简介:瞄准:在二个不同耐心的位置调查在食道的测压法和pH加速方法之间的协议。方法:十八个题目在学习被包括。首先,到更低的食道的括约肌(LES)的近似边阶的从鼻子的距离被测量压力计的联盟者。然后一个不同调查者,被使看不见第一研究的结果,用pH加速方法测量了一样的距离,与病人在一起正直并且背卧位。对在二种技术之间的同意的一个评价被执行。结果:在背卧位,仅仅一个题目的测量在为正确的放接受的范围(对LES3厘米远侧或近似的<=)外面。在正直的位置,在测量的错误在五个题目被认出。Bland-Altman阴谋表明在大小之间的好同意获得了压力计的联盟者并且由在与在背卧位的病人一起的方法上面的pH步。结论:在情况中非压力计的察觉设备的可获得性,pH加速方法能便于放在背卧位与病人一起监视导管的24hpH。如果我们的结果被进一步的研究支持,这应该与怀疑的胃的食道的倒流疾病为题目在临床的实践增加pH-metry的使用。
简介:Threekeyfactorsarediscussed,whichaffectpositioningaccuracyofrange-rangepositioningmodeandhyperbolicpositioningmode.Basedontheerrorellipticaltheory,theexpressionsofpositioningerrorandofpositioninggeometricfactorofrange-rangepositioningmodeandhyperbolicpositioningmodearederived,andthepositioningerrorandtheblindpositioningareaoftwodifferentpositioningmodesareanalyzed.Accordingtotherequirementofnavigationarea,anoptimumpositional
简介:Inthe20yearsaftertheUNEnvironmentandDevelopmentConferencein1992,theessentialissuesinrelationtosustainabledevelopmenthavebeenunsolved.Theupcoming"Rio+20"conferenceputthefocusontheshifttowardsgreendevelopment.Toachievethisrequiresthechangeofsomeideologiesthatdominatehumanactions,suchastheconceptsofwealth,welfareandsecurity,anditalsorequireidentifyingthenewpositionofnatureresources,especiallythepositionofforest.Itwaspointedoutinthepaperthatforestisthefoundationofsocioeconomicdevelopmentandconstitutesbasicwealth,basicwelfareandbasicsecurityofthewholecommunityunderthegreendevelopmentcontext.Nevertheless,itisamusttoaggressivelyinvestanddevelopgreeneconomy.Itwasalsoproposedtosetupforestrydevelopmentorganizations,investmentmechanisms,policysystemandresearch&educationsystemcompatiblewithgreendevelopment.Moreover,someforestrypoliciesthatshouldberevisedwerecombed.
简介:PATIENTMONITORINGSYSTEMPATIENTMONITORINGSYSTEMHauGuifen;LiuGuangrong(ChinesePLA.GeneralHospital100853,Beijing,China)SuchasPat...
简介:我们在原生生物Trichomonasvaginalis的最近的调查与120.9nt的单位长度建议了DNA顺序频率,它为放的nucleosome代表顺序签名。我们现在在更高的优核质扩大了我们的观察并且在Caenorhabditiselegans在长度识别了175nt的类似的频率。在定义顺序的过程组合特征,我们发现10.5-nt频率,DNA双螺旋的顺序签名,不能为放的cross-nucleosome足够,但是提供指导栏杆便于的必需品放。我们推进把的保护nucleosome的序列并且从第5'-e识别了一个强壮的积极嘌呤(AG)坡度到第3'-e,并且当嘌呤内容断然与GC内容被相关,也听说充实nucleosome的区域作为与nucleosome免费的序列相比GC富有。顺序描述允许我们开发一个隐藏的Markov模型(唔)为译码nucleosome放的算法计算地,并且基于从C的第五个染色体的一套训练数据。elegans,我们的算法比随机的放预言了放得好的nucleosomes的60%-70%,它高是15%-20%。我们断定nucleosomes随机没在DNA序列上被放并且还与可变稳定性,DNA上的放得好的nucleosomes叶子顺序签名,并且到对面的nucleosomes的统计的放绑在不同染色体区域染色体能基于这些顺序签名计算地被译码。
简介:Clinicaldecision-makingiswhatallcardiovascularphysiciansdo.Thepurposeofdecision-makingistomakethediagnosis,decideonappropriatetherapyandestimatetheprognosisoftheindividualpatient.Regardingtheprognosis,populationprognosticdataisusedbutthismayormaynotapplytotheindividualpatient.LVfunction,nomatterhowitisdeterminedseemstocorrelatebestwithprognosis.Butweneedtorememberthatprognosticationoftheindividualis,atbest,aneducatedguess.
简介:Objective:Toevaluatetheauditoryfunctionofanindividualwithgeneticallyconfirmedhemochromatosis.Methods:A57yearoldmalewithmildlyimpairedsounddetectionthresholdsunderwentarangeofbehavioural,electroacousticandelectrophysiologicassessments.Theseincludedtherecordingofotoacousticemissionsandauditorybrainstemresponses,measurementofmonauraltemporalresolutionandevaluationofbinauralspeechprocessing.Findingsforthispatientweresubsequentlycomparedwiththoseof80healthycontrolswithsimilaraudiometricthresholds.Results:Thepatientshowedthethreecardinalfeaturesofauditoryneuropathy,presentingwithevidenceofnormalcochlearouterhaircellfunction,disruptedneuralactivityintheauditorynerve/brainstemandimpairedtemporalprocessing.Hisfunctionalhearingability(speechperception)wassignificantlyaffectedandsuggestedareducedcapacitytouselocalizationcuestosegregatesignalsinthepresenceofbackgroundnoise.Conclusion:Wepresentthefirstcaseofanindividualwithhemochromatosisandauditoryneuropathy.Thefindingsforthispatienthighlighttheneedforcarefulevaluationofauditoryfunctioninindividualswiththedisorder.
简介:Beampositioningstabilityinalaser-driveninertialconfinementfusion(ICF)facilityisavitalproblemthatneedstobefixed.Eachlaserbeaminthefacilityistransmittedinlotsofopticsforhundredsofmeters,andthentargetedinamicro-sizedpellettorealizecontrollablefusion.Anyturbulenceintheenvironmentinsuchlong-distancepropagationwouldaffectthedisplacementofopticsandfurtherresultinbeamfocusingandpositioningerrors.Thisstudyconcludedthattheerrorsoneachoftheopticscontributedtothetarget,anditpresentsanefficientmethodofenhancingthebeamstabilitybyeliminatingerrorsonerror-sensitiveoptics.Optimizationsoftheopticalsystemandmechanicalsupportingstructuresarealsopresented.
简介:Theidealmodelofhumanrightslawstudiesshallbeonethatisopenandcomprehensive.Onthebasisofnormativelegalstudies,itshallpaymoreattentiontoandrespondtopolitical,economic,andsocialdevelopmentinawiderangeofhumanrightsissues.Thesestudiesshouldattempttofindpracticalsolutionstoconcreteproblems.Humanrightslawshouldbearelativelyindependentlegaldiscipline,anditshouldbeaproblem-orientedobjectofstudy.Regardingtheresearchmethodologies,humanrightslawcouldencompassallaspectsoflegalstudies,andgobeyondlegalthemtosomeextenttoencompasstheinfluenceofotherdisciplines.
简介:Inprimarymitralregurgitationthereareanatomicabnormalitiesofthemitralvalvecausingbackwardflow,placingahemodynamicburdenontheleftventricle.Ifthisburdenissevereandprolonged,itleadstoleftventriculardamage,heartfailure,anddeath.Thepreferredtherapyisrestorationofmitralcompetencethroughmitralvalverepair,whichissaferthanmitralvalvereplacement.Whenrepairisperformedinatimelyfashion,lifespancanbereturnedtothatofanormalindividual.Triggersfortimelyrepairincludetheonsetofsymptomsandevidenceofleftventriculardysfunctionasdeterminedbyejectionfractionfallingtoward60%and/orend-systolicdimensionincreasingtoward40mm.
简介:瞄准:有希望地在年轻病人学习发生和尖锐憩室炎的自然科学。方法:与尖锐憩室炎的诊断在我们在2000年1月之间的医院就医到2005年2月的207个病人的一个总数被包括。他们的人口统计的特征,病历,physical,X光线照相术、内视镜的调查结果以及治疗被记录。病人们被跟随为第一年的每6瞬间并且以后每年。结果:吝啬的病人的年龄是61(范围27-92)年。25个病人(12%)比45年年轻。尖锐憩室炎是显著地,在在年轻年龄组的男性之中流行的更多作为与老年相比组织(19/25,76%对61/182,33%,分别地P=0.0001)。复杂并发症更经常发生在年轻年龄组;32%对13%,(P=0.002)。在后续期间,6个病人(28%)在老年组作为与87个病人(55%)相比在年轻年龄组仍然保持无征状(P=0.024)。作为结果,sigmoidectomies是被执行两次经常在年轻年龄组(38%对13%,P=0.002)。结论:在年轻病人的憩室炎有男优势,有复杂并发症和更高的再发率的更高的率的一堂更好攻击的功课。一条更早外科的途径可能与尖锐憩室炎在年轻病人被考虑。
简介:Aseriesofadvantagesofsingledifference(SD)andundifferenced(ZD)modelsaregivenascomparedwitythedoubledifferenceezistinSDandZDmodels.Thereparameterizationmethodisprovidedtoresolvethisrankdefectproblembyestimatingsomecombinationsoftheunknownsratherthantheunknownsthemselves.TherepatameterizationofSDandZDfunctionalmodelsisdiscussedindetailwiththeirstochasticmodels.Thetheoreticalcomformationoftheequivalenceofundifferencedanddifferencedmodelsisdescribedinastraightforwardway.TherelationshipbetweenSDandZDresidualsisgivenandverifiedforsomespecialpurposes,e.g.researchonthestochasticalpropertiesofGPSobservations.