简介：Objective:ToexploretherelationshipbetweenquantitativeTreponemapallidumDNA(TP-DNA)PCRtestingandtheToludineRedUnheatedSerumTest(TRUST)inpatientswithsyphilisbeforeandaftertreatment,andevaluatetheclinicalvalueofquantitativeTP-DNAtestinginthediagnosisandtreatmentevaluationofsyphilis.Methods:29patientswithprimary(12cases)orsecondary(17cases)syphilis,whometthecriteriasetforthisstudywererecruitedassubjects.Allpatientsweretreatedwith2.4millionunitsbenzathinepenicillinIMweeklyfor3weeks.QuantitativetestsofTP-DNAinthepatients'plasmawereperformedusingFQ-PCRbeforeandafterthetreatment.SerologictestsincludingTRUSTandTPPAwerealsoperformed.Results:Beforethetreatment,9outof12primarysyphilispatients(75%)andallsecondarysyphilispatients(17/17)testedpositiveforTreponemapallidum(TP)byTP-DNAtesting.TheaveragequantitativetestvaluesofTP-DNAinprimaryandsecondarysyphilispatientswere(3.38±2.34)×10^4and(5.73±1.33)×10^6copies/ml,respectively.Afterthreemonthsoftreatment,1ofthe9primaryand5outof17secondarysyphilispatientswerepositiveuponTP-DNAtesting,respectively.TheaveragequantitiesofTP-DNAwere2.01×10^2copies/mlinprimaryand5.87×10^2copies/mlinsecondarysyphilispatientswithpositiveTRUSTandTP-DNAtests,and3.09×10^2copies/mlforthosewithnegativeTRUST,respectively.Afterninemonthsoftreatment,alltheprimaryandsecondarysyphilispatientswerenegativeuponTP-DNAtesting,whileallprimaryand14of17(82.35%)secondarysyphilispatientsshowednegativeTRUSTresults.Conclusion:ThattheresultsofTP-DNAtestsarenotconsistentwiththoseofTRUSTbeforeandaftertreatmentindicatesthatquantitativeTP-DNAtestingmayhavevaluableclinicalsignificanceintheearlydiagnosisandevaluationoftreatmentregimensforsyphilis.

简介：Objective:Chemotherapyisthestandardtreatmentforsmall-celllungcancer(SCLC),andleukopeniaisacommonsideeffect.Thisstudyassesseswhetherchemotherapy-inducedleukopeniaisapredictorofefficacyandwhetheritisassociatedwiththesurvivalofSCLCpatients.Methods:Aretrospectiveanalysiswasconductedondatafrom445patientswithSCLCwhoreceivedstandardchemotherapyfor4to10cycles.TheWorldHealthOrganizationgradingsystemclassifiesleukopeniaduringchemotherapyasfollows:absent(grade0),mild(grades1and2),orsevere(grades3and4).Theprimaryendpointisoverallsurvival(OS).Results:Theassociationbetweenchemotherapy-inducedleukopeniaandOSwasassessed.AccordingtoamultivariateCoxmodelwithtime-varyingcovariates,thehazardratioofdeathwassignificantlyloweramongpatientswithmildleukopeniathanamongpatientswithsevereleukopeniaat0.687(0.506to0.943)and1.414(1.147to1.744),respectively.Themediansurvivalwas13months(95%CI:11to15months)forpatientswhodidnotexperienceleukopenia,17months(95%CI:14to18months)forthosewithmildleukopenia,and14months(95%CI:13to16months)forthosewithsevereleukopenia(absentvs.mildvs.severeleukopenia,P=0.047).Conclusion:LeukopeniaduringchemotherapyisassociatedwiththesurvivalofSCLCpatients.Mildleukopeniaisstronglyassociatedwithlongersurvivaltime.

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简介：ＣｕｍｕｌａｔｉｖｅｆｒｅｑｕｅｎｃｙｂｖａｌｕｅｗｉｔｈｏｕｔｕｐｐｅｒｂｏｕｎｄｍａｇｎｉｔｕｄｅａｎｄｉｔｓｒｅｇｒｅｓｓｉｏｎｄｅｔｅｒｍｉｎａｔｉｏｎＪｉａｎ－ＷｅｎＳＨＥＮ（沈建文）（ＳｅｉｓｍｏｌｏｇｉｃａｌＢｕｒｅａｕｏｆＡｎｈｕｉＰ...

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简介：Inthispaper,weestablishaLyapunov-typeinequalityforfractionaldifferentialperiodicboundary-valueproblems.Asapplications,anecessaryconditionisobtainedtoensuretheexistenceanduniquenessofnontrivialsolutionstothisproblem.

简介：Usingthetheoryofcoincidencedegree,aclassofhigherordermulti-pointboundaryvalueproblemforordinarydifferentialequationsarestudied.Undertheboundaryconditionssatisfyingtheresonancecase,somenewexistenceresultsareobtainedbysupposingsomeconditionstothenonlineartermandapplyingaprioriestimates.

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简介：Inthispaperwediscusstheexistenceofatleastthreesolutionsforaclassofgradientmixedboundaryvaluesystems.TheapproachisfullybasedonarecentthreecriticalpointstheoremofB.Ricceri[Athreecriticalpointstheoremrevisited,NonlinearAnal.,70:9(2009),3084-3089].

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简介：一个特征抽取方法在水下回响被建议，它使用SWT(静止小浪变换)的冗余性性质和SVD(单个价值分解)的稳定的性质。后来把SWT系数矩阵的单个值用作特征向量，与到multi-subspace信号的K-L变换从SWT获得了，它实质上是一个特征压缩方法。基于分离直角的小浪变换(DWT)与亚乐队精力的方法相对照展示，湖试用数据的更好的结果与这个方法被获得：(1)在一样的样品和距离在内班下面，距离在班之间比大以前；(2)正确识别率也比前者高，训练并且测试的样品是否从一样的湖小道被选择；(3)取样集合变化，正确识别率的变化范围是远的不到前者。因此，这个方法能获得更柔韧的、有效特征和更好正确的识别结果。

简介：Asystematicstudywasmadeonthetopologicalnatureofthesystemofnon-staticrotatingfluid.Severalinitial(boundary)valueproblemsandtheirwell-posednesswerediscussed.

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简介：在这份报纸，当边界价值取决于时间t时，我们在一种尺寸涉及Landau-Lifshitz方程的知更鸟边界价值问题的全球光滑的答案的存在和唯一。由粘性消失途径，没有抑制边界价值独立于t的术语的吉伯，而且，我们得到这个问题的存在和唯一。

简介：Thispaperpresentsthelowerboundsandupperboundsforthemeanvalueandvarianceofdistancedistributionofnon-linearcodesinGF(q).Bypresentingseveralexamples,itisshownthattheseboundscouldbeachieved.

简介：Thepapercameupwiththebasicprinciples,technologysystem,planningandforestgovernancesystemofclose-to-natureandvalue-orientedforestmanagementonthebasisofdiscussionsonitsconceptandtheoreticalfoundation,andfinallyintroducedinitialeffectsofclose-to-natureandvalue-orientedforestmanagementimplementedinHarbin.

简介：Aclassofboundaryvalueproblemsforathird-orderdifferentialequationwithaturningpointisconsidered.Usingthemethodofmultiplescalesandothers,theuniformlyvalidasymptoticexpansionofsolutionfortheboundaryvalueproblemisconstructed.