简介：AbstractPreeclampsia (PE), a multisystem disorder in pregnancy, is a main cause of perinatal mortality and is associated with long-term maternal complications. For a long time, PE was defined as the new onset hypertension and proteinuria after 20 weeks’ gestation. It had been shown that this "gold standard definition" is not able to provide a sufficient prediction of PE-related fetal and/or maternal complications. In 2018 the International Society for the Study of Hypertension in Pregnancy recommended a broader definition of the disease. The new definition of the International Society for the Study of Hypertension in Pregnancy ruled out proteinuria as mandatory for the diagnosis of PE. This new definition increases the number of patients diagnosed as preeclamptic by nearly 21%, which is not accompanied by an increased severity of maternal outcomes. Including angiogenic biomarkers, however, has been shown to increase detection of adverse outcomes.The pathophysiology of PE is complex and not yet completely explained. Advances in prediction and diagnosis have been achieved by discovery and clinical evaluation of biomarkers, especially of placental origin. A broad spectrum of biomarkers has been tested, a few of them have been introduced into the clinical practice as of today. Especially angiogenic biomarkers that are rooted in the pathophysiology of PE have been demonstrated to be important in the prediction and diagnosis of adverse outcomes. At a cut-off value of the soluble fms-like tyrosine kinase-1 (sFlt-1)/placental growth factor (PlGF)-ratio of 85, early-onset PE <34+0 weeks of gestation can accurately be diagnosed with a sensitivity of 89% and a specificity of 97%. The Prediction of short-term outcome in pregnant women with suspected preeclampsia (PROGNOSIS) study has shown that the high negative predictive value (99.3%) of the sFlt-1/PlGF-ratio below 38 in patients with suspected PE rules out the onset of the disease within one week. PROGNOSIS Asia, evaluating the sFlt-1/PlGF-ratio cut-off of 38 in an Asian population, confirmed the excellent accuracy in prediction.Recently, the angiogenic biomarkers have been integrated in multi-marker prediction models. Digital approaches, integrating algorithm-based decision support tools paired with home monitoring devices may be the next step in enhancing predictive accuracy and thus bear the potential to reduce maternal and/or fetal morbidity and mortality and save costs for the payer in parallel. The objective of this review is to provide an overview of current methods for predicting and diagnosing PE.

简介：Basedonhreedifferentimplementationschemes,thispaperstronglydemonstratesthattheperformanceoftheHoughtransformdependscruciallyonitsimplementationscemewhenitisusedforlinedetection.Moreover,theobtainedresultscanbeusedasatheoreticalbasistopredicttheperformanceoftheHoughtransformaswellastoeliminatethenoiseinHoughspacecomingfromimagenoise.

简介：本文给出了完全二部图的P5-因子分解存在的必要条件，同时讨论了充分条件的几种情况，给出了四个猜想。

简介：如果图G有一个生成子图使得这个生成子图的每一个分支都是3个点的路，则称G有P3-因子．本文证明了对任何一个2-边连通图G，只要G的边数能被3整除，则G的线图就有P3-因子。

简介：法藏敦煌P.3861号文献中的梵汉对音资料所呈现的语音规律与《千字文》、《开蒙要训》等敦煌遗存资料大体一致，反映了八、九世纪吐蕃占领敦煌时期河西方音的特点，如清浊界限禾甚分明，鼻音声母m、n、η有向mb、nd、ηg演化的迹象，舌上、齿头、正齿三组字混用，宕、梗、通摄-η尾消变，宕摄元音高化，-m、-n尾也有消变的痕迹，等等。与12世纪的西夏梵汉对音资料相比照，可以知道西夏与敦煌河西方音有明显的承续关系。

简介：摘要目的观察北京0号治疗原发性轻中度高血压的疗效与患者依从性。方法本社区门诊就诊的轻中度高血压患者164例，患者中轻度高血压80例，中度高血压84例，予以北京0号降压治疗1年，观察临床治疗效果及服药依从性。结果显效70例，有效84例，无效11例（其中3例为服药后出现不良反应停服），总效率93%。结论北京0号治疗轻中度高血压疗效确切，价廉物美，患者依从性良好。

简介：2012底至2013年初,郑州市文物考古研究院对郑州市黄河路109号院内两幢住宅楼工程区遗址进行了发掘,清理了殷墟时期小型墓葬43座。随葬品多为陶器,少量铜器、玉器及贝币。按陶器特征分析可将这批墓葬分为两个阶段,分别属于殷墟二期和三期。此次发掘为郑州地区殷墟时期墓葬研究提供了新的实物资料。

简介：摘要：在实施房屋建设项目时，多种风险和不确定因素层出不穷，如果管理不佳，可能导致项目推迟、超越预算，引发一系列负面影响。本文以识别和应对房建项目中的风险为中心，进行深入探讨。全方位识别房建项目的各项风险，包括设计、施工、合同、环境等各个环节的风险，并适当设置风险识别指标体系。通过结合定性和定量的分析手段，对众多风险因素进行影响度评估，为风险应对提供数值参考。根据风险识别和影响评估的结果，提供了一整套风险应对措施，涉及到优化设计、规范施工、强化合同管理以及环境保护等方面，意在减少风险对房屋建设项目带来的潜在损失。通过案例分析验证了风险管理策略的实际效果。研究结果对于指导房建项目的风险管理具有重要参考价值。

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简介：本文介绍不同图书馆在人物传记类图书的分类排架号的给法上的不同之处,阐述了这一特定类图书的分类排架技巧.

简介：10月12日，作为文化艺术品代表的《长征万里图》搭乘在神舟六号上飞入太空，五天后安全返回。

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简介：任何问题的解决，是从形成该问题某种复杂系统的主要分量（因素）分类开始的；调查的下个阶段，对基于某些标志、等级和评价的各种因素的分类进行研究。

简介：目前,油气储量6P分类在石油公司中已逐渐流行.要正确理解油气储量6P分类及其相关概念,需要注意3个关键问题:(1)6P分类的对象;(2)如何正确理解油气商业性概念?(3)如何认识地质把握程度?文中对上述关键问题提出了看法,并阐述了在准确理解和应用6P分类中应注意的问题.

简介：南宁工务段对管内大型编组场的P43—6号对称道岔磨耗过快的成因进行了分析，采取加强道岔强度、整正道岔位置、加长护轮轨及清筛道床和换砟等措施进行整治，降低了磨耗，提高了道岔设备质量，达到延长设备服役寿命和降低维修养护成本的目的。

简介：1．引言P2P对等网络是非中心化网络，信息的交换不需要通过创建的中心站点，而直接在对等设备（如个人计算机）间动态地进行信息交换和服务，是一种高效直接的传输方式。P2P打破了传统的C／S模式，各节点对等并可互相提供服务。P2P对等应用在互联网中已经非常普及，并且成为网络资源的巨大消耗者。随着移动数据业务与可承载数据业务终端的普及，以及移动通信网络的快速发展，移动终端与网络结合得越来越紧密，在移动环境中如何实现P2P应用已经引起广泛关注。

简介：校园网作为学校教育与信息交流的基础设施，有着不可替代的重要作用。现今，网络应用（如P2P、流媒体、即时通信）不断增加，异常流量（如蠕虫、DOS攻击）也不断涌现，使校园网核心设备难以招聚面对校园网流量产生的巨大压力，网络带宽一扩再扩，但仍不能满足需求。网络带宽费用不断增加，可网络拥塞问题并未改善

简介：Thegoverningequationsofsurface-deformationinfully-penetratedGTAWweldpoolarederived.ThesolutionschemeoftheLagrangemultiplier,whichmakesthetopsurface-deformationequationbecoupledwiththatforthebottom-surfaceofasingleweldpool,isgivenout.Throughnumericalanalysisofweldpoolsurface-deformationinGTAW,itisfoundthatthereisclearcorrelationbetweenthepenetrationextentandtheLagrangemultiplier,inadditiontotherelationshipbetweenthepenetrationextentandthemaximumdepressionandhumpaswellasthedepressedvolumeofthetopsurfaceofweldpool.Itlaysgoodfoundationfortop-sidesensingbasedweldpenetrationcontrol.

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简介：Inthispaper,thej,υcorrectedformulaeoftheamplitudesandthephasesof58astronomicalconstituentsaregiven,andthemodelsfortheanalysisandpredictionof169constituentsarepresented.ThenewCartwright’scalculatedresultsofthetidalpotentialareused,andthequadraticanalysisismade.Ithasbeenprovedbyanumberoftrialsthattheharmonicconstantsofconstituentsaremorestableandtheaccuracyofthepredictedresultreliable.