简介:BackgroundRightbundlebranchblock(RBBB)maypresentasslurredornotchedSwaveinleadV1.However,slurredornotchedSwavemayalsorepresentslowconductioninthemyocardium.MethodsWeretrospectivelyanalyzedtheQRSpatternsinleadsV3RtoV5Rin7patientswithaslurredornotchedSwaveinleadV1.ResultsIntheleadsV3RtoV5R,6patientsshowedincompleteorcompleteRBBBand1patientslurredornotchedSwave.ConclusionsInthemajorityofECGsinasmallpatientserieswithslurredornotchedSwaveinleadV1,QRSmorphologyindicatingincompleteorcompleteRBBBwaspresentinleadsV3RtoV5R.AfindingoffragmentedQRSintheseleadsmayindicateslowconductioninthemyocardium.
简介:APeruviannative,Dr.VelardeearnedhermedicaldegreefromtheNewYorkUniversitySchoolofMedicineinNewYorkandwentontocompleteherresidencytraininginInternalMedicineatColumbiaPresbyterianMedicalCenterandCardiovascularDiseasefellowshiptrainingatMountSinaiHospitalinNewYorkandBostonUniversity.Dr.GladysP.VelardeisAssociateProfessorofMedicine/CardiologyatTheUniversityofFlorida,JacksonvillewhereshedirectstheWomen’sCardiovascularHealthProgramandisDirectoroftheCardiovascularDiseaseFellowshiptrainingprogram.
简介:波士顿科学国际有限公司是一家全球性的医疗技术产品研发、生产、营销公司,现有17,500名雇员,2005年的销售收入为63亿美金。在过去的二十五年中,公司为广泛的医疗技术领域提供了具有深度和广度的众多创新产品,从而推动了微创介入产品的实践和发展。通过提供传统外科手术的替代产品,波士顿科学公司致力于帮助医生和其它医疗行业工作者改善病人的生命质量。
简介:StandardTherapyforHeartFailureUntilnowtheprincipalfocusofheartfailuretherapyhasbeenonthesympatheticnervoussystemandtherenin-angiotensinsystem.Betablockadecounterstheunwantedeffectsofcatecholaminesonthemyocardiumaswellasmoderatelyreducingafterload.Sinceangiotensinisavasoconstrictorandhassometoxiceffectonthemyocardium,bothcontributingtoheartfailure,inhibitionoftherenin–angiotensinsystemhasbeenlogicaltherapyforheartfailure.However,useofangiotensinconvertingenzyme(ACE)inhibitorsmayincreasebradykininlevels,whichareresponsibleforthecoughthatmaybeassociatedwiththeiruseaswellasangioedemathatmayresultfromthesamemedications.
简介:The5thChina-JapanJointHypertensionSymposiumwasheldonNovember6th,2002inGuangdongCardiovascularInstitute,GuangdongProvincialPeople’sHospital,Guangzhou,China.Therewereatotalof96paperspublished(includedspeciallectures,oralpresentations,posters).Almost200cardiologists,whocamefromJapanandChina,attendedthesymposium.
简介:The5thAnnualScientificSessionofCardiologyinSouthChinawasheldfromApril3—7.2003inGuangzhou.Aseminar——“TheFrontlineProblemsandNewViewpointsinCardiologyinRecentTimes”washeldatthesametime.MorethanonethousandcardiologyspecialistscamefromsouthandmiddleChinatoparticipateinthemeetingand135paperswere
简介:ObjectivesPhenotypicoverlapofBrugadasyndromewithtype3longQTsyndromeisobservedinsomecarriersofmutationsintheNachannelSCN5A.Concomitant-Brugadasyndromeand3typelongQTsyndromeassociatedwithsodiumchannelmutationwasreportedbefore,however,nodatashowedconcomitant-BrugadatypeandshortQTintervalelectrocardiogram(ECG)andrevealedtheassociated-genemutation.MethodsThedirectDNAsequencewasconducedtofindthemutation.Themutationwasreproducedinvitrousingsite-directedmutagenesisandcharacterizedusingthepatchclamptechniqueinthewhole-cellconfiguration.ResultsThepatientwiththefamilyhistoryofsuddendeathshowedBrugadaandshortQTintervalECG.SequenceofSCN5Aidentifiedamissensemutation,R689H,previouslyassociatedwithalongQTsyndrome.BiophysicalstudyshowedthattheR689Hfailedtogenerateanycurrentwhenheterolo-gouslyexpressedinHEKcells.ConclusionsOurfindingsindicateforthefirsttimethatcoexisted-BrugadatypeandshortQTintervalECGlinkedtothelossoffunctioninSCN5Amutation.
简介:患者女性,64岁,因活动后心慌。心前区不适3年.加重伴心前区疼痛1天就诊。查体:患者痛苦面容.皮肤湿冷;体温35.50℃;心率160次/分;呼吸28次/分;血压80/60mmHg。立即检查心电图示房室折返性心动过速。随即在心电监测下做左侧颈脉窦按摩,按摩约3s后,即出现1.34s的窦性停搏,又在一次P—R间期缩短的室上性激动后出现-12.38s的窦性停搏.当停搏8.86s时,患者出现两眼上翻,面色苍白.肌张力增强,立即心前区叩击一次并胸外心脏按压,3.5s后相继出现2.4s的室性心动过速,6s的室性自主心律,频率为27次/分的窦性心动过缓,以及3~6s的窦性停搏,持续心脏按压.吸氧约2min后.患者意识恢复,心电图转为窦性心律,呈窦性心动过缓.LGL预激综合症,缺血性ST段压低,继续观察心电图变化,可见ST段压低有所缓解,遂送入病房,给予抗凝。抗血小板凝集,J3受体阻滞剂等治疗,7天后临床治愈出院。
简介:The5thSCCSS&IICwillbeheldonApril4th-7th,2003intheGuangdongHotel,GuangzhouCity,About800specialistsandclinicalphysiciansincardiologywillattendtheconlerences.TheywillcomefromGuandong.Hunan,Hainanandotherprovincesinmedial-southChina.ManyworldfamouscardiologistsfromAmerica,Canada,Germany,theU.K.andHongkong,Beijing,Shanghai,etc.,willbe
简介:BackgroundApolipoprotein(apo)A-Visanovelmemberoftheapolipoproteinclusterinvolvedintriacylglycerol(TG)homeostasis.IthasreportedthatAPOA5genepolymorphismsiscorrelatedwitharterioscleroticdiseases.However,ThisassociationisunknownonChinesepatientswithatheroscleroticcerebralinfarction.ThepresentstudyaimedtoelucidatetherelationshipofAPOA5-1131T>Candarterioscleroticcerebralinfarction(ACI)aswellasthelevelsofserumlipids.MethodsPolymerasechainreaction-restrictionfragmentslengthpolymorphisms(PCR-RFLP)analysis,enzymaticandimmunoturbidimetrymethodswereusedtomeasure-1131T>Cgenotype,allelefrequencyaswellasplasmalipidlevelof90ACIpatientsand221healthysubjectsofHanChinese.ResultsInACIgroup,thelevelofTGinalleleCcarrierswashigherthanthatofnon-Ccarriers(P<0.05).ThefrequencyofalleleCinACIgroupwashigherthaninhealthygroup(χ~2=5.568,P=0.018).Exceptsex,ageandBMI,thelevelsoftotalcholesterol(TC),triglycerides(TG),highdensitylipoproteincholesterol(HDL-C),low-densitylipoproteincholesterol(LDL-C),APOA1andAPOBinACIgroupdistinctivelywerehigherthanthoseinhealthygroup.ConclusionTheAPOA5-1131alleleCisassociatedwiththehighlevelofTGinACIpatients,whichisprobablylinkedwithACIdangerofChineseHan.