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简介：ItisaclassicalresultofBernsteinthatthesequenceofLagrangeinterpolationpolynomialsto|x|atequallyspacednodesin[-1,1]divergeseverywhere,exceptatzeroandtheend-points.InthispaperweshowthatthesequenceofLagrangeinterpolationpolynomialscorrespondingtothefunctionswhichpossessbettersmoothnessonequidistantnodesin[-1,1]stilldivergeseverywhereintheintervalexceptatzeroandtheend-points.

简介：PropertiesofLebesguefunctionforLagrangeinterpolationonequidistantnodesareinvestigated.ItisprovedthatLebesguefunctioncanbeformulatedbothintermsofahypergeometricfunction2F1andJacobipolynomials.Moreover,anintegralexpressionofLebesguefunctionisalsoobtainedandtheasymptoticbehaviorofLebesgueconstantisstudied.

简介：Signalsarriveoutofphaseattheintendedreceiverfromcollaborativebeamforming（CB）nodesduetotheinstabilityintheoutputfrequencysignalsoftheuniversalsoftwareradioperipheral’s（USRP）localoscillator（LO）.Thesenodesincludingthetargetmustsynchronizetheiroscillatorfrequenciesforcoherentsignalreception.Inordertodothis,frequenciesandphasesofthesignalsshouldbeestimatedinsoftwaredefinedradio（SDR）andsmoothenwithnonlinearfilterssuchastheextendedKalmanfilter（EKF）.TheprocessnoiseparametersoftheNIUSRP-2920nodeswillhavetobecalculatedandusedwiththeEKFprocessnoisecovariancematrix.Thesenodesaregreencommunicationhardwaredeviceswheremostofthehardwareunitsarenowsoftwaredefined.ThisarticleusesthedirectspectrummethodtoobtainthephasenoisevaluesatvariousfrequencyoffsetsoftheNIUSRP-2920inordertocalculatethepowerspectraldensityoffractionalfrequencyfluctuation.Byapplyingthepower-lawnoisemodeltothisobtainedvalue,thegeneratedwhitefrequencynoiseandrandomwalkfrequencynoisevaluesareq1=1.93×10-21andq2=5.86×10-18,respectively.

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简介：LetFF_vbethesetoffaultynodesinann-dimensionalfoldedhypercubeFQ_nwith|FF_v|≤n-1andallfaultyverticesarenotadjacenttothesamevertex.Inthispaper,weshowthatifn≥4,theneveryedgeofFQn-FF_vliesonafault-freecycleofeveryevenlengthfrom6to2~n-2|FF_v|.

简介：S.M.LozinskiiprovedtheexactconvergencerateatthezeroofLagrangeinterpolationpolynomialsto|x|basedonequidistantnodesin[-1,1].In2000,M.RevergeneralizedS.M.Lozinskii'sresultto|x|α(0≤α≤1).Inthispaperwewillpresenttheexactrateofconvergenceatthepointzerofortheinterpolantsof|x|α(1＜α＜2)..

简介：Inthispaper,weinvestigatethenegativeextremumsoffundamentalfunctionsofLagrangeinterpolationbasedonChebyshevnodes.Moreover,weestablishsomecompanionresultstothetheoremofJ.Szabadosonthepositiveextremum.

简介：A统一了posteriori错误分析被开发了在[18,2123]分析有限元素错误在一个通用房顶下面的posteriori。这份报纸与挂为本地人被要求的节点贡献有限元素网孔精制网孔。进三角形和平行四边形和他们的联合的不规则的三角测量与遵守中间的nonconforming被认为有限元素方法的二维的1--依照或由报纸命名，Q[1]，Crouzeix-Raviart，为泊松的火腿Rannacher-Turek，和其它，司烧并且海军打敢椠?桴?慦業祬眠祡吗？

简介：Objective:Survivalbenefitofadjuvantchemotherapy(AC)ofpatientswithintrapulmonarylymphnode(IPLN)metastasis(level12-14)needsinvestigation.WeevaluatedtheimpactofAConpatientswhosemetastaticnodeswerelimitedtointrapulmonarylevelsaftersystematicdissectionofN1nodes.Methods:First,155consectivecasesoflungcancerconfirmedaspathologicN1werecollectedandevaluated.PatientsreceivedsystematicdissectionofN2andN1nodes.ForpatientswithIPLNmetastasis,survivaloutcomeswerecomparedbetweenthosereceivingACandthosenotreceivingAC.Results:Inthisgroup,112cases(72.3%)hadIPLNmetastasisand55cases(35.5%)hadN1involvementlimitedtolevel13-14withoutfurtherdiseasespreadtohigherlevels.PatientswithIPLNinvolvementhadabetterprognosisthanthatofpatientswithhilar-interlobarinvolvement.FortheintrapulmonaryN1group(level12-14-positive,level10-11-negativeorunknown,n=112),nosurvivalbenefitwasfoundbetweentheACgroupandnonACgroup[5-yearoverallsurvival(OS):54.6±1.6vs.50.4±2.4months,P=0.177].However,76of112casesforwhomharvestingoflevel-10andlevel-11nodeswasdonedidnotshowcancerinvolvementinpathologyreports(level12-14-positive,level10-11bothnegative),oncologicoutcomewasbetterforpatientsreceivingACthanthosenotreceivingACinthissubgroup(5-yearOS:57.3±1.5vs.47.1±3.2months,P=0.002).Conclusions:OncologicoutcomemaybeimprovedbyACforpatientswithinvolvementofN1nodeslimitedtointrapulmonarylevelsaftercompleteexaminationofN1nodes.

简介：Inthispaperwestudytheconvergenceofadaptivefiniteelementmethodsforthegeneralnon-affineequivalentquadrilateralandhexahedralelementson1-irregularmesheswithhangingnodes.Basedonseveralbasicingredients,suchasquasi-orthogonality,estimatorreductionandD(o|¨)flermarkingstrategy,convergenceoftheadaptivefiniteelementmethodsforthegeneralsecond-orderellipticpartialequationsisproved.OuranalysisiseffectiveforallconformingQ_melementswhichcoversboththetwo-andthree-dimensionalcasesinaunifiedfashion.

简介：Inthispaper,anopportunisticcooperativeadhocsensornetworkwithrandomlylocatednodesisanalyzed.Therandomnessofnodes'locationsiscapturedbyahomogeneousPoissonpointprocess.Theeffectofimperfectinterferencecancellationisalsotakenintoaccountintheanalysis.Basedonthetheoryofstochasticgeometry,outageprobabilityandcooperativegainarederived.Itisdemonstratedthatexplicitperformancegaincanbeachievedthroughcooperation.Theanalysesarecorroboratedbyextensivesimulationresultsandtheanalyticalresultscanthusserveasaguidelineforwirelesssensornetworkdesign.

简介：在由nonoscillatory节点组成的复杂网络的自我支撑的摆动在多样的自然、社会的系统吸引了长期的兴趣。我们在由易兴奋的节点组成的随机的网络学习自我支撑的周期的摆动。我们由使用驾驶方法的主导的阶段进展揭示内在的动态结构。摆动来源和波浪繁殖路径能经由揭示的动态结构清楚地被说明。当时，我们能基于我们的理解与令人惊讶地高的效率控制摆动。

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简介：InthispapersufficientconditionsformeanconvergenceandrateofconvergenceofHermite-FejertypeinterpolationintheLpnormonanarbitrarysystemofnodesarepresented.

简介：最近，Brutman和Passow认为Newman类型合理插值是to|x|由对称的节点的任意的集合导致了在[-1,1]并且给了近似错误的一般评价。由他们的方法，一个人能为一些特殊节点建立近似的准确顺序。在我们考虑插值节点是第二种类型的零个Chebyshev多项式并且在这种情况中证明那的特殊情况的现在的纸，近似的准确顺序是O(1/(nlnn))。

简介：Objectives:ToexploretheprognosticrelevanceofthenumberandratioofmetastaticlymphnodesinresectedCarcinomaoftheampullaofVater(CAV).Methods:Theclinicaldataof155patientswhounderwentpancreaticoduodenectomy(PD)forcanceroftheampullaofVaterbetweenJanuary1990andDecember2010wereretrospectivelyanalyzed.KaplanMeiermethodwasusedinsurvivalanalysisandLogrankmethodincomparison.MultivariateanalysiswasperformedusingCoxproportionalhazardsmodel.Results:Amongthese155patients,thein-hospitalmortalityratewas4.5%,lymphnodepositivediseasewas21.3%,andthe5-yearsurvivalratewas51.6%.Patientswithalymphnoderatio(LNR)>20%weremorelikelytohavetumordifferentiation,depthofduodenalinvolvement,depthofpancreaticinvasion,T-stageandTNM-Stage.ThenumberofthemetastaticlymphnodesisimportantprognosticfactorsoftheCAV.Univariateanalysisshowedthatthefactorsassociatedwiththeprognosisincludedtumorsize(P=0.036),tumordifferentiation(P=0.019),LNR(P=0.032),numberofmetastaticlymphnodes(P=0.024),lymphnodemetastasis(P=0.03),depthofpancreaticinvasion(P=0.001),T-stage(P=0.002),TNMstage(P=0.001),elevatedCA19-9(P=0.000),andjaundice(P=0.021).Multivariateanalysisshowedthatthefactorsassociatedwiththeprognosiswerethenumberofmetastaticlymphnodes(P=0.032;RR:1.283;95%CI:1.022-1.611),tumorsize(P=0.043;RR:1.736;95%CI:1.017-2.963),andelevatedCA19-9(P=0.003;RR:3.247;95%CI:1.504-7.010).Conclusions:LNRisausefulfactorforpredictingtheprognosisoftheradicaltreatmentforCAV,whereasthenumberofmetastaticlymphnodesisthemostimportantfactor.Furtherresearchonthelocations,number,andLNRwillbeclinicallymeaningfultoimprovesurvivalinpatientswithCAV.

简介：AbstractBackground:The symptomatic bradyarrhythmia is Class I indication for pacing therapy which is not a radical cure. The present study aimed to assess the feasibility and to present the initial results of the restricted ablation of the parasympathetic innervation surrounding sinus and atrioventricular (AV) nodes for treating patients with bradyarrhythmia.Methods:A total of 13 patients with cardiogenic syncope were included from May 2008 to June 2015. Under the guidance of fluoroscopy and /or three-dimensional geometry by 64-slice spiral computed tomography, atrial activation sequence in sinus rhythm was mapped. Chamber geometry was reconstructed manually or automatically using the Niobe II magnetic navigation system integrated with the CARTO-remote magnetic technology (RMT) system. Cardioneuroablation was targeted at the high-amplitude fractionated electrograms surrounding the regions of His bundle and the site with the earliest activation in sinus rhythm. Areas surrounding the sinus node, AV node, and the phrenic nerve were avoided.Results:Thirteen patients completed the studies. Ablation was successfully performed in 12 patients and failed in one. The high-frequency potential was recorded in atrial electrograms surrounding the sinus or AV nodes in all the patients and disappeared in 15 s after radiofrequency applications. The vagal reaction was observed before the improvement of the sinus and AV node function. No complications occurred during the procedures. Patients were followed up for a mean of 13.0 ± 5.9 months. During the follow up ten patients remained free of symptoms, and two patients had a permanent cardiac pacemaker implanted due to spontaneous recurrence of syncope. The heart rate of post-ablation was higher than pre-ablation (69.0 ± 11.0 vs. 49.0 ± 10.0 beats/min, t = 4.56, P = 0.008). The sinus node recovery time, Wenckebach block point, and atrium-His bundle interval were significantly shorter after ablation (1386.0 ± 165.0 vs. 921.0 ± 64.0 ms, t = 7.45, P = 0.002; 590.0 ± 96.0 vs. 464.0 ± 39.0 ms, t = 2.38, P = 0.023; 106.0 ± 5.0 vs. 90.0 ± 12.0 ms, t = 9.80, P = 0.013 before and after ablation procedure, respectively).Conclusions:Ablation of sinoatrial and AV nodal peripheral fibrillar myocardium electrical activity might provide a new treatment to ameliorate paroxysmal sinus node dysfunction, high degree AV block, and vagal-mediated syncope.

简介：Objective:TostudyexplorestheeffectofHLEConthesecretedproteinsofepithelialovariancancer(EOC)cells(SKOV3-PM4)withdirectionalhighlylymphaticmetastasis.Methods:Supernatantsoffourgroupsofculturedcells,namely,SKOV3(A),SKOV3+HLEC(B),SKOV3-PM4(C),SKOV3-PM4+HLEC(D),werecollected,andtheirproteinsweredetectedbyantibodyarraysandiTRAQ-2D-LC-MALDITOF/TOF/MS.SignificantlydifferentialproteinswerefurtheranalyzedviabioinformaticsandvalidatedinhumanserumsandcellmediaviaELISA.Results:ResultsofantibodyarraysandmassspectrometrydemonstratedthatGRNandVEGFAwereupregulatedingroupC(comparedwithgroupA),whereasIGFBP7andSPARCweredownregulatedingroupD(comparedwithgroupC).ComprehensivebioinformaticsanalysisresultsshowedthatIGFBP7andVEGFAwerecloselylinkedtoeachother.FurthervalidationwithserumsshowedstatisticalsignificanceinVEGFAandIGFBP7levelsamonggroupsofpatientswithovariancancers,benigntumors,andcontrolgroups.Twoproteinswereupegulatedinthefirstgroup.VEGFAinthecontrolgroupwasdownregulated.ForIGFBP,upregulationinthecontrolgroupanddown-regulationinthefirstgroupwerealsoobserved.Conclusion:TheHLECmicroenvironmentiscloselyassociatedwithdirectionalmetastasistolymphnodesandwithdifferentialproteinsincludingcellstromalproteinsandadhesionfactors.TheupregulationofVEGFAandGRNandthedownregulationofSPARCandIGFBP7arecloselyassociatedwithdirectionalmetastasistolymphnodesinEOCcells.

简介：淋巴的系统在在人和动物模型装有免疫力的回答到外国抗原和肿瘤是重要的。肝生产大量淋巴，和它的淋巴的系统被划分成三个主要部件：门，sublobular和表面的淋巴管。尽管老鼠是最通常使用的实验室动物，对解剖地点的详细描述和排干肝的淋巴节点(行)的功能是令人惊讶地不在的。在这研究，我们发现门和邻近老鼠肝的腹的行在5-8min以内与Evans蓝色被染色。从肝的积极房间也排干进二上述的行的提高的绿荧光蛋白质(EGFP)。这些数据显示门和腹的行排干鼠标肝。识别的排干肝的行的Lymphadenectomy导致了肝炎B在免疫能力的老鼠的病毒(HBV)坚持与假冒的组相比。另外，CD8+T房间的频率和树枝状的房间(DC)在HBVplasmid的水动力学注射以后在排干肝的行显著地增加了。在HBV注射plasmid的老鼠的排干肝的行房间也在vitro与recombinant肝炎B核心抗原响应刺激显示出重要抗原特定的增长。进Rag1−/−老鼠的这些房间的采纳转移在uninjected老鼠与排干肝的行房间相比在肝炎B表面抗原(HBsAg)的浆液集中导致了减小。总的来说我们的数据描绘排干肝的行并且提供排干肝的行导致为HBV负责的anti-HBV-specific免疫者回答的证据清理。