简介：Recentstudieshaverevealedthatthepropertyofdrugismainlyassociatedwiththebody'ssubstanceandenergyme-tabolism.ThepresentstudyaimedtoevaluatethedrugpropertyofPoria,calledFuling(FL)intraditionalChinesemedicine(TCM),intermsofitseffectsonthesubstanceandenergymetabolisminratmodelsofcold-deficiencyandheat-deficiencysyndromes,comparedwithAconitiLateralisRadixPraeparaia,calledFuzi(FZ)inTCM,withhotproperty,andAnemarrhenaeRhizoma,calledZhimu(ZM)inTCM,withcoldproperty,asreferencedrugs,respectively.Theappearancescore,toeandrectaltemperaturesoftheanimalstreatedwereassessedatdifferenttimepoints.Severalindicesinvivocorrelatedwithsubstanceandenergymetabolism(glucokinas,phosphoglyceratekinase,cytochromecreductase,cytochromecoxydase,andNa^+-K^+-ATPase),endocrinesystem(triiodothyronine,thyroxine,and17-hydroxycorticosteroid),nervoussystem(acetylcholinesterase),andcyclicnucleotidesystemweredetermined.Thechangesinappearancescoreandindicesinvivosuggestedthesuccessfulestablishmentofcold-deficiencyandheat-deficiencysyndromemodels.FZreversedthedecreasedlevelsofindices(substanceandenergymetabolismandendocrinesystem)andalleviatedthesyndromeofcold-deficiencymodel,andZMshowedobviouslytherapeuticeffectonheat-deficiencysyndrome(appearancescore,substanceandenergymetabolism,andendocrinesystem).FLcouldalleviatecold-deficiencysyndromeandraisethedecreasedlevelsofglucokinas,phosphoglyceratekinase,cytochromecreductaseandtriiodothyronineincold-deficiencymodel,buthadnosignificanteffectonheat-deficiencysyndrome.DrugpropertyofFLwasinferredastrendingto"flatandwarm",whichstillneedfurtherstudy.Itwasadvisabletoadoptbothcold-deficiencyandheat-deficiencymodelstostudythedrugswith"flat"property.

简介：Waardenburgsyndromeisararediseasecharacterizedbysensorineuraldeafnessinassociationwithpigmentarydefects.Dependingonadditionalsymptoms,WShavebeenclassifiedintofourtypes.Waardenburgsyndrometype4,alsocalledasWaardenburgShahSyndromeisaveryrarecongenitaldisorderwithastoundingvariableclinicalexpression,characterizedbypigmentaryabnormalitiesofthehair(Awhiteforelockofhair,prematuregraying)andpigmentarychangesoftheirissuchasheterochromiaorhomochromiairides,sensorineuraldeafnessandHirschsprungdisease.ThreegeneshavebeenbestowedsofarinconsociationwithEDNRB,EDN3,andSOX10genes.ThepatternofinheritanceismultifariouswiththeSOX10mutationaffiliationwithautosomaldominantinheritancewhereastheEDNRBandEDN3genesarepasseddowninanautosomallyrecessivepattern.

简介：总结1例Kasabach-Merrittsyndrome患儿的护理体会。护理要点:重视出血的观察及护理,做好特殊药物的用药护理,加强介入治疗及手术后护理。经治疗和护理,患儿康复出院。

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简介：BackgroundThrombocytopeniaisacommoncomplicationofIABP.Untilnow,thereisnounifiedconclusionsabouttheincidence,characteristics,riskfactorsandtheprognosisofIABPrelatedthrombocytopenia.MethodsInthisstudy,thedataofpatientswithACSundergoingPCIandIABPwereretrospectivelyanalyzed.Allenrolledpatientsweredividedintothrombocytopeniagroupandnon-thrombocytopeniagroupaccordingtotheoccurrenceofthrombocytopeniaafterinsertionofIABP.Thebaselinedataofthetwogroupswerecompared,andthepossibleriskfactorsofthrombocytopeniaandtheirimpactonprognosiswereanalyzedbychi-squaretestandlogisticregressionanalysis.ResultsSixty-twopatientswereenrolledinthisstudy.TherateofIABPassociatedthrombocytopeniawas25.8%(16/62)ofallpatients.OlderagewasanindependentriskfactorofIABPassociatedthrombocytopenia(OR:3.625;95%confidenceinterval:1.016-12.935;P=0.047).TheincidenceofTIMIbleedingeventswashigherinthrombocytopeniagroup[75.0%(12/16)vs.43.5%(20/46),P=0.042].Therateofin-hospitaldeathwassimilarbetweenthetwogroups[18.8%(3/16)vs.17.4%(8/46),P=1.0].ConclusionIABPassociatedthrombocytopeniaoccursin25.8%ofpatientswithACSundergoingPCIandcorrelateswithincreasedTIMIbleedingevents.OlderagemaypredictIABPassociatedthrombocytopenia.

简介：Acuteaorticsyndromeincludesclassicaorticdissection,aorticintramuralhematoma,andpenetratingatheroscleroticulcer–agroupofconditionsthataredefinedbytheirdynamicevolutionandsimilarclinicalmanifestation.Accuratediagnosisandprompttreatmentareessentialasalltheaforementionedconditionsareasignificantthreattoapatient’slife.However,acuteaorticsyndromeandespeciallyaorticintramuralhematomamaybechallengingdiagnosticproblems.Intravascularultrasoundimagingisadiagnosticmethodthatcanbeusefulformorethoroughevaluationoftheaorticlesionandcanparticularlyaidindiscerningthedifferentformsofacuteaorticsyndrome.Wepresentacaseofapatientwithaorticintramuralhematomathatwasmissedbyconventionalimagingstudiesbutwassuccessfullyvisualizedwithintravascularultrasoundimaging.

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