简介: [摘要 ] 目的 探讨乌司他丁在重症病毒性肺炎免疫调节治疗的临床疗效。 方法 回顾性分析 2017年 1月— 2019年 12月我院重症医学科收治的重症病毒性肺炎患者的临床资料,分析乌司他丁对患者免疫及预后的影响。结果 纳入 74例重症病毒性肺炎患者,死亡 19例( 25.7%) ;治疗组 36例,第 7天 CRP( 46.2±32.8) mmol/L、 HLA-DR( 60.02±12.08) %、 T-CD4+( 422±87) cell/L与第 0天的( 123±59.8) mmoL/L、( 41.22±15.90) %、( 220±54) cell/L间差异有统计学意义( P<0.05),且与对照组的( 34.1±11.8) mmol/L、( 42.06±14.08) %、( 326±69) cell/L间差异有统计学意义( t=1.781、 2.603、 2.527, P<0.05)。治疗组 28 d死亡 9例( 25.0%), VAP发生率为 21.77‰,低于对照组的 10例( 26.3%)( χ2=4.432, P=0.028)、 42.12%( χ2=0.017, P=0.897)。 结论 乌司他丁能改善重症病毒性肺炎患者的免疫功能,降低 VAP发生率,但无法改善预后。 [关键词 ] 重症病毒性肺炎 ;免疫干预 ;乌司他丁 [Abstract] Objective To investigate the clinical efficacy of ulinastatin in immunomodulatory therapy of severe viral pneumonia. Methods the clinical data of patients with severe viral pneumonia admitted to our hospital from January 2017 to December 2019 were retrospectively analyzed, and the effect of ulinastatin on immunity and prognosis of patients was analyzed. Results 74 patients with severe viral pneumonia were included, 19 (25.7%) died; There are 36 patients in the treatment group of 36 patients in the treatment group of 36 patients in the treatment group of 36 patients in the seventh day of CRP (46.2 ± 32.8) mmol / L, HLA-DR (60.02 ± 12.08), t-cd4 + (422 ± 87 ± 87) cell / L on the seventh day and (123 ± 59.8) mmol / L, (41.22 ± 15.90)%, (220 ± 54) cell / L (P < 0.05), and there are statistically significant differences between (34.1 ± 11.8) mmol / L, (42.06 ± 14.08)%, (326 ± 69) cell / L / L of the control group (t = 1.1.1.1.1.1.8) mmol / L, (42.06 ± 14.08 ± 14.08)%, (326 ± 69 781 2.603、 2.527, P<0.05)。 The incidence of VAP in the treatment group was 21.77 ‰, which was lower than that in the control group (26.3%) (χ 2 = 4.432, P = 0.028) and 42.12% (χ 2 = 0.017, P = 0.897). Conclusion Ulinastatin can improve the immune function of patients with severe viral pneumonia, reduce the incidence of VAP, but can not improve the prognosis.
简介:摘要:目的:分析药学干预对临床抗生素合理用药的干预效果。方法:抽取医院应用抗生素类药物进行治疗的患者190例做为研究对象,未经药学干预的95例患者做为对照组,接受药学干预的95例患者做为研究组。结果:研究组患者抗生素使用排名前三位的依次为阿奇霉素(21.05%)、头孢他啶(16.84%)、头孢哌酮/舒巴坦(13.68%),对照组患者抗生素使用排名前三位的依次为头孢哌酮/舒巴坦(25.26%)、头孢他啶(20.00%)、哌拉西林/他唑巴坦(12.63%)。研究组患者联合用药率、不合理用药率均明显低于对照组,病原学检测率明显上升,(P<0.05)。研究组患者住院时间和抗生素使用时间明显比对照组短,使用抗生素药物花费的金额明显比对照组低,(P<0.05)。结论:药学干预应用于临床抗生素的使用中可促进抗生素类药物的合理使用、减轻不合理用药风险、提升临床疗效、缩短患者住院时间、减轻患者经济方面的压力。
简介: 【摘要】 目的 探讨临床路径在猩红热患儿诊疗护理中的应用价值。方法 60例猩红热患儿, 随机分为对照组和临床路径组, 每组 30例。对照组患儿给予一般护理, 临床路径组患儿给予临床护理路径。比较两组患儿家属护理满意度 ;猩红热诊疗总时间、猩红热病情改善时间、治疗费用 ;护理前后生命质量指标以及心理健康指标 ;不良反应发生情况。结果 临床路径组患儿家属护理满意度为 100.00%( 30/30), 显著高于对照组的 70.00%( 21/30), 差异具有统计学意义( P<0.05)。护理前, 两组患儿生理职能、社会功能、躯体功能、整体健康以及焦虑、抑郁评分比较, 差异均无统计学意义( P>0.05)。护理后, 两组患儿的生理职能、社会功能、躯体功能及整体健康评分均明显高于护理前, 焦虑、抑郁评分均明显低于护理前, 且临床路径组患儿的生理职能、社会功能、躯体功能及整体健康评分均明显高于对照组, 焦虑、抑郁评分均明显低于对照组, 差异均具有统计学意义( P<0.05)。临床路径组患儿猩红热诊疗总时间、猩红热病情改善时间分别为( 8.41±3.12)、( 3.41±1.34) d, 均明显短于对照组的( 10.41±3.16)、( 6.24±1.01) d, 治疗费用( 5436.42±1343.22)元明显少于对照组的( 7636.86±1367.22)元, 差异均具有统计学意义( P<0.05)。临床路径组患儿不良反应发生率为 3.33%( 1/30), 明显低于对照组的 20.00%( 6/30), 差异具有统计学意义( P<0.05)。结论 猩红热患儿实施临床护理路径可获得良好效果, 能够显著提高患儿的生命质量, 减轻焦虑、抑郁情绪, 缩短治疗时间, 减少治疗费用, 提高患儿家属护理满意度。 【关键词】 临床路径 ;猩红热 ;诊疗护理 ;应用价值 [Abstract] Objective To explore the application value of clinical pathway in the diagnosis, treatment and nursing of scarlet fever children. Methods 60 children with scarlet fever were randomly divided into control group and clinical pathway group, 30 cases in each group. The control group was given general nursing, the clinical pathway group was given clinical nursing pathway. The nursing satisfaction, the total time of diagnosis and treatment, the time of improvement of scarlet fever, the cost of treatment, the indicators of life quality and mental health before and after nursing, and the occurrence of adverse reactions were compared between the two groups. Results the nursing satisfaction of family members in clinical pathway group was 100.00% (30 / 30), significantly higher than that in control group (70.00% (21 / 30), the difference was statistically significant (P < 0.05). Before nursing, there was no significant difference in the scores of physiological function, social function, physical function, overall health, anxiety and depression between the two groups (P > 0.05). After nursing, the scores of physiological function, social function, physical function and overall health of children in the two groups were significantly higher than those before nursing, and the scores of anxiety and depression were significantly lower than those before nursing. The scores of physiological function, social function, physical function and overall health of children in the clinical pathway group were significantly higher than those in the control group, and the scores of anxiety and depression were significantly lower than those in the control group, The difference was statistically significant (P < 0.05). The total diagnosis and treatment time and the improvement time of scarlet fever in clinical pathway group were (8.41 ± 3.12), (3.41 ± 1.34) days, respectively, which were significantly shorter than those in control group (10.41 ± 3.16), (6.24 ± 1.01) days, and the treatment cost (5436.42 ± 1343.22) yuan was significantly lower than those in control group (7636.86 ± 1367.22), with statistical significance (P < 0.05). The incidence of adverse reactions in the clinical pathway group was 3.33% (1 / 30), which was significantly lower than that in the control group (20.00% (6 / 30). The difference was statistically significant (P < 0.05). Conclusion the implementation of clinical nursing pathway for children with scarlet fever can achieve good results, can significantly improve the quality of life of children, reduce anxiety and depression, shorten the treatment time, reduce the cost of treatment, and improve the nursing satisfaction of children's families.
简介:摘要:目的 探讨翻转课堂教学模式在临床护理人员分层级培训中的应用价值。方法 选取 2017年我院 33名 N1层级护士的培训为对照组,采用传统护理培训方法,另选 2018年我院 33名 N1层级护士的培训为观察组,在对照组基础上采取翻转课堂模式进行培训,观察培训开始前、培训结束后两组护理人员的考核成绩及培训质量评价情况。结果 两组护理人员在培训开始前考核成绩差异无统计学意义,培训结束后,观察组理论、操作考核成绩显著高于对照组,差异有统计学意义( P< 0.00 1);观察组培训模式满意、学习积极性 提高、实践 操作能力 增强、解决问题能力 增强 、 自主 学习 能力增强均明显高于对照组,差异有统计学意义( P< 0.05 )。 结论 翻转课堂能显著提高临床护理人员培训质量,提高护理人员学习积极性,值得推广。
简介: 【摘要】 目的 对支气管扩张进行中医治疗的临床疗效的分析。方法 资料选自 2017年 6月—— 2019年 12月在本院诊治的支气管扩张的患者 172例,将患者分为 2组,每组 86例,研究组运用中医方案,对照组运用西医方案,对两组进行临床观察。结果 研究组与对照组比较中,研究组的显效 52例( 60.47%),总有效率为 90.70%;对照组的显效 35例( 40.70%),总有效率为 72.10%。研究组的临床治疗总有效率明显高于对照组,两组的数据相比较有统计学意义( P<0.05)。结论 采用中医治疗支气管扩张,具有治愈率高、方便简单等特点,值得在临床上推广与应用。 【关键词】 中医;支气管扩张;临床;疗效 [Abstract] Objective To analyze the clinical efficacy of traditional Chinese medicine in the treatment of bronchiectasis. Methods 172 patients with bronchiectasis who were treated in our hospital from June 2017 to December 2019 were selected and divided into two groups, 86 cases in each group. The study group was treated with traditional Chinese medicine scheme, and the control group was treated with western medicine scheme. Results compared with the control group, 52 cases (60.47%) were markedly effective in the study group, and the total effective rate was 90.70% in the study group; 35 cases (40.70%) in the control group were markedly effective, and the total effective rate was 72.10%. The total effective rate of the study group was significantly higher than that of the control group, with statistical significance (P < 0.05). Conclusion the treatment of bronchiectasis with traditional Chinese medicine has the characteristics of high cure rate, convenience and simplicity, which is worthy of clinical promotion and application.
简介:摘要:探究肢体语言在儿科护理实践中运用效果。选取91例儿科患儿作为研究对象,采用随机数字表法,将研究对象分为对照组45例,观察组46例。对照组采用常规沟通方式,观察组采用肢体语言沟通,比较两组的护理接受程度、满意度。观察组患儿的护理接受程度显著高于对照组。观察组患儿家属对护理满意度高于对照组(P