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179 个结果
  • 简介:Asingle-particlemicrobeamfacilityhasbeenconstructedattheLaboratoryofIonBeamBioengineering(LIBB),ChineseAcademyofSciences.Thesystemisdesignedtodeliverthedefinednumberofhydrogenions,coveringarangeofenergyfrom1.0to3.5MeV,intoanareasmallerthanthenucleiofindividuallivingcells.AccuracyoftheparticledetectionsystemandthecelltargetingsysteminthefacilityhasbeenassessedusingCR39(nucleartrackdetector)for2.3MeVprotons.Theresultsdemonstratethattheparticledetectionefficiencyisabove98%,andtheoveralltargetingaccuracyofthemicrobeamislimitedwithin3μmformorethan90%hits.

  • 标签: 单粒子微光束设备 精确性测量 生物工程离子束实验室 单细胞照射 原子核轨迹探测
  • 简介:Recently,RNAprocessinghasemergedasanovelpathwaythatmaycontributetothemaintenanceofgenomestability[1].Alternativesplicingisakeymolecularmechanismforincreasingthefunctionaldiversityoftheeukaryoticproteomes,butitalsooftenalteredincancer.Mountingevidenceindicatesthatalternativesplicing,theprocessthatallowsproductionofmultiplemRNAvariantsfromeachgene,contributestotheheterogeneityofthedisease[2].Althoughthemechanismofalternativesplicingvariantincancerisunclear,thecancer-specificalternativesplicingvariantshavebeenobservedinavarietyofhumancancersandcancercelllinesandhavebeenconnectedtotumorgenesis.

  • 标签: CARBON ION IRRADIATION
  • 简介:Thispaperdealswithamethodologyforsinglegatelocationoptimizationforplasticinjectionmold.Theobjectiveofthegateoptimizationistominimizethewarpageofinjectionmoldedparts,becausewarpageisacrucialqualityissueformostinjectionmoldedpartswhileitisinfluencedgreatlybythegatelocation.Featurewarpageisdefinedastheratioofmaximumdisplacementonthefeaturesurfacetotheprojectedlengthofthefeaturesurfacetodescribepartwarpage.Theoptimizationiscombinedwiththenumericalsimulationtechnologytofindtheoptimalgatelocation,inwhichthesimulatedannealingalgorithmisusedtosearchfortheoptimum.Finally,anexampleisdiscussedinthepaperanditcanbeconcludedthattheproposedmethodiseffective.

  • 标签: 注射模拟 最优化 塑料材料 成型加工
  • 简介:TheangledependenceofopticalphononmodesofanAlNbulksinglecrystalfromthem-plane(1100)andc-plane(0001)surfaces,respectively,isinvestigatedbypolarizedRamanspectroscopyinabackscatteringconfigurationatroomtemperature.CorrespondingRamanselectionrulesarederivedaccordingtomeasuredscatteringgeometriestoillustratetheangledependence.Theangle-dependentintensitiesofphononmodesarediscussedandcomparedtotheoreticalscatteringintensities,yieldingtheRamantensorelementsofA1(TO),E22,E1(TO),andA1(LO)phononmodesandtherelativephasedifferencebetweenthetwocomplexelementsofA1(TO).Furthermore,theRamantensorofwurtziteAlNiscomparedwiththatofwurtziteZnOreportedinpreviouswork,revealingtheintrinsicdifferencesoflatticevibrationdynamicsbetweenAlNandZnO.

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  • 简介:我们建议被用来在single-j壳的Hamiltonian决定联合参数C的一个修改公式。与以前已知的公式比较,新公式改进在入侵者single-j层次和尼尔逊之间的协议。为在粒子转子模型以内的chiral乐队的研究,新联合参数将更加影响在马甲乐队之间切开的精力。

  • 标签: 耦合参数 壳模型 修正公式 粒子转子模型 哈密尔顿 尼尔森
  • 简介:Effectsofpressureand/ormagnetismonthecriticalsuperconductingtemperature(Tc)ofδ-MoNsinglecrystalwereinvestigatedusingaMaglabsystem.Theδ-MoNsinglecrystalwassynthesizedatextremeconditionsofhighpressureandhightemperature.Thecarrierdensityofδ-MoNsinglecrystalasafunctionofappliedpressurewasdeterminedusingHallcoefficientmeasurement.

  • 标签: 单晶合成 加压力 超导 磁性 载流子密度 ab系统
  • 简介:控制并且操作单个fluorophores的荧光具有对为它在改进分子的photonics和分子的电子学的表演的潜在的使用的最近的年的大兴趣,例如在基于单个分子的器官的轻射出的设备,单个光子来源,器官的地效果晶体管,和探针或传感器。这评论显示出单个器官的分子的荧光排放怎么能用金属性的nanostructures和electric-field-induced电子转移的本地电磁的领域被修改。荧光开关的Electric-field-induced荧光调整,磁滞现象,和成就详细被讨论。

  • 标签: 单分子荧光 有机电致发光器件 场效应晶体管 单分子传感器 电场诱导 分子电子学
  • 简介:Inthepresentstudythemembranefoulinginmicrofiltrationusedforcellharvestinginadeadendsystemhasbeeninvestigated.experimentalresultswereanalysedintermsofexitingmembranefiltrationmodelsandmembraneresistances.Thecakefiltrationmodel(CFM)andstandardblockingmodel(SBM)havebeenconsideredinthisstudy.Variousmembraneresistancesweredeterminedatdifferentprocessingtime,feedconcentrationandstirringspeed.Resistancestopermeationinthissystemincludefiltermedium,poreblocking,adsorption,cakelayerandconcentrationpolarization.

  • 标签: 微型过滤 薄膜堵塞 流动液体