简介:Teacher:Whyareyoulateforschool?Boy:ItwaslatewhenIstartedfromhome.Teacher:Thenwhydidn’tyoustartearly?Boy:Itwasalreadytoolatetostartearly,sir.注释:belateforschool上学迟到startv出发alreadyadv已经too…to太……以至于不能…
简介:CorticosteroidsandimmunomodulatorshavebeenthemainstaytherapiesforCrohn’sdisease.Corticosteroidsarehighlyeffectivetocontrolsymptomsintheshort-term,buttheyarenoteffectiveinmaintainingremission,theyhealthemucosainareducedproportionofcases,andlong-timeexposureisassociatedwithanincreasedriskofinfectionsandmortality.Immunomodulators,azathioprineandmethotrexate,healthemucosainahigherproportionofpatientsthatcorticosteroidsbuttheironsetofactionisslowandtheybenefitlessthanhalfofpatientswithCrohn’sdisease.Inthelastdecade,medicaltherapyforCrohn’sdiseasehasexperiencedaremarkablechangeduetotheintroductionofbiologictherapy,andparticularlytheuseofanti-tumournecrosisfactor-alphaagents.Infliximab,adalimumab,andcertolizumabpegolhavedemonstratedefficacyforinductionandmaintenanceofremissioninactiveCrohn’sdisease.TheseagentshaveraisedthebarforwhatisasuitablesymptomaticresponseinCrohn’sdiseaseandmodificationofthenaturalhistoryofthediseasehasbecomeamajorgoalinthetreatmentofCrohn’sdisease.Thereareseveraldataintheliteraturethatsuggestthatearlyuseofbiologictherapyandachievementofmucosalhealingcontributetodiseasecoursemodification.However,manyquestionsonearlybiologicaltherapyforCrohn’sdiseaseremainstillunanswered.
简介:TheobjeetiveofthisbasicandtcctonicrcscarchistoclarifythocauscsofabsoluteuphcavalofJapancsclslandsinlatcPlcistoccnetoHoloccnoagcs.InmanyrcgionsofhighlandsofJapancscIslands,fiocksofcau1drons,lcssthan2okmindiamctcr,wcrcforn1edintcndiffcrcnttimcsduringMioccnctoPlioccnc-Quatcrnaryagcs(Fujita,l972,l99l).W
简介:<正>1.IntroductionWhenaddressinglanguagecohesion,anattemptmustbemadetoidentifyhowlanguageisusedtocreatecohesiveandcoherentcommunication,orhowoneutterancefollowsanother.WilliamLabovdescribesthetaskathand,statingthat‘thefundamentalproblemofdiscourseanalysis1istoshowhowoneutterancefollowsanotherinarational,rulegovernedmanner—inotherwords,howwe
简介:ChinaisrichinMiddleandCarboniferousfossilcorals.Thecoralfaunasindifferentregionshavevaryingcharacteristicsandcanbedividedintodistinctassemblages.ThecoralfaunainSouthChinaisdominatedbytheorderCaninidaandcontainsnumerousendemicelements;thatinNorthChinahasalotofMiddleCarboniferouscoralswhicharemonotonousinspecies,withLateCarboniferoussolitarycoralsbeingpredominant.ThecoralfaunainJunggarmainlycontainslargebi-zonedsolitarycaninids,whilethatinsouthernKhinganissimilartothatinSouthChinaduetothepresenceofabundanttri-zonedcompoundcorals.InnorthernTibetthecoralfaunaisalsosimilartothatinSouthChina,butinsouthernTibetitisofacold-watertype.Therefore,theMiddleandLateCarboniferouscoralgeographyofChinacanbedividedintotheTethys,BorealandGondwanaRealms.
简介:1.Introduction.ThelateMesozoicEastAsiancontincntalmarginwasamobilebeltsimilartorecentcontinentalares,buthadaconsidcrablcwidthmorcthan2,oookm’Thispapcrdcscribcstbegeometryofthemobilebc1t,anddiscusscsthckincmaticsanddynamics-Itwillclarifythatthermalp1umcundcrtbeEastAsiancontincntplaycdanhoportantrolei
简介:KazkeaertefaultzoneisrecognizedasanimportantboundarybetweenPamirandTianshanCenozoicMountainbeltsinthewestofTarimBasin.Itisanactivethrustfaultandcanbedividedintothreesegmentsfromthewesttoeast:Jilekeroutefaultzone,Wuqiaearthquakefaultzone,MushifaultzoneaftergeologicalinvestigatingandmappingalongPamirpiedmont.Basedonthefaultedlandformaswellasdeformationanddisplacementofyoungdepositlayers,theslipratesofKazkeaertefaultzonesincethelateQuaternaryarebrieflystudied.Theresultshowsthattheaveragesliprateoffaultisdifferentiatealongdifferentsegments.
简介:Causesinducingsubacutethyroiditishavebeenunclear,butclinicallyitistreatedmostlywithcorticalhormones.Inthepresentpaper,itwasreportedthatonecaseofsubacutethyroiditiswithhyperthyodismatthelatestagewascuredwithacupunctureatRenying(ST9),Fengchi(GB20),Jiajipontsontheneckandotherpoints.Inthetreatment,differentiationofsymptomsandsignswascombinedwithdifferentiationofdisease,selectionofproximalacupointswascombinedwithselectionofdistalacupoints.Thepatientwastreatedinaccordancewithhisphysique.Therefore,thetherapeu-ticeffectswereobtainedrapidly.