简介:BACKGROUND:Conventionalmethods(suchasocclusiontherapy,finemanipulation,complementary,andalternativemedicine)takeeffectsslowly,aretimeandlaborconsuming,andhaveuncertaincurativeeffectsinthetreatmentofamblyopia.Perceptuallearning,anewmethodfortreatingamblyopia,improvestheabilitytoprocesssignalsfromthecerebralopticnervesystembyspecificvisualstimulationandvisuallearning,aswellasactivationofthevisualsignalpathwayutilizingbrainnervoussystemplasticity.OBJECTIVE:Thisstudyinvestigatedandevaluatedthecurativeeffectsofperceptuallearning,whichcandirectionallyincreasebrainplasticity,onthetreatmentofamblyopiainchildren.Therelationshipbetweencurativeeffectandtimewasalsoanalyzed.DESIGN:Aself-controlexperiment.SETTING:VisualScienceandOptometryCenter,People'sHospitalofGuangxiZhuangAutonomousRegion.PARTICIPANTS:Atotalof125amblyopicchildren(250amblyopiceyes),73males,52females,averaging(6±2)yearsofage,receivedtreatmentattheVisualScienceandOptometryCenter,People'sHospitalofGuangxiZhuangAutonomousRegionbetweenSeptember2006andFebruary2007andwererecruitedforthisstudy.Allchildrenpresentedwithnostructuraldiseaseoftheeyeballs.Writteninformedconsentfortherapeuticregimentswasobtainedfromeachchild'sparent.TheprotocolreceivedapprovalfromtheHospital'sEthicsCommittee.METHODS:Visualfunctionwastestedwithaperceptuallearningsystem(ResearchCenterforHumanHealthandDevelopmentofSunYat-senUniversity,NationalEngineeringTechniqueResearchCenterforMedicalCareImplement)forvisualnoise,positionnoise,contourdiscrimination,contrastsensitivity,gratingstereogram,andrandom-dotfusion.Thesetestshelpedtoevaluatetheefficiencyofvisualinformationprocessingofthesechildren,andtodeterminethedegreeofdefectsoftheopticnervecellsandtheconnectionsofvisualcorticalneurons.Accordingtoresultsofvisualfunct
简介:BACKGROUND:Traditionalsubhibernationtherapymayeasilycausecomplications,suchasrespiratorydepressionandhyportensionbecauseofapplicationofchlorpromazinehydrochlorideandpromethazineinalargedosage.OBJECTIVE:Toobservetherapeuticeffectofmodifiedsubhibernationtherapy(alterativeapplicationoffiveanticonvulsantsaccordingtothehalflife)onstatusepilepticusinchildrenwithsevereviralencephalitis(VE).DESIGN:Contrastobservation.SETTING:DepartmentofPediatrics,theFirstHospitalofJilinUniversity.PARTICIPANTS:Theparticipantsinpresentstudywere96patientswithsevereviralencephalitisincluding52boysand44girlswhoreceivedtreatmentintheDepartmentofPediatrics,theFirstHospitalofJilinUniversityfromFebruary2000toMarch2006.AllchildrenmetthediagnosticcriteriaofZhufutongPracticePediatrics(theseventhedition).Twoweeksago,theyevergotupperrespiratoryinfectionorenteronitisandsoonbeforetheonset,spiritabnormal,behaviordisorder,limbsactdisorder,vomit,headache,convulsion,nervoussystemmasculinesignssuchaslimbsactdisord,autonomicnervedamagemanifestation,brainnervepalsy,dysreflexia,meningealirritationsign,cerebrospinalfluidandelectroencephalography(EEG)abnormity.Allparentsprovidedtheconfirmedconsent.Thepatientswererandomlydividedintocontrolgroup(n=40)andexperimentalgroup(n=56).METHODS:Patientsinthecontrolgroupreceivedanticonvulsion,icecompressandroutinetreatment.Theconvulsionwastreatedwithfivedrugs:0.5mg/kgwinterminandphenergan,respectively,100g/Lchlorpromazinehydrochloride(0.5mL/kg),5mg/kgluminal,0.3mg/kgansiolin.Whenconvulsionattacked,thosefivedrugsweregivenalternatively;however,thosewerenotgiveniftheconvulsiondidnotattack.Childrenintheexperimentalgroupweretreatedwithimprovedsubhibernationtherapybasedonroutinetreatment.Thedosagesofanticonvulsantswereasthesameasthoseinthecontrolgroup.Bas
简介:BACKGROUND:Theuseofacupuncturehasreceivedrecognitiontoeffectivelytreatcerebralpalsy.Moreover,musictherapycanbeusedtomodifytreatmentofcerebralpalsy.OBJECTIVE:Tostudytheeffectsofcombinedtreatmentusingacupunctureandmusictherapyongrossmotorfunctionmeasure(GMFM)ofchildrenwithcerebralpalsy,comparedwithacupuncturetreatmentalone.DESIGN,TIMEANDSETTING:Randomized,controlled,clinicalstudy.TheexperimentwasconductedinShenzhenHospitalofTraditionalChineseMedicinebetweenJanuary2007andSeptember2007.PARTICIPANTS:AllchildrenwithcerebralpalsyinthetrialwerefromtheoutpatientdepartmentofShenzhenHospitalofTraditionalChineseMedicine.Thechildrenwererandomlydividedintotwogroups:30childreninGroupBreceivedacupunctureandmusictherapy,while30childreninGroupAreceivedonlyacupuncturetherapy.METHODS:SubjectsinGroupsAandBreceivedacupuncturebasedonsyndromedifferentiation.Themainacupointswerenecessaryforallparticipants.Atfirst,flashneedlingwasappliedtotheacupoints.Fortheremainingacupoints,thetechniqueoftransverseneedlingwasappliedtotheheadacupoints,andperpendicularneedlingwasusedfortheotherpoints.Theinsertedneedlesweretwirledandthenmaintainedfor30minutes.Theneedlewastwirledforonesecondeveryother10minutes,withoutreinforcing-reducingtechniques.Thetherapywasperformedeveryotherday.Thetrialconsistedofthreeperiodseach,andlastedfor84days.SubjectsinGroupBreceivedmusictherapy.Theylistenedtomusicthattheypreferredwhileacupuncturewasbeingperformed.Followingacupuncture,theywereallowedtoperformmusicalactivities,suchaspercussion,singing,anddancing.Themusictherapywasscheduledforonehour,includinglisteningtomusicfor30minutesandmusicactivitiesfor30minutes.MAINOUTCOMEMEASURES:ThecomprehensivefunctionalevaluationscaleofcerebralpalsyandtheGMFMwereappliedtotestsymptomsbeforeand