简介:Inlongtermevolution(LTE)uplinksinglecarrierfrequencydivisionmultipleaccess(SC-FDMA)system,therestrictionthatmultipleresourceblocks(RBs)allocatedtoausershouldbeadjacent,makestheresourceallocationproblemhardtosolve.Moreover,withthepracticalconstraintthatperfectchannelstateinformation(CSI)cannotbeobtainedintime-varyingchannel,theresourceallocationproblemwillbecomemoredifficult.Inthispaper,anefficientresourceallocationalgorithmisproposedinLTEuplinkSC-FDMAsystemwithimperfectCSIassumption.Firstly,theresourceallocationproblemisformulatedasamixedintegerprogrammingproblem.Thenanefficientalgorithmbasedondiscretestochasticoptimizationisproposedtosolvetheproblem.Finally,simulationresultsshowthattheproposedalgorithmhasdesirablesystemperformance.
简介:Thenonlinearbehaviorofacantileveredfluidconveyingpipesubjectedtoprincipalparametricandinternalresonancesisinvestigatedinthispaper.Theflowvelocityisdividedintoconstantandsinusoidaiparts.Thevelocityvalueoftheconstantpartissoadjustedsuchthatthesystemexhibits3:1internalresonancesforthefirsttwomodes.Themethodofmultiplescalesisemployedtoobtaintheresponseofthesystemandasetoffourfirst-ordernonlinearordinary-differentialequationsforgoverningtheamplitudeoftheresponse.TheeigenvaluesoftheJacobianmatrixareusedtoassessthestabilityoftheequilibriumsolutionswithvaryingparameters.Thecodimension2derivedfromthedouble-zeroeigenvaiuesisanalyzedindetail.Theresultsshowthattheresponseamplitudemayundergosaddle-node,pitchfork,Hopf,homoclinicloopandperiod-doublingbifurcationsdependingonthefrequencyandamplitudeofthesinusoidalflow.Whenthefrequencyofthesinusoidalflowequalsexactlyhalfofthefirst-modefrequency,thesystemhasaroutetochaosbyperiod-doublingbifurcationandthenreturnstoaperiodicmotionastheamplitudeofthesinusoidalflowincreases.
简介:前列腺癌症(PCa)是年龄相关的疾病,并且stromal微型环境在prostatic起一个重要作用恶意的前进。然而,在在年轻、旧的织物在场的前列腺stromal房间的差别仍然是阴暗的。我们从改变年龄的施主的正常prostatic外设地区(PZ)建立了主要有教养的stromal房间并且从旧施主发现那有教养的stromal房间(PZ旧)更多被扩大并且比那些多角形从年轻施主(PZ年轻)。基于immunocytochemical和ultrastructural分析,而且,stromal房间的部件与增加施主年龄从成纤维细胞的一个多数改变了到成纤维细胞和myofibroblasts的混合物。用一在vitro文化系统三维,我们发现PZ旧的stromal房间能提高cocultured的增长,迁居和侵略良性的BPH-1和PC-3房间。用一在里面vivo织物再结合系统,我们也发现PZ旧的stromal房间是比在由高经过的BPH-1房间支持瘤形成的PZ年轻的房间更有效的(>;100)并且PC-3房间。到这些的可能的机制完成的探查,我们执行了cDNAmicroarray分析并且在PZ旧的房间介绍了509upregulated基因和188downregulated基因。在改变的基因之中,我们发现了基因为能够影响邻近的上皮的房间的paracrine因素的一个子集编码;这些包括hepatocyte生长因素(HGF),成纤维细胞生长因素5(FGF5),像胰岛素的生长因素2(IGF2),像胰岛素的生长因素绑定蛋白质4(IGFBP4),IGFBP5和矩阵metallopeptidase1(MMP1)。在这些基因的表示的变化被量的即时聚合酶链反应(PCR)进一步证实,西方的弄污和连接酶的immunosorbent试金。总的来说,我们的调查结果显示从旧施主的前列腺PZ的stromal房间是比从在支持邻近的上皮的房间的恶意的过程的年轻施主的类似的房间更活跃的。在为PCa的预防的新潜在的策略的这发现提示。
简介:Asystemofm(≥2)linearconvection-diffusiontwo-pointboundaryvalueproblemsisexamined,wherethediffusiontermineachequationismultipliedbyasmallparameterεandtheequationsarecoupledthroughtheirconvectiveandreactivetermsviamatricesBandArespectively.Thissystemisingeneralsingularlyperturbed.Unlikethecaseofasingleequation,itdoesnotsatisfyaconventionalmaximumprinci-ple.CertainhypothesesareplacedonthecouplingmatricesBandAthatensureexis-tenceanduniquenessofasolutiontothesystemandalsopermitboundarylayersinthecomponentsofthissolutionatonlyoneendpointofthedomain;thesehypothesescanberegardedasastrongformofdiagonaldominanceofB.Thissolutionisdecomposedintoasumofregularandlayercomponents.Boundsareestablishedonthesecompo-nentsandtheirderivativestoshowexplicitlytheirdependenceonthesmallparameterε.Finally,numericalmethodsconsistingofupwindingonpiecewise-uniformShishkinmeshesareprovedtoyieldnumericalsolutionsthatareessentiallyfirst-orderconver-gent,uniformlyinε,tothetruesolutioninthediscretemaximumnorm.NumericalresultsonShishkinmeshesarepresentedtosupportthesetheoreticalbounds.
简介:这个地点和结构的参数无常的动态效果的考虑被标准在大多数国家为核电厂(NPP)要求。抗地震的标准提供二个基本方法分析参数无常。手工地直接处理计算地板反应系列(皇家学会会员)确定的途径珍视是第一个方法。第二个方法是执行概率统计的FRS的分析根据蒙特卡罗方法结果。二个方法能仅仅反映不明确的参数的全面效果,并且结果不能为某个参数影响和贡献被屏蔽。在这研究,基于NPP的地板反应系列的动态分析,为各种各样的不明确的参数的估计的影响的一个全面索引被介绍并且推荐,包括关联系数,回归斜坡系数和旋风秋千。在NPP地震标准补偿指导的缺乏,建议方法能有效地被用来从敏感,尖酸和统计秋千的方面评估各种各样的参数的贡献关联。最后,例子被提供从系统、直觉的观点验证指示物的集合,例如NPP的皇家学会会员的结构参数和贡献的影响的无常。这个索引对参数的不同类型敏感,它为评估为NPP要求的抗地震的参数提供一种新技术。
简介:Thetime-frequencyanalysisofthesignalacquiredbyasingleground-basedmicrophoneshowsatwo-dimensionalinterferencepatterninthetime-frequencyplane,whichiscausedbythetimedelayofthereceivedsignalemittedfromalowflyingaircraftviathedirectpathandtheground-re-flectedpath.Amodelisdevelopedforestimatingthemotionparametersofanaircraftflyingalongastraightlineataconstantheightandwithaconstantspeed.MonteCarlosimulationresultsandex-perimentalresultsarepresentedtovalidatethemodel,andanerroranalysisofthemodelispresentedtoverifytheeffectivenessoftheestimationschemeadvocated.
简介:Thecomplexnatureoflaser-materialinteractioncausesnon-stoichiometricablationofalloysamples.Thisisattributedtomatrixeffect,whichreducesanalyzingcapability.Toaddressthisissue,theanalyticalperformanceofthreedifferentnormalizationmethods,namelynormalizationwithbackground,internalnormalizationandthreepointsmoothingtechniquesatdifferentparametersettingsisstudiedforquantificationofAgandZnbyLaserinducedbreakdownspectroscopy(LIBS).TheLIBSspectraoffiveknownconcentrationofsilverzincbinarycompositeshavebeeninvestigatedatvariouslaserirradiances(LIs).CalibrationcurvesforbothAg(I)line(4d^105s^2S1/2→4d^105p^2P1/2at338.28nm)andZn(I)line(4s5s^3S1→4s4p^3P2at481.053nm)havebeendeterminedatLIof5.86×10^10Wcm^-2.SlopesofthesecalibrationcurvesprovidethevaluationofmatrixeffectintheAg–Zncomposites.Withcarefulsamplepreparationandnormalizationaftersmoothingatoptimumparametersetting(OPS),theminimizationofsamplematrixeffecthasbeensuccessfullyachieved.AgoodlinearityhasbeenobtainedinAgandZncalibrationcurveatOPSwhennormalizedthewholeareaofspectrumaftersmoothingandtheobtainedcoefficientsofdeterminationvalueswereR^2=0.995and0.998closerto1.Theresultsofmatrixeffecthavebeenfurtherverifiedbyanalysisofplasmaparameters.BothplasmaparametersshowednochangewithvaryingconcentrationatOPS.However,athighconcentrationofAg,theobservedsignificantchangesinbothplasmaparametersatcommonparametersettingPS-1andPS-2werethegestureofmatrixeffect.Inourcase,thebetteranalyticalresultswereobtainedatsmoothingfunctionwithoptimizedparametersettingthatindicatesitismoreefficientthannormalizationwithbackgroundandinternalnormalizationmethod.
简介:Thispaperaddressesthefreetransversevibrationsofthinsimplysupportednonhomogeneousisotropicrectangularplatesofbilinearlyvaryingthicknesswithelasticallyrestrainededgesagainstrotation.TheGram-Schmidtprocesshasbeenusedtogeneratetwo-dimensionalboundarycharacteristicorthogonalpolynomials,whichhavebeenusedintheRayleigh-Ritzmethodtostudytheproblem.Thelowestthreefrequencieshavebeencomputedforvariousvaluesofnonhomogeneousparameters,thicknessparameters,aspectratioandflexibilityparameters.Acomparisonoftheresultswiththoseavailableintheliteraturehasbeenmade.Three-dimensionalmodeshapesforthespecifiedplatehavebeenpresented.
简介:Basedonloadseparationtheory,theloadseparationparameterSpbmethodisaneffectiveapproachforestimatingtheJ-resistancecurvefromrecordsofloadversusdisplacementdirectly,usingonesharpcrackedspecimenandanadditionalreferencebluntcrackedspecimen.However,theeffectofthereferencebluntcrackedspecimenonJ-resistancedeterminationwasnotexplicitlyconsideredinpastwork.Inthispaper,amodifiedloadseparationparameterSpbmethodwasdevelopedtoeliminatethiseffect,andthenauniqueestimationofinstantaneouscracklengthforonesharpcrackedspecimencouldbeobtained.Furthermore,aforcedbluntingcalibrationmethodwasalsoadoptedtodeterminetheinstantaneouscracklengthintheloadinseparableregion,referringtoanormalizationmethod.ExperimentsonsteamturbinerotatorsteelCr2Ni2MoVwerecarriedouttoestimateJ-resistancecurvesusinganunloadingcompliancemethod.Byremovingunloadandreloaddatafromload-displacementrecords,theJ-resistancecurveforthesamesharpcrackedspecimenwasestimatedusingthemodifiedseparationparameterSpbmethod.TheresultsindicatethatthemodifiedSpbmethodcompletelyeliminatestheeffectofthereferencebluntcrackedspecimenontheinstantaneouscracklengthdeterminationofthesharpcrackedspecimen.However,differentJ-resistancecurvesinasmallrangeofcrackextensionarepresentwhendifferentbluntingcoefficientsareusedinthebluntinglineequation.TheJ-resistancecurveobtainedfromthemodifiedSpbmethodagreeswellwiththatobtainedfromthecompliancemethod.
简介:Toconsidertheanisotropicdamageinfatigue,animprovedboom-panelmodelispresentedtosimulatearepresentativevolumeelement(RVE)intheframeworkofcontinuumdamagemechanics.TheanisotropicdamagestateoftheRVEisdescribedbythecontinuityextentsofboomsandpanels,whosedamageevolutionsareassumedtobeisotropic.Thenumericalimplementationisproposedonthebasisofdamagemechanicsandthefiniteelementmethod.Finally,theapproachisappliedtothefatiguelifepredictionof2A12-T4aluminiumalloyspecimenundercyclicloadingoftension-torsion.Theresultsindicateagoodagreementwiththeexperimentaldata.