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181 个结果
  • 简介:Therehasbeenaparadigmshiftinmedicineawayfromtradition,anecdoteandtheoreticalreasoningfromthebasicsciencestowardsevidence-basedmedicine(EBM).Inpalliativecarehowever,statisticallysignificantbenefitsmaybemarginalandmaynotberelatedtoclinicalmeaningfulness.Thetypicaltreatmentvs.placebocomparisonnecessitatedby‘goldstandard'randomisedcontrolledtrials(RCTs)isnotnecessarilyapplicable.Thecomplexmultimorbidityofendoflifecareinvolvesconsiderationsofthepatient'sphysical,psychological,socialandspiritualneeds.Inaddition,thefieldofpalliativecarecoversaheterogeneousgroupofchronicandincurablediseasesnolongerlimitedtocancer.Adequatesamplesizescanbedifficulttoachieve,reducingthepowerofstudiesandhighattritionratescanresultininadequatefollowupperiods.Thisreviewusesexamplesofthemanagementofcancer-relatedfatigueanddeathrattle(noisybreathing)todemonstratethecurrentstateofEBMinpalliativecare.ThefutureofEBMinpalliativecareneedstobeasdiverseasthepatientswhoultimatelyderivebenefit.Non-RCTmethodologiesofequivalentquality,validityandsizeconductedbycollaborativeresearchnetworksusinga‘mixedmethodsapproach'arelikelytoposethecorrectclinicalquestionsandderiveevidencebasedyetclinicallyrelevantoutcomes.

  • 标签: 治疗 应用 循证医学 临床意义 随机对照试验 医学模式
  • 简介:Inthispaper,firstlywedemonstratetheuseofnodaladmittancematrixtoconvertalow-passband-passfilterbasedonoperationalamplifier(op-amp)toacircuitbasedonasecond-generationcurrentconveyor(CCII).Thistechniqueallowsustogeteightpresumptionsoffiltercircuits.Secondly,wepresentanovelarchitecturecircuitofCCII,whichcanoperateatlowsupplyvoltageof±0.75V.AllsimulationsareperformedbyTSPICEmodels.ThesimulationresultsshowthatthiscircuithasalowimpedanceatterminalX(RX=1.01Ω),averyhighinputimpedanceatterminalY,andwidebandwidthcurrentandvoltage.Thecenterfrequencyoftheproposedfilterisvariableontheinterval[157kHz,196MHz].

  • 标签: 运算放大器 滤波电路 CCII 电压模式 放大器电路 第二代电流传送器
  • 简介:Thispaperextendstheresourcedragstudiesbyempiricallyinvestigatinghowspatialfactorsaffecttheregionaleconomicgrowth.Usingspatialpaneleconometricmodels,thispaperestimatesthedraggingeffectofenergyresourcesoftheYangtzeRiverDeltametropolitanareas.WefindthatthegrowthdragofenergyintheYangtzeRiverDeltaisabout6%onaverage,whichmeansthatenergyconstraintsdecreasetheeconomicgrowthby6%annually,higherthanthenationallevelthathasbeenpreviouslymeasuredintheliterature.Thisresulthastakenintoaccounttheimpactofneighboringcities’economicdevelopment,soastoobtainamoreaccurateestimate.Basedonthesemeasurementresults,weproposesomepolicyrecommendations.

  • 标签: ECONOMIC growth DRAGGING EFFECT SPATIAL econometri
  • 简介:TheunsteadycavitationevolutionaroundtheClark-Yhydrofoilisinvestigatedinthispaper,byusinganimprovedfilter-basemodel(FBM)withthedensitycorrectionmethod(DCM).Toimprovethepredictionaccuracy,thefilterscaleisadjustedbasedonthegridsize.Thenumericalresultsshowthatasmallfilterscaleiscrucialfortheunsteadysimulationsofthecavitysheddingflow.ThehybridmethodthatcombinestheFBMandtheDCMcouldhelptolimittheoverpredictionoftheturbulentviscosityinthecavitationregiononthewallofthehydrofoilandinthewake.Thelargevalueofthemaximumdensityratio?l/?v,clippromotesthemasstransferratebetweentheliquidphaseandthevaporphase,whichresultsinalargesheetcavitylengthandthevaporfractionriseinsidethecavity.Thecavitypatternspredictedbytheimprovedmethodareverifiedbytheexperimentalvisualizations.Thetime-averagelift,thedragcoefficientandtheprimaryoscillatingfrequencyStforthecavitationnumber?=0.8,theangleofattack,?=8o,ataReynoldsnumberRe=7?105are0.735,0.115and0.183,respectively,andthepredictederrorsare3.29%,3.36%and8.93%.Thetypicalthreestagesinonerevolutionarewell-captured,includingtheinitiationofthesheet/attachedcavity,thegrowthtowardthetrailingedge(TE)withthedevelopmentofthere-entrantjetflow,andthelargescalecloudcavityshedding.ItisobservedthatthecloudcavitysheddingflowinducesthevortexpairsoftheTEvorticesinthewakeandthesheddingvortices.Thepositivevorticityvortexofthere-entrantjetandtheTEvorticesinteractsandmergeswiththenegativevorticityvortexoftheleadingedge(LE)cavitytoproducethesheddingflow.

  • 标签: 非定常特性 滤波器库 空化数 数值分析 模型 基础
  • 简介:Thereisgrowinginterestinthecorrelationbetweenworkingtimeandenvironmentalpressures,butpriorempiricalstudiesmostlyfocusedonstaticmethodologies.Thisarticleuseddynamicpanelregressionapproachestoexamineandcomparetherelationshipamongwestern,southern,andnorthernEuropeancountriesovertheperiod1970-2010,andprovedtheexistenceofstronglysignificantrelationshipsinallmodels.Furthermore,thisarticledetectedtherelationshipbetweenworkinghoursandenvironmentalindicators(carbonemissionandenergyuse)atdifferentphases.Wecontributetoafurtherunderstandingoftheenvironmentaleffectsoftheworkingtimereductionpolicybycomparingthedifferencesamongvariousperiodsandcountrygroupsinasystemgeneralizedmethodofmoments(GMM)dynamicframework.

  • 标签: working time ENVIRONMENTAL PRESSURE CARBON EMISSION
  • 简介:ETL(Extract-Transform-Load)通常包括三个阶段:抽取,转变,并且装载。在造数据仓库里,它起数据注射的作用并且是最费时间的活动。因此改进ETL的表演是必要的。在这份报纸,一条新ETL途径,电话(Transform-Extract-Load)被建议。电话途径使用虚拟表格在抽取舞台和装载舞台前认识到转变阶段,在存储从每迥异的来源数据系统提取的未加工的数据的数据阶段区域或阶段数据库外面。电话途径减少数据传播负担,并且从存取层改进询问的性能。试验性的结果基于我们的建议基准证明电话途径可行、实际。

  • 标签: ETL 虚拟化 临时数据库 数据仓库 原始数据 数据传输
  • 简介:基于颤动的精力harvester是实质上在一个有限频率范围工作的一个共鸣器。增加工作频率范围是一个挑战性的问题。这份报纸为提高经由内部回声收获的精力揭示新奇可能性。内部回声精力harvester被建议。刺激连续地作为Gaussian白噪音,一个秒顺序过滤器定义的有颜色的噪音,狭窄乐队的噪音,和指数地相关的噪音被假定。相应平均root-mean-square产量电压被计算。数字结果证明内部回声增加操作带宽和产量电压。

  • 标签: 共振 收集器 电能量 频率范围 输出电压 高斯白噪声
  • 简介:Ghostimagingcouldbeusedtomakeaquickidentificationoforthogonalobjectsbymeansofphotocurrentcorrelationmeasurements.Inthispaper,weextendthemethodtoidentifynonorthogonalobjects.Inthemethod,anobjectisilluminatedbyonephotonfromanentangledpair,andtheotheroneisdiffractedintoaparticulardirectionbyapre-establishedmultiple-exposurehologramintheidlerarm.Bythecorrelationmeasurements,thenonorthogonalobjectinthesignalarmcouldbediscriminatedwithinaveryshorttime.Theconstraintsfortheidentificationofnonorthogonalobjectsarepresented,whichshowthatthenonorthogonalobjectscanbediscriminatedwhentheoverlappingportionbetweenanytwoobjectsislessthanhalfofalltheobjectsintheset.Thenumericalsimulationsfurtherverifytheresult.

  • 标签:
  • 简介:Theinstabilityofboreholewallisalwaysadifficultquestionindrillingboreholeprogress.Itincreasesthecostofproductionandprolongsproductioncycle.Soithasasignificantresearchvalue.Consideringtheeffectofmudpressureandporepressureonthestabilityofboreholewall,thispaperestablishesamathmodelbyapplyingthetwo-dimensionalbondtheoryofBiot.Itappliesthemethodofthenumericalsimulationtoanalyzetheeffectofmudpressureandporepressureonthestabilityofboreholewall.Thesimulationresultsshowthatthemudpressureimposesgreatinfluenceonstressfieldandonthedeformationofboreholesoil,whichprovidesatheoreticalbasisduringthedrillingprocesstoavoidtheinstabilityoftheboreholeandtostudyhowtoselectreasonablemudandmudpressure.

  • 标签: 井壁失稳 ABAQUS 稳定性分析 井壁稳定性 泥浆压力 孔隙压力
  • 简介:Duringrecentyears,somenotionsabouttaskshavebeenconsideredasthemajorpartofanalysisindifferentteachingapproachesandteachersarebeingmoreinterestedintheuseoftaskbasedapproachbothinforeignandinsecondlanguageteaching.Themaingoalofthisarticleistointroduceanddiscusssomemajorprinciplesoftask-basedlanguageteachingandindicateshowteacherscanapplythemintheircurriculum.

  • 标签: TASK TASK-BASED APPROACH LANGUAGE TEACHING
  • 简介:Traumaticinjuriestospinalcordelicitdiversesignalingpathwaysleadingtounselectiveandcomplexpathologicaloutcomes:deathofmultipleclassesofneuralcells,formationofcysticcavitiesandglialscars,disruptionofaxonalconnections,anddemyelinationofsparedaxons,allofwhichcancontributemoreorlesstodebilitatingfunctionalimpairmentsfoundinpatientswithspinal

  • 标签: 脊髓损伤 损伤修复 移植治疗 存活率 干细胞 植物
  • 简介:LanthanidedopedNaYF4microcrystalsweresynthesizedviaafacilehydrothermalmethod.MulticolorupconversionluminescencewasobservedinNaYF4microcrystalsdopedwithYb3+/Er3+,Yb3+/Tm3+,andYb3+/Er3+/Tm3+undertheexcitationof980nminfraredlight.Importantly,theexcitationpowerdensitydependenceofupconversionemissionintensityindicatedclearlytheenergytransferfromTm3+toEr3+ionsundertheexcitationoflowpowerdensity(5×102–9×102W/cm2).Meanwhile,theinverseenergytransferfromEr3+toTm3+ionsundertheexcitationofrelativelyhigherpowerdensity(4.1×104–4.9×104W/cm2)wasalsorevealed.ThiswasadirectevidenceforreversibleenergytransferbetweenEr3+andTm3+ions.Undertheexcitationofhighpowerdensity(4.1×104–4.9×104W/cm2),darksensitizerswerealsomotivatedsothatthebottleneckeffectofhighconcentrationYb3+iondopingwasbroken.ThiswasthemainreasonforrealizinghighupconversionefficiencyofthesampleswithheavydopingofYb3+ion.

  • 标签: 上转换发光 离子掺杂 能量转移 TM 微晶 证据
  • 简介:第四代(4G)无线通讯系统被部署了或不久在许多国家被部署。与无线移动设备和服务的爆炸,然而,仍然有一些挑战,不能甚至被4G提供,例如光谱危机和内部房间的干扰。电信操作符转弯了承诺自己分享可得到的资源,包括硬件和软件资源。因此与相互的基础结构,‘integration’应该被加亮,特别在第五代(5G)被期望到的无线系统超过2020被部署。在文章的作者建议了潜在的细胞的体系结构,并且讨论了内部操作员的收音机接口为5G的基于的同步(肋骨)无线通讯系统。内部操作员的肋骨和典型情形的一个计划,与相应干扰的分析一起被给。分享的参数,内部操作员的肋骨的发信号的协作和为肋骨的信号(RS)设计也是的听的引用的分析执行了。

  • 标签: 电信运营商 无线接口 同步 无线通信系统 小区间干扰 无线移动设备