简介:目的:照观察针药结合与单纯西药治疗中风后抑郁症(PSD)的疗效及不良反应。方法:采用开放性对照研究方法,将93例抑郁症患者随机分为三组,针药组30例、百忧解A组30例、百忧解B组33例。针药组口服百忧解20mg/d并加以针刺,百忧解A组口服百忧解20mg/d,百忧解B组口服百忧解20~40mg/d;三组治疗时间均为42d,以汉密尔顿抑郁量表(HAMD)及副反应观察量表(TESS)分别观察三组的疗效及不良反应。结果:针药组有效率为86.7%,百忧解A组为63.3%,百忧解B组为87.9%,针药组疗效优于百忧解A组,与百忧解B组疗效差异无统计学意义(P〉0.05),但药物不良反应发生率百忧解B组高于针药组。结论:药并用是脑卒中后抑郁症的一种疗效确切且副反应少的治疗方法。
简介:ObjectivesToinvestthesuccessprocedure,immediateoutcomeafterprocedure,therateofmainadversecardiaceventsafterprocedureandrestenosisafterstentplacementinsmallcoronaryvessels.Methods290patientswithselectedoremergencystentimplantationinsmallvesselsfromApril,1997toMarch,2002.Total299vessels,304lesionsand316stentswerestatisted.Thesuccesssrateofprocedure,immediateoutcomeafterprocedure,therateofmainadversecardiaceventsafterprocedureandrestenosisafterstentplacementinsmallcoronaryvesselswereassessed.Thepatientswerefollowedup1monthto4years.Re-catheterangiographyweredonein122/290patients.ResultsThenarrowrateoflesiondroppedfrom89%±12%beforeprocedureto5%±5%afterprocedure(diameter).202patientswerefollowedup1month(69.7%).197/202casesweresurvival.5/202casesdiedin3hrsto7days.2/5casesdiedofpersistenthypotensionafterprocedure.1/5casediedofacuteleftheartfailure.2/5casesdiedofsuddendeath.180caseswerefollowedup5monthsto4years.Thenon-eventsurvival(NES)ratewas73.3%(132/180).There-angiographyweredonein122cases.Restenosishappenedin39cases(30.3%).37patientsrepeatedPCI.2patientswenttoCABG.2casesgotanginarecurrenceandwereprovedsecondtimerestenosisbyre-angiography.ThethirdtimePCIwasdonein1patient.TheotherpatientswenttoCABG.1casediedofchronicheartfailureafter2years.1casesufferedacutemyocardialinfarctiononarterystentimplanted.ConclusionsTherearehighsuccessrateofprocedureandperfectimmediateoutcomeinstentplacementinsmallvessels.Mainadversecardiaceventsdidnotincreased.Non-eventsurvialwassatisfiedinlongtermfollow-up.Restenosisratewasshowedslightlyhigherthantheoneofmainvessels.
简介:ObjectiveTocomparedifferenttreatmentprotocolsforsuddendeafness(SD),forthepurposeofidentifyinganappropriateapproachtoSD.MethodsAtotalof104patientswithdiagnosisofsuddenhearinglosstreatedfromJan2006toDecember2008wereincludedinthisstudy,ofwhich31receivedthetypicalpharmaceuticaltreatment(groupⅠ),40receivedthetypicalpharmaceuticaltreatmentpluspolarizedliquid(GroupⅡ)and33receivedthehyperbaricoxygeninadditiontothetreatmentincludedinGroupⅡ(GroupⅢ).ResultsThetotalimprovementrate(67.74%,62.50%and75.76%forGroupsⅠ,ⅡandⅢrespectively)wasnotstatisticallydifferentbetweenthethreegroups(P>0.05).ConclusionThethreetreatmentprotocolsaresimilarwhenjudgedbythetreatmentoutcomesinSD,neitherbeingsuperiortotheothers.Thetwoimportantfactorsthatappeartoinfluencetreatmentoutcomesaretheaudiogrampatternanddurationofhearinglossbeforeseekingtreatment.Patientswithupslopingorpeak-typeaudiogramsandtreatedwithin7daysfromtheonsethavebetterprognosisthanothers.
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简介:Inthispaper,amathematicalmodelfortopologyoptimizationoftrussstructureswithconstraintsofdisplacementandsystemreliabilityundermultipleloadingcasesisconstructed.Inordertoavoidthedifficultyofcomputingthestructure’ssystemreliability,asolvingapproachispresentedinwhichthefailureprobabilityofsystemisdividedintothesumofallbars’failureprobabilitybymeansofreliabilitydistribution.Inaddition,bydrawingintothereliabilitysafetyfactorandthefundamen-talrelationshipinstructuralmechanics,allprobabilityconstraintsofdisplacementandstressareequiv-alentlydisplayedasconventionalformandlinearfunctionofthedesignvariables.Theoptimizationproblemwithmultipleconstraintsistreatedbythecompactconstrainttacticsandissolvedbytheim-provedsimplexmethod.Theexamplesshowthattheapproachproposedinthispaperisfeasibleandef-ficient.
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简介:76patientsofimpotencewererandomlydividedintotwogroups.Of28casesinacupuncturegroup,18werecured,5effectiveand5ineffective.Of48casesinacupunctureplusacu-point-injectiongroup,41werecured,5effectiveand2ineffective.Thecurativeeffectintheacupunc-tureplusacupoint-injeetiongroupwassuperiortothatintheacupuncturegroup(P<0.01).
简介:NinetycasesofscapulohumeralperiarthritisweretreatedbyelectroacupunctureplusTuinaandtheeffectiveratewas94.4%.Theeffectiveratewas81.9%inthecontrolgroup(treatedbyFrozenShoulderDecoctionaddedbyotherherbaldrugs)of83cases.Theresultindicatedthatthetreatmentsofthetwogroupswereeffective,butthetherapeuticeffectofthetreatmentgroupwasbetterthanthatofthecontrolgroup.Inthetreatmentgroup,thecureratewashigher,thedurationoftreatmentwasshorterandthesequelaeofconglutinationandrigidityoftheshoulderjoint,muscularatrophyandsoonwerereduced.
简介:Basedontheprincipleformulaforthefour-componentstrainmeters,wecandirectlyobtainthespecificplanestrain,shearstrainandazimuthalangleoftheprincipalstrain,andthemaximumandminimumprincipalstrainscalculatedafterwardsaretheindirectresult.TheproblemsofpracticalityofthesensitivitycoefficientsAandBofplanestrainandshearstrainarethendiscussed.Basedonthisidea,weanalyzedtheobservationdataofseveralfourcomponentboreholestrainmetersneartheepicenteroftheYiliangMS5.7earthquakein2012andtheLudianMS6.5earthquakein2014intheZhaotongarea,YunnanProvince.Theresultsshowthattheanalysisbasedontheperspectiveofplanestrainandshearstrainhasanobviouslybettereffectthanthatbasedonthecomponentreadings,andcandirectlypeelofftherespectiveabnormalityoftheplanestrainandshearstrain.Inaddition,thecorrelationcoefficientcurvesbetweenmeasureddataoftwoplanestrainsshowsignificantanomalieswhichoftenoccurseveraldaysbeforeandduringtheearthquake.
简介:Objective:Toobservethetherapeuticeffectofround-sharpneedleforprolapseoflumbarintervertebraldisc.Methods:Atotalof80casesoflumbarintervertebraldiscprolapseweretreatedbypuncturingQihaishu(气海俞BL24),Guanyuanshu(关元俞BL26),etc.,withround-sharpneedle,onceeveryweek,continuouslyfor4sessions.Results:Afterthetreatment,ofthe80cases,56(70%)werecured,16(20%)improved,and8(10)%)failed,withaneffectiverateof90%.Conclusion:Round-sharpneedleworkswellinthetreatmentofprolapseoflumbarintervertebraldisc.
简介:Ashipoints,movablecuppingandtractionwereemployedtotreat120casesofprolapaseoflumberintervertebraldisk,andthetotaleffectiveratewas95.6%.
简介:AbstractPurpose:The pathogenesis of gastrinomas is largely unknown, and there is a lack of reliable genetic determinants that are useful to distinguish malignant and benign forms of this tumor or predict the prognosis of patients with this disease. Loss of heterozygosity (LOH) on chromosome 3p is reported to occur in pancreatic neuroendocrine tumors (PNETs) as well as in non-PNETs and its presence is reported to correlate with tumor prognosis in non-endocrine tumors. However, little data are available from prospective studies on gastrinomas.Experimental design:We assessed occurrence of 3p LOH in 24 gastrinomas and correlated its presence with tumor biological behavior and other clinicopathological features of gastrinomas.Results:Either 3p LOH or microsatellite instability involving 3p occurred in 11 of 24 tumors (46%). Seven (29%) gastrinomas had 3p LOH. Of the 7 gastrinomas with 3p LOH, 5 (71%) had 3p12 LOH with the marker D3S2406, which was the shortest region of highest overlap (SRO). Chromosome 3p LOH was not associated with aggressive biological behavior of gastrinomas or with poor prognosis of patients with gastrinoma. Similarly, 3p12 LOH (SRO) was not correlated with aggressive growth of tumors and/or liver metastases.Conclusion:Gastrinomas have a relative high frequency of 3p12 LOH suggesting this area may harbor putative tumor suppressor gene(s), which may play a role in the tumorigenesis, but not aggressiveness, of a subset of these tumors.