简介:Itisprovedthatthereisnochaoticgroupactionsonanytopologicalspacewithfreearc.InthispaperthechaoticactionsofthegrouplikeG×F,whereFisafinitegroup,arestudied.Inparticular,underasuitableassumption,ifFisacyclicgroup,thenthetopologicalspacewhichadmitsachaoticactionofZ×Fmustadmitachatotichomeomorphism.Atopologicalspacewhichadmitsachaoticgroupactionbutadmitsnochaotichorneomorphismisconstructed.
简介:AbstractBackground:Resting heart rate (RHR) is considered as a strong predictor of total mortality and hospitalization due to heart failure in hypertension patients. Bisoprolol fumarate, a second-generation beta-adrenoreceptor blockers (β-blocker) is commonly prescribed drug to manage hypertension. The present study was to retrospectively evaluate changes in the average RHR and its association with cardiovascular outcomes in bisoprolol-treated coronary artery disease (CAD) patients from the CAD treated with bisoprolol (BISO-CAD) study who had comorbid hypertension.Methods:We performed ad-hoc analysis for hypertension sub-group of the BISO-CAD study (n = 866), which was a phase IV, multination, multi-center, single-arm, observational study carried out from October 2011 to July 2015 across China, South Korea, and Vietnam. Multivariate regression analysis was used to identify factors associated with incidence of composite cardiac clinical outcome (CCCO), the results were presented as adjusted odds ratio (OR) along with 95% confidence interval (CI) and adjusted P value.Results:A total of 681 patients (mean age: 64.77 ± 10.33 years) with hypertension from BISO-CAD study were included in the analysis. Bisoprolol improved CCCOs in CAD patients with comorbid hypertension, with RHR <65 and <70 beats/min compared with RHR ≥65 and ≥75 beats/min, respectively, in the efficacy analysis (EA) set. In addition, it lowered RHR in both intent-to-treat (ITT) and EA groups after 6, 12, and 18 months of treatment. Further, RHR 70 to 74 beats/min resulted in significantly higher risk of CCCOs EA set of patients (adjusted OR: 4.34; 95% CI: 1.19-15.89; P = 0.03). Also, events of hospitalization due to acute coronary syndrome were higher when RHR 69 to 74 beats/min compared to RHR <69 beats/min in ITT patients.Conclusion:Bisoprolol can effectively reduce RHR in Asian CAD patients with comorbid hypertension and hence, improve CCCO without affecting their blood pressure.
简介:OnJune29,2006,theStandingCommitteeoftheNationalPeople'sCongress,theChineseparliament,approvedtherevisedCompulsoryEducationLawofthePeople'sRepublicofChina,whichbecameeffectiveforimplementationonSeptember1.Beforetherevision,thelawhad18articleswithatotalof1,800characters,whichwerenotdividedintochapters.Incomparison,therevisedlawhas63articlesineightchapters,withatotalof7,000characters.'Thankstothis,thefirstmajorrevisionmadetothelawsinceitspromulgationin1986,thelawhasbeenexpandedbothinvolumeandcontent,'ChenXiaoya,vice-ministerofeducation,toldtheHumanRightsmagazine.'Moreover,
简介:知道的人天生的钟工作允许理解什么时候并且治疗为什么是有效的。守夜chronotypes决心和尊重允许避免学者失败。表演取决于chronotypes和时间变化。夜里睡觉周期的最小、最大的持续时间源于在内长、外长的钟之间的相互作用。我们的ecoexotope被是为endophysiotope钟的synchronisers的太阳、月亮、陆上的节奏组织。人夜里睡觉变化取决于月亮的周期乘火车。睡觉分析指向作为控制过去常证实大约每月月亮的大约年度的太阳的节奏。为了证实生理的回答,单个纵的记录被使用。到证据lithotherapeutic效果,刺激回答根据一个双窗帘被测试控制安慰剂的调查。什么矿物质到选择?,为什么?,怎么对待?,什么时候?与控制相比,硬玉的一种或软玉与醒来和泌尿的15褶层减少提高夜里睡觉质量。最高的安慰剂效果在4褶层增加下面。取决于矿物质和踪迹元素,性质变化。矿物质水晶结构被证实有一个行动。有皮肤的接触区域是一个限制因素。安慰剂效果在日子阶段期间是更大的。红碧石处理提高日报的物理工作的数字和紧张。矿物质以一种剂量依赖者方式并且在协同作用行动。赤铁矿脚底给安慰剂效果,但是由15褶层价值增加serpentinite的效果。在一个钟网络以内,全部的潜伏阶段比每只钟的最短的潜伏阶段短,提高系统反应。
简介:<正>InOctober2003,attheWangfujingBookstore,BeijingerswillbeinvitedtoaspeciallauncheventwheretheycanpickupafreecopyofEnglishTaxi,aninnovativenewcomputergamedevelopedbytheBritishCouncil.SponsoredbyZhonghuatoothpaste,EnglishTaxiisthelatest,creativewaytopracticeeverydayEnglishandhasbeendevelopedespeciallyfortheChinesemarket.EnglishTaxihasbeenproducedaspartofThinkUK,whichisbringingthebestofBritishoriginality,creativityand