简介：Peaceiscloselyrelatedtohumanrightsandtherealizationofhumanrightsisbasedonapeacefulenvironment.Itisbeneficialtothewholeworldtoprotecthumanrights.UnitedNationsHumanRightsCouncildevotesitselftotherelevantdeclarationsofrighttopeace,leadingtoheateddebatesbetweendevelopedanddevelopingcountries.Thispaperholdsthattherighttopeacerootsinseekingofhumandignity,anditisbothindividualandcollectivehumanrights.Therighttopeaceenumeratestherangeofindividualsandpeople,anditstressesthestateresponsibilityinparticular.Thecontentoftherighttopeaceoverlapsthecurrentinternationalsystemofhumanrights.Thecoreoftherighttopeaceisnon-derogablerights.Weshouldprotectitviabothinternationalhumanrightslawandinternationalhumanitarianlawduringtheperiodofwarandarmedconflict.

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简介：TheFourthBeijingForumonhumanRightswasheldinBeijingfromSeptember21-23,2011.JointlysponsoredbytheChinaSocietyforhumanRightsStudiesandtheChinahumanRightsDevelopmentFoundation,theforumwascenteredonthethemeof'CulturalTradition

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简介：Internationalhumanrightsinstruments,includingtheUniversalDeclarationofHumanRights(UDHR),theInternationalCovenant

简介：China’saccessiontotheWorldTradeOrganization(WTO)representsastrategicsteptakenbythecountrytoopenitselfevenwidertotheoutsideworld,indicatingitsreadinesstogetinvolvedintheprocessofeconomicglobalization.

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简介：ＤＩＥＬＥＣＴＲＩＣＰＲＯＰＥＲＴＩＥＳＯＦＨＵＭＡＮＢＲＥＡＳＴＣＡＲＣＩＮＯＭＡＡＮＤＳＵＲＲＯＵＮＤＩＮＧＴＩＳＳＵＥＳＤＩＥＬＥＣＴＲＩＣＰＲＯＰＥＲＴＩＥＳＯＦＨＵＭＡＮＢＲＥＡＳＴＣＡＲＣＩＮＯＭＡＡＮＤＳＵＲＲＯＵＮＤＩＮＧＴＩＳＳＵＥ...

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简介：AdozenhumanrightsexpertsandscholarsfrominstitutionsofhigherlearningandresearchorganizationsattendedaforumhembytheChinaSocietyforHumanRightsStudies(CSHRS)inBeijinginearlyMarch.Withalargeamountoffacts,theyrefutedthe2001countryreportsonhumanrightsissuedonMarch4bytheUSDepartmentofStateforitsviciousdistortionandattacksonChina’shumanrights.Followingareexcerptsoftheirspeeches.

简介：Peacecanbeunderstoodasapactfortheperfectionofinstitutionsandthroughthemthepositivationofrights.Intoday’sworld,internationalwarsandconflictsaremarkedbytheculturalidentitiestowhichtheyrelate,bringingtotheforehistoricalsocialandhumanitarianinjustices.Inthissense,itispossibletorethinkpeacestudiesviathecommunitarianperspective.Suchaperspectivepointstosocialrecognitionfortheappealtohumandiversity,valuesbeingconstructedaccordingtoeachsocietyorsocialgroupandnotaprioriwithliberalpresuppositions.Inasocietywhererightsexistforonegroupandnotforanother,theidentityoftheunrecognizedgroupoccursthroughdenialofrights.Inadditiontodiscrimination,non-realizationofrightsequallyforallcauseslow-esteemandinhumanityobscuringsocialinteractionthathindersrecognition.Inthiscontext,thisarticledefendswhatisexpectedasminorityrecognitionisthepossibilityofself-affirmationasagroupthroughtherealparticipationofminoritymembersinthemajoritygroupofequitableformsfortheestablishmentofparticipatorygovernanceofcivilsocietyintheeffectivenessofpeace.

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简介：Objective:ToinvestigatetheexpressionofHPV16mRNAinnormalhumankeratinocytestransfectedwithpSV2-neo/16.Firsthumankeratinocyteswereculturedintheserum-freemediumM154.Second,theplasmidpSV2-neo/16wastransfectedintothehumankeratinocytesusingatransfectingreagent.Third,RT-PCRandSouthernBlottingwereusedtodetecttheexpressionofHPV16mRNAandDNAinthetransfectedkeratinocytes,respectively.Results:TheexpressionofHPV16mRNAwassuccessfullyamplifiedandan110bpwasditectedbyRT-PCR.A7.9kbfragmentwasconfirmedinthetransfectedkeratinocytesbySouthernBlotanalysis.Conclusion:HPV16mRNAandDNAweresuccessfullydetectedinthehumankeratinocytes.

简介：Interleukin(IL)-15在生来的杀手(NK)和CD8+T房间增长和功能起一个重要作用并且是比为肿瘤免疫疗法的IL-2更有效的。由附近的房间的IL-15的trans演讲比它的可溶的IL-15为NK房间激活是更有效的。在这研究，熔化蛋白质dsNKG2D-IL-15，由经由一个连接器联合到人的IL-15的人的NKG2D的二相同的细胞外的域组成了，在Escherichiacoli被设计。DsNKG2D-IL-15能高效地与二个NKG2D领域和trans礼品IL-15把人的肿瘤房间的链相关的蛋白质A(云母)绑在主要histocompatibility建筑群一级到NK或CD8+T房间。我们移植了人的胃的癌症(SGC-7901)房间进裸体老鼠和有进C57BL/6老鼠的云母(B16BL6云母)的宫外的表示的老鼠黑瘤房间。然后，我们学习了反肿瘤效果在二个xenografted肿瘤模特儿由dsNKG2D-IL-15调停了。人的dsNKG2D-IL-15在压制胃的癌症生长比IL-15展出了更高的效率。外长的人的dsNKG2D-IL-15集中地在老鼠肿瘤纸巾被散布基于在vivo实时成像。房间渗入了进跟随外部血mononuclear房间的注射进忍受人的胃的癌症的裸体老鼠的肿瘤纸巾的人的CD56+的频率被人的dsNKG2D-IL-15治疗显著地增加。人的dsNKG2D-IL-15也由激活和招募的老鼠NK和CD8+T房间推迟了移植黑瘤(B16BL6云母)的生长。在C57BL/6老鼠的人的dsNKG2D-IL-15的反黑瘤效果主要被减少由在里面老鼠NK房间的vivo弄空。这些数据热点为肿瘤的人的dsNKG2D-IL-15的潜在的使用治疗。

简介：AbstractBackground:Compared to adult studies, studies which involve the treatment of pediatric congenital hypogonadotropic hypogonadism (CHH) are limited and no universal treatment regimen is available. The aim of this study was to evaluate the feasibility of human chorionic gonadotropin (hCG)/human menopausal gonadotropin (hMG) therapy for treating male adolescents with CHH.Methods:Male adolescent CHH patients were treated with hCG/hMG (n = 20) or a gonadotropin-releasing hormone (GnRH) pump (n = 21). The treatment was divided into a study phase (0-3 months) and a follow-up phase (3-12 months). The testicular volume (TV), penile length (PL), penis diameter (PD), and sex hormone levels were compared between the two groups. The TV and other indicators between the groups were analyzed using a t-test (equal variance) or a rank sum test (unequal variance).Results:Before treatment, there was no statistical difference between the two groups in terms of the biochemistry, hormones, and other demographic indicators. After 3 months of treatment, the TV of the hCG/hMG and GnRH groups increased to 5.1 ± 2.3 mL and 4.1 ± 1.8 mL, respectively; however, the difference was not statistically significant (P > 0.05, t= 1.394). The PL reached 6.9 ± 1.8 cm and 5.1 ± 1 .6 cm (P < 0.05, t= 3.083), the PD reached 2.4 ± 0.5 cm and 2.0 ± 0.6 cm (P < 0.05, t= 2.224), respectively, in the two groups. At the end of 6 months of treatment, biomarkers were in normal range in the two groups. Compared with the GnRH group, the testosterone (T) level and growth of PL and PD were significantly greater in the hCG/hMG group (all P < 0.05). While the TV of both groups increased, the difference was not statistically significant (P > 0.05, t = 0.314). After 9 to 12 months of treatment, the T level was higher in the hCG/hMG group. Other parameters did not exhibit a statistical difference.Conclusions:The hCG/hMG regimen is feasible and effective for treating male adolescents with CHH. The initial 3 months of treatment may be a window to optimally observe the strongest effects of therapy. Furthermore, results from the extended time-period showed positive outcomes at the 1-year mark; however, the long-term effectiveness, strengths, and weaknesses of the hCG/hMG regimen require further research.Trial Registration:ClinicalTrials.gov, NCT02880280; https://clinicaltrials.gov/ct2/show/NCT02880280.

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简介：Thelogicofatheoreticalsystemistheinnerlogicalrelationshipofthetheoreticalsystem.Sincethe17thNationalCongressoftheCommunistPartyofChina,therehavebeenabundantresearchachievementsregardingthetheoryofsocialismwithChinesecharacteristics,whiletherehasbeenalackofsystematicresearchanddiscussionofthesocialisthumanrightstheorywithChinesecharacteristics.Therefore,researchonthesocialisthumanrights

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简介：AbstractAntimicrobial peptides (AMPs) are the natural antibiotics recognized for their broad-spectrum resistance to bacteria, fungi, viruses and parasites, and influencing the host immune responses. AMPs attributed to good biological effects have been used in various areas of human health, which are trying to completely replace antibiotics, owing to serious drug-resistance bacteria. However, limited bioactivity and potential biotoxicity of some AMPs was neglected, attributable to their hydrophobic structure with positive charges and nonspecific destruction of cell membranes. Various strategies have been used to design and biosynthetic optimized AMPs to improve their bioactivity, productivity, while lowering host toxicity and cost. Here, we focus on the progress made in understanding the AMPs, including biosynthesis (AMP-BioDesign 1.0 and 2.0), bioactivity (e.g. immune regulation and broad-spectrum or nonspecific actions against bacteria, viruses or parasites), and principle biotoxicity (e.g. hemolysis, acute toxicity and instability, ect). The application prospects of AMP for human health, clinical medicine (for novel drugs), tissue engineering and drug delivery system, respectively, are summarized in this review. Furthermore, future prospects and new strategy for the development of effective and low-toxic AMP formulations for human health are discussed.