简介:he will have regrets about having never gone back and traveling down the roads he did not take. Yet he remains proud of his decision and he recognizes that it was this path that he chose that made him turn out the way and he did and live his life the way in which he lived. "I took the road less trvaelled by and that had made all the difference." To this man,and having perhaps the better claim." What made it have the better claim is that "it was grassy and wanted wear." It was something that was obviously not for everyone because it seemed that the majority of people took the other path therefore he calls it "the road less travelled by". The fact that the traveler took this path over the more popular,"And sorry I could not travel both..." It is always difficult to make a decision because it is impossible not to wonder about the opportunity cost
简介:he will have regrets about having never gone back and traveling down the roads he did not take. Yet he remains proud of his decision and he recognizes that it was this path that he chose that made him turn out the way and he did and live his life the way in which he lived. "I took the road less trvaelled by and that had made all the difference." To this man,and having perhaps the better claim." What made it have the better claim is that "it was grassy and wanted wear." It was something that was obviously not for everyone because it seemed that the majority of people took the other path therefore he calls it "the road less travelled by". The fact that the traveler took this path over the more popular,"And sorry I could not travel both..." It is always difficult to make a decision because it is impossible not to wonder about the opportunity cost
简介:Inthispaper,thewaves’breakingintheleewavesissuccessfullysimulatedbytheatmosphericmesoscalenumericalmodelwithasecond-ordertur-bulentclosure.Itisfurtherprovedthattheturbulenceinthewave-breakingregionplaystheroleofintensemixingfortheaveragefield,whichleadstothetrappingofupwardpropagatingwavesandthuspromotesthedevelopmentofthedownslopewind.Theturbulentstructureinthewave-breakingregionisdiscussedandthefol-lowingconclusionsareobtained:(1)Inthewave-breakingregion,theturbulentheatfluxestransferfrominsidetooutsideandtheturbulentmomentumfluxestransferfromoutsidetoinside.(2)Inthewave-breakingregion,theturbulentenergymainlycomesfromthewindshearandthebuoyancypromotestheturbulentdevelopmentonlyinpartoftheregion.(3)Intheupperpartofthewave-breakingregion,theturbulentmomentumfluxesbehaveasacounter-gradienttransfer.(4)Theturbulentmixinginthewave-breakingregionisnon-local.
简介:摘要目的了解IgA肾病的发病率,不同性别及年龄的发病情况,IgA肾病患者主要出现的临床表现以及与IgA肾病Lee氏分级的关系。方法收集IgA肾病的患者的性别,肾穿时的年龄,身高,体重,血压,血常规,肝功能,肾功能,肝炎标志物,尿常规,24小时尿蛋白定量,肾活检病理资料。结果IgA肾病占肾活检率的23.7%;IgA肾病占原发性肾小球疾病的30.9%;IgA肾病以20-29岁和30-39岁两个年龄段发病最多;男性与女性的性别比例为2.211;IgA肾病患者的血压与年龄呈秩相关,血压与24小时尿蛋白定量呈秩相关,血压与尿酸呈秩相关,Lee氏分级与血压呈秩相关,Lee氏分级与24小时蛋白尿呈秩相关;Lee氏分级与尿酸呈秩相关。结论Lee氏分级与高血压的发病率,24小时尿蛋白定量,高尿酸血症的发病率存在一定的相关性。
简介:目的探讨血清胱抑素C(CysC)与IgA肾病(IgAN)Lee氏分级和牛津分型的相关性,为评估该病严重程度提供依据。方法观察2013年1月—2018年1月在上海中医药大学附属龙华医院肾病科进行肾穿刺活检证实为原发性IgAN的患者191例。根据Lee氏分级与牛津分型间质纤维化与小管萎缩(T)分级分为轻、中、重3组,另根据牛津分型新月体(C)分级分为2组,观察患者血清CysC、血白蛋白(Alb)、血肌酐(SCr)、尿素氮(BUN)、尿酸(UA)、24h尿蛋白及24h尿微量白蛋白水平,采用CKD-EPI公式估算肾小球滤过率(eGFR),分析血清CysC与Lee氏分级、牛津分型之间的关系。结果Lee氏分级与T的分组中,随着病理损伤程度的加重,患者血清CysC、SCr、BUN水平逐渐升高,eGFR水平逐渐降低(P<0.01)。Spearman相关分析显示血清CysC与Lee氏分级、牛津分型中T分级呈正相关(r=0.768,r=0.624,均P<0.01),与eGFR呈负相关(r=-0.804,P<0.01);上述相关性在多元线性回归中得到证实。含有新月体的患者,血清CysC水平较不含新月体患者的水平升高(P<0.01),Spearman相关分析显示二者亦有一定的相关性(r=0.181,P<0.01),但多元线性回归提示二者相关性不强,故仍需进一步证实。结论血清CysC可作为反映IgAN早期病理损伤等级尤其是间质小管损伤程度的敏感性指标。
简介:Friedberg,LeeandZhao(FLZ)proposedamethodforeffectivelyevaluatingtheeigenenergiesandeigenwavefunctionsofquantumsystems.Inthiswork,westudyseveralspecialcasestoinvestigateapplicabilityofthemethod.Concretely,wecalculatetheground-stateeigenenergyoftheHellmannpotentialaswellastheCornellpotential,andalsoevaluatetheenergiesofthesystemswherelineartermisaddedtotheCoulombasaperturbation.Theresultsobtainedinthismethodhaveasurprisingagreementwiththetraditionalmethodorthenumericalresults.Sincetheresultsinthismethodhaveobviousanalyticitycomparedtothatinothermethods,andbecauseofthesimplicityforcalculationsthismethodcanbeappliedtosolvingtheSchrodingerequationandprovidesusabetterunderstandingofthephysicalessenceoftheconcernedsystems.ButmeanwhileapplicationsoftheFLZmethodarerestrictedatpresent,especiallyforcertainpotentialforms,butduetoitsobviousadvantages,itshouldbefurtherdeveloped.
简介:摘要目的旨在探讨儿童IgA肾病(IgA nephropathy,IgAN)肾脏病理Lee氏分级与其临床特征的可能关系。方法回顾性分析了广州市妇女儿童医疗中心肾内科2017年7月至2020年12月收治的66例IgAN患儿的临床及肾脏病理Lee氏分级数据。统计学方法采用单因素方差分析、Kruskal-Wallis H检验、Spearman秩相关分析。结果本研究纳入的66例IgAN患儿中,男44例(66.7%),女22例(33.3%),男女比例2∶1,年龄(7.7±2.6)岁。66例IgAN患儿临床表现以血尿合并蛋白尿为主(49例),其次为孤立性血尿(16例),孤立性蛋白尿(1例);10例(15.2%)IgAN患儿有肾脏病家族史。肾脏病理以Lee氏Ⅲ级最常见,共39例(59.1%),其次为Ⅱ级17例(25.7%),Ⅳ级5例(7.6%),Ⅰ级3例(4.5%),Ⅴ级2例(3.0%)。不同Lee氏分级的患儿24 h尿蛋白定量(24 h-UP)、尿蛋白比尿肌酐、血清胱抑素C、肾小球滤过率(GFR)差异均有统计学意义(均P<0.05)。Spearman相关性分析显示,Lee氏分级与患儿的24 h-UP、尿蛋白比尿肌酐、血肌酐、尿素氮(BUN)、血清胱抑素C值间呈正相关(均P<0.05),与GFR呈负相关(P<0.05)。结论血尿合并蛋白尿是本次研究儿童IgAN最普遍的临床特征,Lee氏分级以Ⅲ级为主,患儿蛋白尿水平、肾功能指标与Lee氏分级间存在显著相关性。