简介:Theinteractionsofoxidativeradicals(Br2,HOetc.)withN-phosphoryldipeptidederivatives(NDM-TrpOMeandNDT-MetOMe)havebeeninvestigatedbyusingpulseradiolysisatdifferentpHvalues.IthasbeenfoundthatBr2andHOradicalsoxidizetheMet-siteandTrp-siteinthedipeptidederivativesviaformationofthethree-electron-bondedintermediateandindolylradicalsimultaneously.Thentheintramolecularelectrontransferalongthepeptidebackboneoccurs.Therateconstantsofelectrontransfer,k,havebeendeterminedandthereactionmechanismhasbeendeduced.
简介:想必校园MM们都有被男生追的经历吧!如果他是你的梦中情人倒也罢,可如果不是,那么如何拒绝就是考验你的时刻了,该怎么说?怎么做?是否有效?如果你正被这个问题困扰,那么就来听听大家的说法吧!
简介:Theemploymentofboth"bipartite"and"tripartite"nominalsentencepatternscontainingdemonstrativesofthen-seriesinMiddleEgyptian~1showsacharacteristicsufficientlyconsistenttowarrantthesuggestionthatasemanticconstraintisoperative:VIZ.,thatthosesentencesareemployedwithNPsthatare[-PERSON],not[+PERSON].Therefore,sentencessuchas~*R’/it.i/ink(pw)nn/nf(3)/n3/nwareexcluded.Inasentencesuc(?)asbit.ipwn3"Thisismycharacter/conduct"~2,bit.i"mycharacter/conduct"is[-PERSON],whereasonecouldnotsay,e.g.,~*s3.ipwn3"Thisismyson."Accordingtothishypothesis,allMiddleEgyptian
简介:Difluorocarbenegeneratedfromthedecompositionoffluorosulfonyldifluoroaceticacid(2)reactedwithvarioussodiumsaltsofN-heterocycliccompounds(1)givingthecorrespondingdifluoro-methylatedproductsinacetonitrileat10—40℃.Benzotriazole(1a),benzimidazole(1b)andimidazole(1c)wereconvertedinto1-(difluoromethyl)benzotriazole(3a),1-(difluoromethyl)benzimidazole(3b)and1-(difluoromethyl)imidazole(3c)respectively.Indole(1d)reactedwith2togive-(fluorosulfonyldifluoro-acetate)indole(2d)ratherthantheexpecteddifluoromethylatedderivatives.