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  • 简介:当你想请别人吃一个冰淇淋时,该怎么说呢?很简单,只要一句话就行了。I'lltreatyoutoicecream,小明把小强领到一个冷饮店。

  • 标签: 小学 英语 课外阅读 阅读材料
  • 简介:Findit!WhatcanPamandAmyget?ConversationA(AmyandPamareOutsidethemall.AmanWalksovertothem)

  • 标签: for ICE WHAT MALL over PAM
  • 简介:Hydroquinoneexertsrathergooddiscoloringeffectsintreatmentofsomepigmetarydermatosis.2%hydroquinonecreamdevelopedbydepartmentofpreparationinourhospitalwasappliedinourdepartmenttotreatpigmetarydermatosislikechloasma.Thesummarywasasfollowed:

  • 标签: 对苯二酚 皮肤病 黄褐斑 治疗 临床分析
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  • 简介:摘要飞机维修是航空系统要素不可缺少的,人为失误会给飞机的辐射安全和效率带来不利影响,在尽可能低的水平上维修差错控制,有必要建立一套可靠的维修人员错误概率预测模型。本文将认知可靠性和误差分析方法引入工程维修可靠性分析,第一次使用前一些添加和修改的方法,然后根据经验的法律符合工程的特点维护操作误差概率预测公式,最后到一个特定的飞机维修部门数据维护操作错误在2011年作为一个例子,这个公式来预测维护维修操作误差概率与历史数据分析,结果表明,该公式具有很强的可靠性和可用性。

  • 标签: CREAM模型 人误 机组资源管理
  • 简介:摘要:在我国汽车制造中,防错技术是一种全新的技术形式,而将此种技术进行应用的关键目的,实际上就是为了让各项构件与合格标准达成一致,以防止误差的产生。所以,在汽车减震器装配中应用防错技术的过程中,一定要全面了解并掌握各项内容,这样才能够让汽车减震器装配中各项数据的精确度得到进一步提升,以此避免出现误差的情况,从而使汽车减震器装配质量可以达到100%的合格率。

  • 标签: 汽车零部件 防错设计 实际应用
  • 简介:AbstractBackground:Benvitimod cream, a novel synthetic small molecule, was effective in treating mild-to-moderate plaque psoriasis. We conducted a phase III clinical trial to assess the efficacy and safety of benvitimod cream in patients with mild-to-moderate plaque psoriasis.Methods:We randomly assigned 686 patients (2:1:1) to receive 1% benvitimod cream, 0.005% calcipotriol ointment or placebo twice a day for 12 weeks. The primary efficacy end points were the percentage of patients with a 75% or greater reduction from baseline in the psoriasis area and severity index (PASI 75) score and with a score of 0 or 1 in static physician’s global assessment (sPGA) at week 12.Results:The results showed that 50.4% of patients in the benvitimod group achieved PASI 75, which was significantly higher than that in the calcipotriol (38.5%, P < 0.05) and placebo (13.9%, P < 0.05) groups. The proportion of patients achieving an sPGA score 0 or 1 was 66.3% in the benvitimod group and 63.9% in the calcipotriol group, which were both significantly higher than that in the placebo group (34%, P < 0.05). In the long-term follow-up study, 50.8% of patients experienced recurrence. After retreatment with 1% benvitimod, 73.3% of patients achieved an sPGA score of 0 or 1 again at week 52. Adverse events included application site irritation, follicular papules, and contact dermatitis. No systemic adverse reactions were reported.Conclusion:During this 12-week study, benvitimod cream was demonstrated with high effectiveness and safety in patients with mild-to-moderate plaque psoriasis.Trial Registration:Chinese Clinical Trial Registry (ChiCTR), ChiCTR-TRC-13003259; http://www.chictr.org.cn/showprojen. aspx?proj=6300.

  • 标签: Psoriasis Benvitimod Immune modulator Drug discovery 3 5-dihydroxy-4-isopropylstilbene
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