简介:Withinthenervoussystem,regenerationislimited,andthisisduetothesmallamountofneuralstemcells,theinhibitoryoriginofthestemcellnicheandoftentothedevelopmentofascarwhichconstitutesamechanicalbarrierfortheregeneration.Regardingtheseaspects,manyeffortshavebeendoneintheresearchofacellcomponentthatcombinedwithscaffoldsandgrowthfactorscouldbesuitablefornervousregenerationinregenerativemedicineapproaches.Autologousmesenchymalstemcellsrepresentnowadaystheidealcandidateforthisaim,thanktotheirmultipotencyandtotheiramountinsideadulttissues.However,issuesintheirharvesting,throughtheuseofinvasivetechniques,andproblemsinvolvedintheirageing,requiretheresearchofnewautologoussources.Tothispurpose,therecentdiscoveryofastemcellscomponentinteeth,andwhichderivefromneuralcrestcells,hascametothelightthepossibilityofusingdentalstemcellsinnervoussystemregeneration.Inthiswork,inordertogiveguidelinesontheuseofdentalstemcellsforneuralregeneration,webrieflyintroducetheconceptsofregenerationandregenerativemedicine,wethenfocustheattentiononodontogenesis,whichinvolvestheformationandthepresenceofastemcomponentindifferentpartsofteeth,andfinallywedescribesomeexperimentalapproacheswhichareexploitingdentalstemcellsforneuralstudies.
简介:RuralPopulationMovementinChinaWeiJinshengThreecategoriesofruralpopulationmovementinChina(1)Migrationofruralresidentstourbanar...
简介:与在关于的研究的进步一起前寒武纪,Molar-toothcarbonates(作为MT,或microsparite碳酸盐或MT结构简化了)它被形成在theMiddle迟了最近原生地成为了一个风骚的题目。原生地臼齿牙齿(MT)碳酸盐岩石指那些中央--到Neoproterozoic(1600-650妈),有MT的碳酸盐组织,即,一系列古怪,ptygmatically合拢了并且在前寒武纪的年龄的有细密纹理的碳酸盐的充满圆材的裂缝,在环境定位了中间--到内部斜面和浅站台。山象与器官的连接无机的世界的一座桥一样,是仔细与paleo海洋,空气和生物圈的进化有关。他们与生命起原和海洋的碳酸盐的沉积地球化学事件的分离有关的发展或衰退are/is。由足够地使用现代仪器和严峻的方法,在沙岩的氧化物的内容我们remeasured和REE分发模式曲线被建立;~(87)的同位素的比率的精确价值Sr/~(86)Sr被获得,也就是说MT形成的年龄在附近750-900妈;一些新鲜micrite石灰石样品的C和Oisotopes被分析;,精力光谱分析至于它的化学成分表明MT主要由micros同等方解石组成,矩阵显示出Ca,Mg,艾尔,Si,和K的突出的山峰。geochemical证明在吉林辽宁区域的thatNeoproterozoicMT碳酸盐在一个稳定的大陆的边缘被开发,在paleo温度是大约50℃的炽热的地区,当MT在东方辽宁在南部的吉林并且在YingchengziandXingmincun时期期间在Wanlong时期期间被形成时,海水有正常咸度。沉积环境位于内部斜面。在摘要,理解MT的起源是很重要的,查明thepaleo气候和paleo环境特征,抑制年龄和stratigraphicdivision和比较原生地以便学习MTcarbonates和他们的形成环境的geochemical特征。
简介:Mammaliantoothdevelopmentislargelydependentonsequentialandreciprocalepithelial-mesenchymalinteractions.Theseprocessesinvolveaseriesofinductiveandpermissiveinteractionsthatresultinthedetermination,differentiation,andorganizationofodontogenictissues.Multiplesignalingmolecules,includingBMPs,FGFs,Shh,andWntproteins,havebeenimplicatedinmediatingthesetissueinteractions.Transcriptionfactorsparticipateinepithelial-mesenchymalinteractionsvialinkingthesignalingloopsbetweentissuelayersbyrespondingtoinductivesignalsandregulatingtheexpressionofothersignalingmolecules.Adultstemcellsarehighlyplasticandmultipotent.Thesecellsincludingdentalpulpstemcellsandbonemarrowstromalcellscouldbereprogrammedintoodontogenicfateandparticipatedintoothformation.Recentprogressinthestudiesofmolecularbasisoftoothdevelopment,adultstemcellbiology,andregenerationwillprovidefundamentalknowledgefortherealizationofhumantoothregenerationinthenearfuture.
简介:综述了Molar-Tooth的时空分布及其形态特征.Molar-Tooth为元古代时期全球性的一种构造现象.其成因,地质学家们已争论了一个多世纪,直到今天还未取得一致的认担.归纳前人的研究成果,初步坠为Molar-Tooth的成因与藻类等生物活动有关.
简介:Distinguishingwithtraditionaltoothprofileofspiralbevelandhypoidgear,itproposedanewtoothprofilenamelythesphericalinvolute.Firstly,anewtheoryofformingthesphericalinvolutetoothprofilewasproposed.Then,thistheorywasappliedtocompleteparametricderivationofeachpartofitstoothprofile.Forenhancingtheprecision,theSWEEPmethodusedforformationofeachpartoftoothsurfaceandG1stitchingschemaforobtainingaunifiedtoothsurfaceareputforwardandmadetheapplicationintheaccuratemodeling.Lastly,owingtothehigheraccuracyoftoothsurfaceofoutputtedmodel,itgavesomeoptimizationapproaches.Givennumericalexampleaboutthemodelcanshowthatthisdesignedgearwithsphericalinvolutetoothprofilecanachievefastandaccurateparametricmodelingandprovideafoundationfortoothcontactanalysis(TCA)indigitizeddesignandmanufacture.更多还原
简介:Toothextractionwasperformedin60casesunderdigitalacupointpressureanes-thesiawitharemarkablecurativeeffect.Thecurativeeffectwashigherforlooseteeth.Theeffectiveratewas100%.Thetoothextractionunderdigitalacupointpressureanesthesiahasmanyadvantages.Toothextractioncanbeperformedonlybypressingacertainacupointwithsafety,convenienceande-conomy.Themethodavoidsthesideeffectsofnarcoticandreducesthepatient’sfearofaninjectionofnarcotic.
简介:Themodulationandcontrolofgecko'sfootmovementswerestudiedelectrophysiologicallyinordertodesignthemotorcontrolsystemofagecko-mimicrobot.Inthisstudy(1)theanatomyoftheperipheralnervescontrollingthegecko'sfootmovementswasdetermined;(2)therelationshipbetweenthelimbnervesofthegeckoanditsfootmotorpatternswasstudied;(3)theafferentimpulsesofthenervesevokedbyrubbingthegecko'stoesandpalmwererecorded;(4)copyingthenaturalpatternsofmovementofthegecko'sfoot(abduction,adduction,flexion,andrevolution)anditslimbnervemodulationandcontrolmechanism,thenerveswerestimulatedundercomputercontrol,andtheresultsrecordedbyCCD.Resultssuggestthatgecko'sfootmovementscanbesuccessfullycontrolledbyartificialelectricalsignals.
简介:在土壤外壳开发的降雨事件运动的影响经由实验室实验和基于物理的水文学反应模拟被调查。流量和土壤水内容数据被分析以便在许多降水条件下面学习不同外壳的开发时期。当一个稳定的状态,能被雨点影响的一个扩大时期打破,被发现为外壳并且,随后存在时,结果证明显著地改变的外壳的形成玷污浸透的水力的电导率(K)和流量流量特征。在K的减少为下游动人的事件象86%一样高,并且72%为在上游动人的事件,说明降雨运动的方向比降雨紧张和持续时间在外壳形成上有更重要的影响。同样下游动人的降雨事件可以比那些移动有更大的效果在上游,在雨点影响前的一个depositional外壳的发展可以在决定最后的K价值起一个重要作用。
简介:Thisstudyhighlightsthejointeffectofearlypolymerizationshrinkageandlongtermmoisturediffusiononthebehavioroftherestoration-toothstructure.Theinterphasedebondingbetweenparticleandpolymerresinindentalcompositeistakenintoaccountbyintroducingthedamagevariable.Theidealizedmodelisdesignedandconstructedforrepresentingtherestorationtoothstructure,whichconsistsofenamel,dentin,compositeandinterphase,eachconsideredashomogenousmaterial.Thesimulationiscarriedoutusingthegeneral-purposefiniteelementsoftwarepackage,ABAQUSincorporatedwithausersubroutinefordefinitionofdamagedmaterialbehavior.TheinfluenceofYoung'smoduliofcompositeandinterphaseonstressanddisplacementisdiscussed.Thecompensatingeffectofwatersorptiononthepolymerizationshrinkageisexaminedwithandwithoutinvolvingdamageevolution.Acomparisonismadebetweentheinfluenceofhyper-,equi-andhypo-watersorption.Interfacialfailureinthespecificregionsaswellascuspalmovementhasbeenpredicated.Thedamageevolvingindentalcompositereducestherigidityofcomposite,thusinturnreducingconsequentstressandincreasingconsequentdisplacement.Thedevelopmentofstressesattherestoration-toothinterfacecanhaveadetrimentaleffectonthelongevityofarestoration.
简介:INTERNATIONALWOMEN'SMOVEMENTCOMESOFAGEATFWCWHughO'HaireTheFourthWorldConferenceonWomenwillberememberedlongandfarasthefinalste...
简介:DuringtheHercgnianmovcment,SouthChinadevelopedintothepeakperiodofPlatformstage,whichbecameapartofthcAncicntEastChinaPlatformReSion.However,thcreepisodicallyand1ocal-lyoccurredrelativclymobilcbeltsnamcdau1acogcnsduringthispcriod.Thcseaulacogens,suchasthemiddle-lowerYangtzerivcr,thePingxian-Lcping,the
简介:Background:TheFunctionalMovementScreen(FMS~(TM))hasbecomeincreasinglypopularforidentifyingfunctionallimitationsinbasicfunctionalmovements.ThisexploratoryanddescriptivestudywasundertakentoconfirmfeasibilityofperformingtheFMS~(TM)inolderactiveadults,assessprevalenceofasymmetriesandtoevaluatetherelationshipbetweenfunctionalmovementability,age,physicalactivitylevelsandbodymassindex(BMI).Methods:Thisisanobservationalstudy;97men(n=53)andwomen(n=44)betweentheagesof52and83participated.BMIwascomputedandself-reportedphysicalactivitylevelswereobtained.Subjectsweregroupedbyage(5-yearintervals),BMI(normal,over-weight,andobese)andsex.Eachparticipant'sperformanceontheFMS~(TM)wasdigitallyrecordedforlateranalysis.Results:Theyoungestagegroup(50–54years)scoredhighestinallseventestsandtheoldestagegroup(75+)scoredlowestinmostofthetestscomparedtoallotheragegroups.Thesubjectsinthe'normalweight'groupperformednodifferentthanthosewhowereinthe'overweight'group;bothgroupsperformedbetterthanthe'obese'group.Ofthe97participants54hadatleastoneasymmetry.ThepairwisecorrelationsbetweenthetotalFMS~(TM)scoreandage(r=-0.531),BMI(r=-0.270),andthemeasureofactivitylevel(r=0.287)weresignificant(p<0.01forall).Conclusion:FMS~(TM)scoresdeclinewithincreasedBMI,increasedage,anddecreasedactivitylevel.Thescreenidentifiesrangeofmotion-andstrength-relatedasymmetries.TheFMS~(TM)canbeusedtoassessfunctionallimitationsandasymmetries.FutureresearchshouldevaluateifahighertotalFMS~(TM)scoreisrelatedtofewerfallsorinjuriesintheolderpopulation.