromnaturalsourcessuchasplants,animals,andmicroisms.Therapeuticshasbenefitedfromnumerousdrugclassesderivedfromnaturalproductsources.TheBiopharmaceuticsDrugpositionClassificationSystem(BDDCS)wasproposedtoserveasabasisforpredictingtheimportanceoftransportersandenzymesindeterminingdrugbioavailabilityanddisposition.Itcategorizesdrugsintooneoffourbiopharmaceuticalclassesaccordingtotheirwatersolubilityandextentofmetabolism.Thepresentpaperreviews109drugsfromnaturalproductsources:29%belongtoclass1(highsolubility,extensivemetabolism),22%toclass2(lowsolubility,extensivemetabolism),40%toclass3(highsolubility,poormetabolism),and9%toclass4(lowsolubility,poormetabolism).HereinweevaluatedthecharacteristicsofNPsintermsofBDDCSclassforall109drugsaswellsasforsubsetsofNPsdrugsderivedfromplantsourcesasantibiotics.Inthe109NPsdrugs,wepiled32drugsfromplants,50%(16)oftotalinclass1,22%(7)inclass2and28%(9)inclass3,nonefoundinclass4;Meantime,theantibioticswerefound5(16%)inclass2,22(71%)inclass3,and4(13%)inclass4;nodrugwasfoundinclass1.Basedonthisclassification,weanticipateBDDCStoserveasausefuladjunctinevaluatingthepotentialcharacteristicsofnewnaturalproducts.
简介:AbstractPurpose:Patients’ gender, which can be one of the most important determinants of traumatic brain injury (TBI) outcomes, is also likely to interact with many other outcome variables of TBI. This multicenter descriptive study investigated gender differences in epidemiological, clinical, treatment, mortality, and variable characteristics in adult TBI patients.Methods:The selection criteria were defined as patients who had been diagnosed with TBI and were admitted to the hospital between January 1, 2016 and December 31, 2018. A total of 4468 adult TBI patients were enrolled at eight University Hospitals. Based on the list of enrolled patients, the medical records of the patients were reviewed and they were registered online at each hospital. The registered patients were classified into three groups according to the Glasgow coma scale (GCS) score: mild (13 -15), moderate (9-12), and severe (3-8), and the differences between men and women in each group were investigated. The risk factors of moderated and severe TBI compared to mild TBI were also investigated.Results:The study included 3075 men and 1393 women and the proportion of total males was 68.8%. Among all the TBI patients, there were significant differences between men and women in age, past history, and GCS score. While the mild and severe TBI groups showed significant differences in age, past history, and clinical symptoms, the moderate TBI group showed significant differences in age, past history, cause of justice, and diagnosis.Conclusion:To the best of our knowledge, this multicenter study is the first to focus on gender differences of adult patients with TBI in Korea. This study shows significant differences between men and women in many aspects of adult TBI. Therefore, gender differences should be strongly considered in TBI studies.
简介:我们在经历了激进的前列腺切除术(RP)的病人之中根据前列腺癌症的clinicopathological特征调查了瘤参与(PTI)的百分比的预示的意义。没有任何neoadjuvant或辅助治疗,经历了在2003年9月和2008年3月之间的RP的534个病人的回顾的研究被执行。有各种各样的clinicopathological特征和生物化学的没有复发的幸存的PTI的协会经由uni-和multivariate分析被检验。multivariate模型的预兆的精确性与在曲线下面操作导出特征的区域的接收装置被估计。PTI被表明显著地与外科手术前的前列腺特定的抗原(PSA)被联系水平(P=0.001),病理学的格利森分数(P<;0.001),extraprostatic瘤扩展(P<;0.001),精囊侵略(P<;0.001)并且积极外科的边缘(P<;0.001)在univariate分析。当病人们被成层进疾病风险组时,PTI在低风险的组(P=0.033)然而并非中介之中仅仅是在multivariate分析的生物化学的没有复发的幸存的一个独立预言者--(P=0.287)或高风险的组(P=0.828)。PTI的增加显著地没增加分别地在彻底的病人(P=0.459)和低风险的组(P=0.268)之中为生物化学的没有复发的幸存的预言设计的multivariate模型的精确性。在结论,尽管PTI看起来比在有更高的风险疾病的那些之中是在有低风险的疾病的病人之中的一个更重要的预示的因素,总的来说,PTI不能提供在罐头已经经由确定的预示的因素被获得的以外的另外的预示的信息。
简介:AIMTo根据国际标准组织(ISO)把IOPen和ICare反弹tonometry比作Goldmannapplanationtonometry(GAT)8612criteria.METHODSTotally,191只眼睛(n=107个人)被包括。ISO8612的标准被完成:IOP的3簇,由GAT测量了,被形成。GAT结果作为吝啬的瑡敩瑮?湵敤杲楯杮挠瑡牡捡?桰捡敯畭獬晩捩瑡潩?敷敲爠湡潤業敺?湩潴琠潷朠潲灵被给吗?