简介：Terahertz(THz)radiation,whosefrequencyrangesfrom0.1THzto10.0THz,hasrichscience,butlimitedtechnology.Ithaslongbeenconsideredthelastremainingscientificgapintheelectromagneticspectrum.Farfrombeingfullyexploited,itoffersgreatopportunitiesinscience,innovation,newtechnology,andpotentialapplications.

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简介：基因治疗是为网膜的退化疾病的潜在地有效的治疗。定期聚类interspaced短palindromic重复(CRISPR)/CRISPR-associated蛋白质9(Cas9)系统在眼的研究作为一个新编辑染色体的工具被开发了。在研究的最近的进展证明CRISPR/Cas9在在视网膜炎pigmentosa(RP)和leber的vivo产生动物模型以及基因治疗被使用了先天的黑(LCA)。它被与象联系adeno的病毒(AAV)那样的另外的技术结合也为诊所作为一次潜在的尝试显示出并且导致pluripotent干细胞(iPSCs)。在这评论，我们加亮在指向网膜的退化使用CRISPR/Cas9的进一步的前景的主要的点。我们也在治疗网膜的退化疾病强调这种技术的潜在的应用程序。

简介：ThispaperpresentsdesigntheoryandmethodoftheintellectualizedCAI.whichincludestheorganizationandexpressionoftheteachingcontentandtheteachingrequirementdeterminationinteachingprocess,anddevelopsahighlyintellectualizedCA1software.LA-CAI,touseforlinerarithmeticteachingprogram.

简介：Inthisagecharacterizedbyrapidgrowthinthevolumeofdata,datadeidentificationtechnologieshavebecomecrucialinfacilitatingtheanalysisofsensitiveinformation.Forinstance,healthcareinformationmustbeprocessedthroughdeidentificationproceduresbeforebeingpassedtodataanalysisagenciesinordertopreventanyexposureofpersonaldetailsthatwouldviolateprivacy.Assuch,privacyprotectionissuesassociatedwiththereleaseofdataanddatamininghavebecomeapopularfieldofstudyinthedomainofbigdata.Asastrictandverifiabledefinitionofprivacy,differentialprivacyhasattractednoteworthyattentionandwidespreadresearchinrecentyears.Inthisstudy,weanalyzetheadvantagesofdifferentialprivacyprotectionmechanismsincomparisontotraditionaldeidentificationdataprotectionmethods.Furthermore,weexamineandanalyzethebasictheoriesofdifferentialprivacyandrelevantstudiesregardingdatareleaseanddatamining.

简介：最近，产生在的许多重要非线性的部分微分方程使用了物理、数学的科学被一条流行途径处理了，所谓的终止功能方法。在这份报纸，我们由分析最近的结果的这个方法的现在的一些缺点出版了报纸。我们也讨论方法的有效性的可能的改进。

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简介：Firstly,thispaperreviewsHall'stheoryofbootstrapcriticalpoints(Hall,1988)andtheEdgeworthexpansionforthemetrodirectionσ=μ(Fn)ofdirectionaldata(Wu&Deng,1996),andthenappliesHall'sresultstostudysixbootstrapconfidenceintervalsforcircularmeandirectionμ=μ(F).OurresultsshowthatSTUD-intervalandABC-intervalarebothsecond-ordercorrect.ForyonMisespopudationM(μ,k),wefindthatsixbootstrapconfidenceintervalsaxeseeond-ordercorrectliketheapproximatenormalconfidenceinterval,andSTUD-intervalisthird-ordercorrect.

简介：Withthedevelopmentofwirelessnetworksandmobilecomputing,moreadvancedapplicationswithcontext-awarenessandadaptabilitytotheirchangingcontextareneeded.However,buildingcontext-awareapplicationsisdifficultduetothelackofadequateinfrastructuresupport.Inthispaper,awebmiddlewarearchitectureforthedevelopmentofcontext-awarenessapplicationsusingnearfieldcommunication(NFC)isproposed.Basedonit,theefficientsupportforacquiring,interpreting,andaccessingcontextisprovided,andtheuser’squalityofexperienceisimproved.Moreover,amobilewebmiddlewareforthetestingandfullrealizationofNFCcontext-awarenessapplicationshasbeendevelopedtogetherwithtwoapplicationexamples.

简介：Theproblemofdecisionmakinginanimpreciseenvironmenthasfoundparamountimportanceinrecentyears.Inthispaper,wedefinevaguesoftrelationandsimilaritymeasureofvaguesoftsets.Usingthesedefinitions,somenovelmethodsofobjectrecognitionfromanimprecisemultiobserverdatahasbeenpresented.Moreover,weintroducethenotionofgeneralizedvaguesoftsetsandstudysomeofitsproperties.Thesimilaritymeasureofgeneralizedvaguesoftsetsisalsopresentedandanapplicationofthismeasureindecisionmakingproblemshasbeenshown.

简介：Ageneralversionoftheinvertedexponentialdistributionisintroduced,studiedandanalyzed.ThisgeneralizationdependsonthemethodofMarshall-Olkintoextendafamilyofdistributions.Somestatisticalandreliabilitypropertiesofthisfamilyarestudied.Inaddition,numericalestimationofthemaximumlikelihoodestimate(MLE)parametersarediscussedindetails.Asanapplication,somerealdatasetsareanalyzedanditisobservedthatthepresentedfamilyprovidesabetterfitthansomeotherknowndistributions.

简介：Hybridorganic-inorganicperovskites(e.g.CH3NH3PbI3)haveattractedtremendousattentionduetotheirpromiseforachievingnext-generationcosteffectiveandhighperformanceoptoelectronicdevices.Thesehybridorganic-inorganicperovskitespossessexcellentopticalandelectronicproperties,includingstronglightabsorption,highcarrierabilities,optimizedchargediffusionlengths,andreducedchargerecombinationetc.,leadingtotheirwidespreadapplicationsinadvancedsolarenergytechnologies(e.g.highefficiencyperovskitesolarcells).However,thereisstillalackofinvestigationsregardingfundamentalpropertiessuchasferroelectricityintheseperovskites.Asconventionalferroelectricceramicsarepreparedathightemperatureandhavenomechanicallyflexibility,low-temperatureproceedandflexibleperovskiteferroelectricshavebecomepromisingcandidatesandshouldbeexploitedforfutureflexibleferroelectricapplications.Here,ferroelectricpropertiesinhybridorganic-inorganicperovskitesandseveralstate-of-theartperovskiteferroelectricsarereviewed.Novelferroelectricapplicationsofhybridorganic-inorganicperovskitesarediscussedaswell,providingguidelineforrealizingfuturehighperformanceandflexibleferroelectricdevices.

简介：Thelaser-inducedrelativisticshockwavesaredescribed.Theshockwavescanbecreateddirectlybyahighirradiancelaserorindirectlybyalaseraccelerationofafoilthatcollideswithasecondstaticfoil.Aspecialcaseofinterestisthecreationoflaser-inducedfusionwherethecreatedalphaparticlescreateadetonationwave.Anovelapplicationissuggestedwiththeshockwaveorthedetonationwavetoigniteapre-compressedtarget.Inparticular,thedeuterium–tritiumfusionisconsidered.Itissuggestedthatthecollisionoftwolaseracceleratedfoilsmightserveasanovelrelativisticacceleratorforbulkmaterialcollisions.

简介：Ellipticequationistakenasanansatzandappliedtosolvenonlinearwaveequationsdirectly.Morekindsofsolutionsaredirectlyobtained,suchasrationalsolutions,solitarywavesolutions,periodicwavesolutionsandsoon.Itisshownthatthismethodismorepowerfulingivingmorekindsofsolutions,soitcanbetakenasageneralizedmethod.

简介：InthispaperweestablisharesultaboutuniformlyequivalentnormsandtheconvergenceofbestapproximantpairsontheunitaryballforafamilyofweightedLuxemburgnormswithnormalizedweightfunctionsdependingonε,whenε→0.ItisintroducedageneralconceptofPadeapproximantandwestudyitsrelationwiththebestlocalquasi-rationalapproximant.Wecharacterizethelimitoftheerrorforpolynomialapproximation.WealsoobtainanewconditionoveraweightfunctioninordertoobtaininequalitiesinLpnorm,whichplayanimportantroleinproblemsofweightedbestlocalLpapproximationinseveralvariables.

简介：Single-IonMicrobeam(SIM)isuniquelycapableofpreciselydeliveringapredefinednumberofchargedparticles(precisedosesofradiation)toindividualcellsorsub-cellulartargetsinsitu.Sincetheearly1990's,therehasbeenanever-increasinginterestindevelopingandapplyingtheSIMtechniquetoproblemsinradiobiologyforstudiesofcellandtissuedamagedbyionizingradiations.PotentialapplicationsforSIMinradiobiologycontinuestogrowandhavebeendiversified.Therearecurrentlymorethan14SIMfacilitiesworldwide,andtheyhavebeeninaconstantstateofevolution.ThispaperreviewsthecurrentstateofSIMresearchworldwideandtherelatedpivotaltechnologicaldevelopmentsinthefieldsofbothbiophysicsandradiobiology.RepresentativeapplicationsandtheperspectiveofSIMarealsointroducedanddiscussed.

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简介：Inthefarfieldoftheintensitydistributionofthebeamdeliveredbyatwo-stagetransient–collisionalexcitationX-raylaser(XRL),anon-expectedinterferencepatternthatisstablefromshottoshothasbeendiscovered.Itisdemonstratedthattheinterferenceiscausedbytheemergenceofanimaginarysourceintheamplifyingplasma,whichisphasematchedtotheradiationofthegenerator.TheobservedphenomenoniscalledanX-raycoherentmirage.Toexplaintheobtainedresults,anewtheoreticalapproachisdeveloped.ThebasicessentialconditionsforformationoftheX-raymirageareformulated,andpossibleapplicationsarediscussed.Thispaperdetailstheexperiments,includingtheformulationofthenecessaryandsufficientconditionsforformationoftheX-raymirage,andpossibleapplicationsarediscussed.

简介：Recentadvancesinoptogeneticshaveestablishedapreciselytimedandcell-specificmethodologyforunderstandingthefunctionsofbraincircuitsandthemechanismsunderlyingneuropsychiatricdisor-ders.However,thefabricationofoptrodes,akeyfunctionalelementinoptogenetics,remainsagreatchallenge.Here,wereportreliableandefficientfabricationstrategiesforchronicallyimplantableoptrodearrays.Toimprovetheperformanceofthefabricatedoptrodearrays,surfacesoftherecordingsitesweremodifiedusingoptimizedelectrochemicalprocesses.Wehavealsodemon-stratedthefeasibilityofusingthefabricatedoptrodearraystodetectseizuresinmultiplebrainregionsandinhibitictalpropagationinvivo.Furthermore,theresultsofthehistologystudyimplythattheelectrodepositionofcompositeconductingpolymersnotablyalleviatedtheinflammatoryresponseandimprovedneuronalsurvivalattheimplant/neural-tissueinterface.Insummary,weprovidereliableandefficientstrategiesforthefabricationandmodificationofcustomizedoptrodearraysthatcanfulfilltherequirementsofinvivooptogeneticapplications.