简介:准分子激光角膜切削术是九十年代在我国兴起的角膜屈光手术。近年来有诸多成功报道。但是,对于PBK术后的远期疗效乃是医生和患者极为关注的问题。我院自1996年4月开始用PRK治疗近视,效果较好,现对PRK术后5年以上患者进行随诊观察345例671眼,结果报告如下。资料与方法
简介:目的评价准分子激光原位角膜磨镶术(LASIK)治疗屈光性弱视的有效性、安全性和可预测性.方法回顾性分析2003年2月~2005年4月经LASIK治疗的24例(39眼)屈光性弱视病历.术前最佳矫正视力(BCVA)0.25~0.5,平均0.43±0.09.术后随访3~24月,平均12月.结果术后3月,裸眼视力达0.5~0.8及1.0眼分别为64.10%和2.58%,平均0.55±0.19;最佳矫正视力达0.5~0.8及1.0眼分别为61.54%和17.95%,平均0.65±0.22.残余球镜度≤±0.5D及>±0.5-≤±1.0D眼分别为38.46%和17.95%,平均-0.43±1.61D;残余柱镜度≤±0.5D和>±0.5~≤±1.0D眼分别为30.77%和41.03%,平均(-0.75D.0.69D).结论LASIK可有效矫正屈光性弱视的屈光度,有效提高视力,且具有良好的安全性和可预测性.
简介:患者男性,20岁,于2008年7月在我院行准分子激光原位角膜磨镶术手术.术前查屈光度:右眼-4.75DS-0.75DC×16°→1.0;左眼-5.0DS-0.5DC×159°→1.0.角膜厚度:右眼575μm,左眼582μm.角膜曲率:右眼K140.5D,K239.4D,左眼K140.9D,K240.3D.手术使用博士伦Z217型准分子激光治疗仪,采用Hansatome角膜板层刀制作角膜瓣,角膜瓣厚度110μm,蒂位于角膜上方,患者手术一切顺利,无游离角膜瓣及其他瓣的并发症.
简介:目的探讨准分子激光上皮下角膜磨镶术(LASEK)治疗高度近视术后半年疗效及其相关影响因素.方法对接受LASEK手术的109只术眼进行半年的跟踪观察,将术眼按术前屈光度分为三组,Ⅰ组(23眼):-6.00~-9.00D;Ⅱ组(56眼):-9.25~-12.00D;Ⅲ组(30眼):-12.00以上.对各组术后裸眼视力、HAZE、角膜曲率、回退率及眼压的变化进行了分析.结果1.术后视力各组均比术前有显著改善(P<0.001);2.术后HAZE发生率随度数增加而上升,且程度加重,但术后各组6个月时角膜混浊比第一个月有明显改善(P<0.01);3.术后各组回退率高,回退率随度数增加而上升;3.术后各组眼压与术前均有差异(P<0.001),术后各组第6个月时眼压有显著降低(P<0.01).结论LASEK手术对高度近视及超高度近视均有明显治疗作用,但对超高度近视预测性较差,HAZE发生率较高且回退率高.
简介:AIM:Tofindasimplemathematicalcorrelationbetweenthelensbasecurve(BC)andkeratometryfindings(krf).METHODS:Thisretrospectivestudyincluded400keratoconiceyes(350patients)previouslyfitwithrigidcontactlensesatanacademiceyecenteroverafiveyearperiod.Thepatientswereclassifiedintofivegroupsbasedonthekeratometryfindings(krf<7,krf:7-8,krf>8,krf-krs(differencebetweentwokeratometry;flatandsteep)=0.3-0.6,krf-krs>0.6mmasgroups1to5,respectively.MultivariatelinearregressionandMunro’scorrelationcoefficientwereemployedtodefertheformulas.RESULTS:Alinearcorrelationcouldbefoundinallgroupsexceptforpatientsingroup3.Forgroup1,BC=0.211×krf+5.904.Forgroup2,BC=0.456×krf+4.160.Forgroup4,BC=0.321×krf+5.219.Forgroup5,BC=0.337×krf+5.090.CONCLUSION:ThedevelopmentofnewformulasforRGPfittingenablesophthalmologiststoworkwithconfidenceandpreventsunnecessaryandfrequentlenstrials.Thecustomarylensfittingmethodsareneededtobereplacedbynewformulas,whichhelptosavetimeandcosts.
简介:我科采用选择性激光小梁成形术(selectivelasertrabeculoplasty,SLT)治疗穿透性角膜移植术(penetratingkeratoplasty,PKP)后继发性青光眼6眼,报告如下。
简介:AIM:Tostudytheimpactofscleralflapposition,underwhichtheposteriorchamberintraocularlenses(PC-IOL)weresulcus-fixedbytrans-scleralsuture,oncorneaastigmatism.METHODS:Twenty-sixaphakicorcataracteyeswerecomprisedinthisprospectivenoncomparativecaseseriesstudy.Eleveneyeshadtraumaticcataractremovedwithoutsufficientcapsularsupport,3hadblunttraumawithsubluxatedtraumaticcataract,8hadundergonevitreoretinalsurgeryand4hadcongenitalcataractremoved.Theaverageagewas54years(range21-74years),with17menand7women.ThefoldablePC-IOLwasfixedinsulcusbytrans-scleralsuture.TheincisionforIOLimplantationwasmade1mmposteriortolimbusalongthesteepestmeridianofcornea,whilescleralflapstoburytheknotsoftrans-scleralsutureweremadealongtheflattestmeridian.Allthesurgerieswereperformedbyasingledoctor(MaL),andthefollowupwasatleast13months(range13-28months).Thepreoperative,3monthsand1yearpostoperativecornealcurvaturealongthesteepestandflattestcorneameridianandoverallcorneaastigmatismwerecompared.RESULTS:Thecurvaturealongthesteepestmeridianchangedfrom44.25±2.22Dpreoperativelyto44.08±2.16Dat3monthspostoperatively,and43.65±5.23Dat1yearpostoperatively(P>0.05);thecurvaturealongtheflattestmeridianchangedfrom41.24±2.21Dpreoperativelyto43.15±3.94Dat3monthspostoperatively,and42.85±5.17Dat1yearpostoperatively(P<0.05);andthesurgeryinducedastigmatism(SIA)oncorneawascalculatedbyvectoranalysis,whichwas2.42±2.13Dat3monthspostoperatively,and2.18±3.42Dat1yearpostoperatively,thedifferencewasstatisticallysignificant(P<0.05).CONCLUSION:Thescleralflapmadealongtheflattestmeridian,underwhichtheposteriorchamberintraocularlenses(PCIOL)weresulcus-fixedbytrans-scleralsuture,cansteepenthecorneainvaryingdegrees,thusreducingpreexistingcornealastigmatism.
简介:AIM:Toestablishanuntransfectedhumancornealstromal(HCS)celllineandcharacterizeitsbiocompatibilitytoacellularporcinecornealstroma(aPCS).·METHODS:PrimaryculturewasinitiatedwithapurepopulationofHCScellsinDMEM/F12media(pH7.2)containing20%fetalbovineserumandvariousnecessarygrowthfactors.Theestablishedcelllinewascharacterizedbygrowthproperty,chromosomeanalysis,tumorigenicityassay,expressionofmarkerproteinsandfunctionalproteins.Furthermore,thebiocompatibilityofHCScellswithaPCSwasexaminedthroughhistologicalandimmunocytochemistryanalysesandwithlight,electronmicroscopies.·RESULTS:HCScellsproliferatedtoconfluence2weekslaterinprimarycultureandhavebeensubculturedtopassage140sofar.AcontinuousuntransfectedHCScelllinewithapopulationdoublingtimeof41.44hoursatpassage80hasbeendetermined.Resultsofchromosomeanalysis,morphology,combinedwiththeresultsofexpressionofmarkerproteinandfunctionalproteinssuggestedthatthecellsretainedHCScellproperties.Furthermore,HCScellshavenotumorigenicity,andwithexcellentbiocompatibilitytoaPCS.·CONCLUSION:Anuntransfectedandnon-tumorigenicHCScelllinehasbeenestablished,andthecellsmaintainedpositiveexpressionofmarkerproteinsandfunctionalproteins.Thecellline,withexcellentbiocompatibilitytoaPCS,mightbeusedforinvitroreconstructionoftissue-engineeredHCS.