简介:摘要ObjectiveThis study aimed to evaluate the effect of different combinations of rTMS and cognitive training (rTMS-COG) on PSCI and identify the optimal combination protocol.MethodsA cerebral infarction rat model was established by transient middle cerebral artery occlusion (tMCAO). The Morris water maze test was conducted to assess the cognitive function of rats. RNA sequencing and bioinformatics analysis were employed to study the underlying mechanisms.ResultsrTMS, COG and rTMS-COG all had beneficial effects on PSCI, while cognitive training immediately after rTMS (rTMS-COG0h) achieved a better effect than cognitive training 1 h and 4 h after rTMS, rTMS and COG. We identified 179 differentially expressed genes (DEGs), including 24 upregulated and 155 downregulated genes, between the rTMS-COG0h and rTMS groups. GO analysis revealed that the major categories associated with the DEGs were antigen procession and presentation, regulation of protein phosphorylation and axoneme assembly. KEGG analysis showed that the DEGs were enriched in processes related to phagosome, circadian entrainment, dopaminergic synapse, apelin signaling pathway, long-term depression, neuroactive ligand-receptor interaction, axon guidance and glucagon signaling pathway. PPI analysis identified Calb2, Rsph1, Ccdc114, Acta2, Ttll9, Dnah1, Dlx2, Dlx1, Ccdc40 and Ccdc113 as related genes.ConclusionsThese findings prompt exploration of the potential mechanisms and key genes involved in the effect of rTMS-COG0h on PSCI.
简介:在无线传感器节点的动态电源管理(DPM)是为减少闲散精力消费的一种著名技术。DPM由动态地基于事件出现的预言翻转它的单位的开/关地位控制一个节点操作模式。然而,后来,每个模式变化在它的自己的权利导致一些开销,保证DPM效率不是在展出有未知统计的非宿命论和无常的环境的吝啬的功绩。我们在这份报纸的解决方案套房,一起指了同样认知的电源管理(CPM),是向在统计上未知的设置的创新DPM的一次原则性的尝试并且给二不同分析保证。我们的第一个图案在面临非静止的事件过程时基于学习自动机和保证better-than-pure-chanceDPM。我们的第二个解决方案迎合事件出现可以在雇用一个对手的人物的甚至更一般的设置。在这种情况中,我们以节点在依靠一个no-external-regret过程以一种联机方式学习它的得最高分的战略策略的一场重复零和的比赛与它的环境提出单个尘埃的相互作用。我们进行数字实验以网络一生和事件损失百分比测量我们的计划的表演。
简介:Purpose:Thisstudyaimedtoinvestigatewhetherworkloadintensitymodulatesexercise-inducedeffectonreactiontime(RT)performances,andmorespecificallytoclarifywhethercognitivecontrolthatplaysacrucialroleinrapiddecisionmakingisaltered.Methods:FourteenparticipantsperformedaSimonTaskwhilecycling20minatalight(firstventilatorythreshold,VT1e20%),moderate(VT1),orveryhard(VT1t20%)levelofexercise.Results:After15minofcycling,RTsarefasterthanduringthefirst5minofexercise.ThisbenefitdoesnotfluctuatewiththeintensityofexerciseandenlargesasRTlengthens.Despiteanumericaldifferencesuggestingagreaterfacilitationduringmoderateexercise(16ms)thanduringalightexercise(10ms),thebenefitisnotstatisticallydifferent.Interestingly,wedidnotobserveanysignsofworseningonRToronaccuracyduringveryhardexercise.Conclusion:Cognitivecontrolisextremelyrobustandappearsnottobeaffectedbytheintensityofexercise.Theselectiveinhibitionandthebetween-trialsadjustmentsareeffectivefromthebeginningtotheendofexercise,regardlessoftheworkloadoutput.
简介:ThesecondaryusageofspectrumhasbeeninvestigatedinCognitiveRadio(CR)networktoresolvingthespectrumscarcityissueinwirelesscommunication.WhenPrimaryUsers(PU)whoownthespectrumappear,spectrumhandoffisneededtomaintainthecommunicationsofSecondaryUsers.ButthedecisionmakingofspectrumhandoffisachallengeissueforCRnetwork,becausetheinputofdecisionmaking,whichobtainthroughspectrumsensing,isheterogeneousandinexact.Inthispaperwewillusefuzzylogiccontroltheorytosolvethisissueandmakeuseofnewinformationforhandoffoperation:theprobabilityofPU'soccupancyatacertainchannel.Ournewalgorithmcanmakemoreintelligentdecisioncomparedtosimpletraditionalspectrumhandoffdecisionmakingandreducetheprobabilityofspectrumhandoff,alsotheperformanceofSU'scommunicationcanbeenhanced.
简介:Accordingtothefundamentaltheoryofvisualcognitionmechanismandcognitivepsychology,thevisualpatternrecognitionmodelisintroducedbriefly.Threepatternrecognitionmodels,i.e.template-basedmatchingmodel,prototype-basedmatchingmodelandfeature-basedmatchingmodelarebuiltanddiscussedseparately.Inaddition,theinfluenceofobjectbackgroundinformationandvisualfocuspointtotheresultofpatternrecognitionisalsodiscussedwiththeexampleofrecognitionforfuzzylettersandfigures.
简介:Theeffectofacuteexercise,asingleboutofexercise,oncognitiveperformancehasattractedmuchattention.ThefirstnarrativereviewofthisliteraturewasconductedbyTomporowskiandEllis.1Intheirsummary,theauthorsconcludedthatacuteexercisefacilitatescognitiveperformance;however,theyemphasizedthatthestudiesatthattimewereatheoreticaland
简介:Background:Attentiondeficithyperactivitydisorder(ADHD)isacommonchildhooddisorderthataffectsapproximately11%ofchildrenintheUnitedStates.Researchsupportsthatasinglesessionofexercisebenefitscognitiveperformancebychildren,andalimitednumberofstudieshavedemonstratedthattheseeffectscanalsoberealizedbychildrenwithADHD.ThepurposeofthisstudywastoexaminetheeffectofacuteexerciseoncognitiveperformancebychildrenwithandwithoutADHD.Methods:ChildrenwithandwithoutADHDwereaskedtoperformcognitivetaskson2daysfollowingtreatmentconditionsthatwereassignedinarandom,counterbalancedorder.Thetreatmentconditionsconsistedofa30-mincontrolconditionon1dayandamoderateintensityexerciseconditionontheotherday.Results:ExercisesignificantlybenefitedperformanceonallthreeconditionsoftheStroopTask,butdidnotsignificantlyaffectperformanceontheTowerofLondonortheTrailMakingTest.Conclusion:childrenwithandwithoutADHDrealizebenefitsinspeedofprocessingandinhibitorycontrolinresponsetoasessionofacuteexercise,butdonotexperiencebenefitsinplanningorsetshifting.
简介:TheEnglishconstruction'XandY'referstothecoordinationoftwowordswithandasconjunction,XandYbeingofthesamepartofspeechandparallelmeanings.ThispaperisacognitivestudyofthelinearorderoftheEnglishconstruction'XandY'fromtheperspectivesofcognitivesalience,cognitiveiconicity,andcognitionofformalrules.Thelinearcharacteristicsof'XandY'arerevealedasfollows:1)salience-downgradingorder;2)chronologicaliconicity;3)cognitionofalphabeticorderandprosodicorder.
简介:Purpose:Toinvestigatewhetherathleteswhoengageindifferentmodesofsportstrainingcorrespondinglyexhibitdifferentpatternsofperformanceongeneralcognitiontasks.Methods:Sixtyparticipantswererecruitedintoanendurance,motoricallycomplex,orcontrolgroup,andwereadministeredaseriesofphysicaltestsandneuropsychologicalassessments.Results:Athletesintheendurancegroupdemonstratedthehighestlevelsofcardiovascularfitnessandthoseinthemotoricallycomplexgroupexhibitedthehighestlevelsofmotorfitness.Nonetheless,nodifferencesincognitiveperformancewereobservedbetweenthe3groups.Conclusion:Thesefindingsindicatethatthemodeofsporttraining,whichresultsineitherhighcardiovascularorhighmotorfitness,bearsnorelationshiptomeasuresofgeneralcognitionineliteathletes.Thepresentfindingssuggestthatcoachesandathletictrainersshouldbeencouragedtomonitorathletes’stresslevelsduringtraininginordertomaximizethebeneficialeffectsofsuchtrainingongeneralcognitiveperformance.