简介：Thedragreductionofcompliantsurfaceisstudiedinashipmodeltank.There-sultsofthemeasureddragofaflatplatemodelshowthatthecompliantsurfaceiscapableofre-ducingdraginacertainrangeofspeeds,Themaximumdragreductionis15.7%whenthecom-pliantsurfaceismerelyontheonesideoftheplate.Theseresultshaveconfirmedthepredictedcharacteristicsofcompliantsurfaces.

简介：Inapreviouspaper,amethodhasbeendevelopedtostudythestabilitycharacteristicsoflaminarboundarylayersovercompliantwalls.Inthispaper,theeffectofdoublelayeredcompliantwallandKramertypecompliantwallondelayingthetransitionisinvestigated,anditisshownthattheredoesexistthepossibilitytode-laythetransitionbyapplyingsuchcompliantwalls.

简介：Thevelocityprofile,turbulenceintensityprofile,streakystructureandburstingfrequencyinturbulentboundarylayersoveraflatplatewithcompliantcoatingswereinvestigatedbyLaserDopplerAnemometryandcondi-tionalsamplingtechniques.Thisexperimentledtotheconclusionsthatinboundarylayerflowsonacompliantwall,ascomparedwiththatonarigidwall,theloglawregionwasextendedfurtherawayfromthewall,andthatthemaximumvalueofeachturbulenceintensityprofileinthenearwallregionwasreducedandtheburstingfrequencyobviouslydecreasedwiththecompliantcoatings.Onepointworthyofnoticewasthattheaboveresultswereverymuchlikethoseofpolymerdragreductionexperiments.

简介：Thestabilitycharacteristicsoflaminarboundarylayersovercompliantwallswasstudiedbythelineartheory.Unlikethepreviousauthors,thecoupledmotionofthefluidandsolidwasrequiredtosat-isfythecontinuityconditionsofboththevelocityandstressattheinterface.Resultsofcalculationsshowthatasthespeedratioordensityratioexceedsacertainthresholdvalue,thetwotypesofunstablewaveswillnolongerbedistinguishable,andthetangentialcomponentofthedisturbancestressisnolongernegligi-ble.Sotheneglectofit,asthepreviousauthorsdid,isunjustified.

简介：Theproblemoficeinducedvibrationiscommontooceanengineeringofcoldregioncountries.Tostudytheiceinducedvibrationofacompliantconicalstructure,aseriesofmodeltestshavebeenperformedandsomebreakthroughprogressesmade.Theicesheetbeforethecompliantconicalstructureisfoundtofailbytwo-timebreakinginthetests.Theprocessoftwo-timebreakingbehavesintwomodes,andthegeneralcontroloftheiceandstructuralconditionsdeterminethemodeinwhichtheiceforcewouldbehave.Twodynamiciceforcefunctionsareestablishedrespectivelyforthetwomodesoftwo-timebreakingprocessinthispaper.Thenumericalsimulationresultsareingoodagreementwiththemeasuredresults,indicatingthatthedynamiciceforcefunctionsgiveninthispapercanfullyreflecttherealsituationofthedynamiciceforceonacompliantconicalstructure.

简介：Purpose:Totesttheeffectivenessofsittingsurfaceswithvariedamountsofstabilityonmuscleactivityandenergyexpenditure.Methods:Usingawithin-participantsrepeatedmeasuresdesign,11healthyyoung-adultfemales(age=20.0±1.8years)weremeasuredusingindirectcalorimetrytoassessenergyexpenditure,andelectromyographytoassessmuscularactivationintrunkandlegmusculatureunder3differentsittingsurfaces:flat-firmsurface,air-filledcushion,andastabilityball.Datawereanalyzedusingrepeatedmeasuresanalysisofvariancewithfollow-uppairwisecontrastsusedtodeterminethespecificeffectsofsittingsurfaceonmuscleactivationandenergyexpenditure.Results:Significantlygreaterenergyexpenditurewasrecordedforthestabilityball(p=0.01)andthecushion(p=0.03)overtheflatsurface(10.4%and9.6%greater,respectively),withnodifferencesbetweentheballandthecushion.Boththeballandthecushionproducedhighertibialisanterioractivationovertheflatsurface(1.09and0.63root-mean-squaremillivolts(RMSmv),respectively),whilethestabilityballproducedhighersoleusactivityoverbothcushionandflatsurfaces(3.97and4.24RMSmv,respectively).Additionally,thecushionelicitedhigheradductorlongusactivityovertheballandflatsurfaces(1.76and1.81RMSmv,respectively),butnotrunkmusculaturedifferenceswererevealed.Conclusion:Compliantsurfacesresultedinhigherlevelsofmuscularactivationinthelowerextremitiesfacilitatingincreasedcaloricexpenditure.Giventheincreasingtrendsinsedentarycareersandtheincreasesinobesity,thisisanimportantfindingtovalidatethemeritsofactivesittingfacilitatingincreasedcaloricexpenditureandmuscleactivation.

简介：我们涉及象血那样的能量守恒定律建模uidows的一个维的夸张系统的推导和分析嗷通过顺从的axisymmetric容器。导出的早模型与措施来源术语是nonconservative或nonhomogeneous，它无穷地被赋予以一些Riemann数据的许多Riemann解决方案。在这份报纸，我们导出保守、同类的一个一个维的夸张系统。而且，在那里存在为有任意地大的Riemann数据的二个容器的Riemann问题的一个唯一的全球Riemann解决方案，在一个自然稳定性熵标准下面。Riemann答案可以为一些盒子由四个波浪组成。系统能也作为严格的hyperbolicity为失败的3脳3系统被写，站的波浪能与零个特征值被认为是相应于第二个家庭的接触断绝。

简介：从在无限的声学的媒介沉浸的有限的圆柱的壳的健全放射上的多重顺从的层的效果被学习。转移矩阵在多层的system.With的每个邻近的接口根据连续边界条件被导出壳理论和声学的波浪方程，理论模型被开发估计声音的特征放射。声学的放射力量减小的数量作为波浪速度或顺从的层减少的密度增加的数字计算结果表演，和使用的多层的系统能比相应一致单身者在噪音减小上是更有效的层。

简介：Syntheticdryadhesivesinspiredbythenano-andmicro-scalehairsfoundonthefeetofgeckosandsomespidershavebeendevelopedforalmostadecade.Elastomericsinglelevelmicro-scalemushroomshapedfibresarecurrentlyabletofunctionevenbetterthannaturaldryadhesivesonsmoothsurfacesundernormalloading.However,theadhesionofthesesinglelevelsyntheticdryadhesivesonroughsurfacesisstillnotoptimalbecauseofthereducedcontactsurfacearea.Innature,contactareaismaximizedbyhierarchicallystructuringdifferentscalesoffibrescapableofconformingsurfaceroughness.Inthispaper,weadaptthenature’ssolutionaridproposeanoveldual-levelhierarchicaladhesivedesignusingPolydimethylsiloxane(PDMS),whichistestedunderpeelloadingatdifferentorientations.Anegativemacro-scalemoldismanufacturedbyusingalasercuttertodefineholesinaPoly(methylmethacrylate)(PMMA)plate.AftercastingPDMSmacro-scalefibresbyusingtheobtainedPMMAmold,apreviouslypreparedmicro-fibreadhesiveisbondedtothemacro-scalefibresubstrate.Oncethebondingpolymeriscured,themicro-fibreadhesiveiscuttoformmacroscalemushroomcaps.Eachmacro-fibreoftheresultinghierarchicaladhesiveisabletoconformtoloadsappliedindifferentdirections.Thedual-levelstructureenhancesthepeelstrengthonsmoothsurfacescomparedtoasingle-leveldryadhesive,butalsoweakenstheshearstrengthoftheadhesiveforagivenareaincontact.Theadhesiveappearstobeveryperformancesensitivetothespecificsizeofthefibretips,andexperimentsindicatethatdesigninghierarchicalstructuresisnotassimpleasplacingmultiplescalesoffibresontopofoneanother,butcanrequiresignificantdesignoptimizationtoenhancethecontactmechanicsandadhesionstrength.

简介：

简介：Climbingrobotsareofpotentialuseforsurveillance,inspectionandexplorationindifferentenvironments.Inparticular,theuseofclimbingrobotsforspaceexplorationcanallowscientiststoexploreenvironmentstoochallengingfortraditionalwheeleddesigns.Toadheretosurfaces,biomimeticdryadhesivesbasedongeckofeethavebeenproposed.Thesebiomimeticdryadhesivesworkbyusingmulti-scalecompliantmechanismstomakeintimatecontactwithdifferentsurfacesandadherebyusingVanderWaalsforces.Fabricationoftheseadhesiveshasfrequentlybeenchallenginghowever,duetothedifficultyincombiningmacro,microandnanoscalecompliance.Wepresentanallpolymerfootdesignforusewithahexapodclimbingrobotandafabricationmethodtoimprovereliabilityandyield.Ahighstrength,low-modulussilicone,TC-5005,isusedtoformthefootbaseandmicroscalefibresinonepiecebyusingatwopartmold.Amacroscalefootdesignisproducedusinga3Dprintertoproduceabasemold,whilelithographicdefinitionofmicroscalefibresinathickphotoresistformsthe‘hairs’ofthepolymerfoot.Theadhesionofthesiliconefibresbythemselvesorattachedtothemacrofootisexaminedtodeterminebeststrategiesforplacementandremovaloffeettomaximizeadhesion.Resultsdemonstratethesuccessfulintegrationofmicroandmacrocompliantfeetforuseinclimbingonavarietyofsurfaces.

简介：AbstractBackground:Nipple discharge cytology is a simple non-invasive method that may provide valuable information for detecting underlying malignancy. Several studies have investigated the diagnostic value of cytology in breast cancer patients with pathological nipple discharge, but the results have been highly variable. Herein we presented a systematic review and meta-analysis of published studies pertaining to the diagnostic capacity of nipple discharge cytology in patients with breast cancer.Methods:A systematic literature search was performed (Medline/PubMed, Embase, Cochrane Library databases, and Google Scholar) to identify studies that investigated the diagnostic capacity of cytology with regard to breast cancer in patients with pathologic nipple discharge. Two independent researchers identified articles that assessed the sensitivity and specificity of cytological evaluation for breast cancer detection in patients with pathologic nipple discharge published between January 2000 and October 2018. Articles were only included in the meta-analysis if they met predetermined criteria. The characteristics of each study and the data they yielded were summarized. Quality assessment of all articles included was performed using the Methodological Index for Non-randomized Studies Criteria (MINORS) and the Quality Assessment of Diagnostic Accuracy Study 2 (QUADAS-2). Heterogeneity was tested via Cochran Q test and the I2 statistic using Stata 12.0 and Meta-DiSc 1.4 software, and meta-analysis was performed.Results:A total of 286 articles were identified, of which 12 articles including a total of 1476 patients were deemed eligible for inclusion in the meta-analysis. A random-effects model assessing the capacity of nipple discharge cytology to predict breast cancer yielded pooled sensitivity 63% (95% confidence interval [CI]: 53%-72%), specificity 95% (95% CI: 87%-98%), positive likelihood ratio 12.35 (95% CI: 4.87-31.34), and negative likelihood ratio 0.39 (95% CI: 0.30-0.50). The diagnostic odds ratio was 31.88 (95% CI: 11.30-89.98). The area under the summary receiver operating characteristic curve was 0.79 (95% CI: 0.75-0.82). Conclusion: The current meta-analysis suggests that nipple discharge cytology is a useful diagnostic modality for detection of breast cancer in patients with pathological nipple discharge, with moderate sensitivity and high specificity.

简介：AIMTo调查锰superoxidedismutase(MnSOD)的协会有糖尿病的retinopathy(医生)的Val16Ala多型性.METHODSPubMed，Embase，中国知识基础结构，和Wanfang数据库被寻找。分享的机会比率(ORs)和95%信心间隔(CI)被计算评估协会的力量。亚群，敏感，和累积分析被执行。出版偏爱也是analyzed.RESULTSEight研究在分享的分析被包括。MnSODVal16Ala多型性在主导的模型下面与医生的风险被联系(OR=0.66，95%CI=0.48-0.91，P<0.0001)，这结果被表明在累积分析相对稳定。没有重要出版偏爱被发现。这多型性也在主导的模型下面在白种人与医生的风险被联系(OR=0.64，95%CI=0.42-0.97，P=0.04，)并且在在后退的模型下面的亚洲人(OR=0.31，95%CI=0.11-0.88，P=0.03).CONCLUSIONThese调查结果建议MnSODVal16Ala多型性是为医生的一个风险因素，并且更多的注意竟然对这些危险性基因的搬运人被给予。