简介:Pulsediagnosisisaspecialmethodofdiagnosingpatient’sdisease.Amathematicalmodelofthepulseispresentedinthispaper.Thefeatureparametersofthesphygmogramareextractedbasedonthesignalmodel.Thediscriminationandprincipalanalysisareemployedtoidentifythepulses.Theresultsarematchingwiththoseoftraditionalmethods.
简介:Theresultsofautomaticclassificationoftheperipheralbloodleukocytecategoriesarepresented.Thisclassificationwasperformedbymeansofdigitalimageprocessingandpatternrecognitiontechniques.Inthispaper,anautomaticmicroscopecellularanalysissystemforthispurposeisgivenandasetofalgorithmsforleukocyterecognitions,whichincludesindividualcell’sdetection,scenesegmentation,featureextraction,selectionandclassifierdesign,isproposed.Asaresultofteston3000leukoeytesdigitizeddirectlyfrom21peripheralbloodsmears,92percentofthemwereclassifiedcorrectlyinthissystem.Thecategorieswerebandneutrophils,seg-mentedneutrophils,monocytes,eosinophils,basophilsandlyrnphoeytes.
简介:BiochaninA(BCA),themostabundantisoflavoneinchickpeas,presentsawiderangeofbiologicalactivities,suchashypolipidaemic,anti-oxidative,antiproliferative,andestrogen-likeeffects.WeinvestigatedtheinteractionbetweenBCAandhumanserumalbumin(HSA)viaseveraltechniques.UV–VisabsorptionspectroscopyverifiedtheconformationalvariationofHSAafterBCAaddition,andfluorescencespectroscopyrevealedtherelevantbindingparameters.CirculardichroismspectroscopywasusedtoestimatethesecondarystructuralchangesofHSAwithandwithoutBCA.MoleculardockinganddynamicssimulationswerethenappliedtostudythecharacteristicsofHSAwithBCA.EnergydecompositionanalysiswasusedtoprovethatTrp214insubdomainIIAofHSAisthemostlikelybindingsiteofBCA.VanderWaalsforcesandhydrophobicinteractionsmayplayimportantrolesduringthebindingprocess.AllofourresultsshowedthatBCApresentssignificantbindingaffinitytoHSA,thusconfirmingthattheroleofHSAhasasanefficienttransporterofbiomolecules.