学科分类
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1 个结果
  • 简介:Objective:Tostudythemechanismofelectroacupuncture(EA)ofscalp-pointsforregulatingabnormaldischargesofneuronsindifferentregionsaroundthecerebralhemorrhagefocusbyusingneuro-electrophysiologicalmethods.Methods:80Wistarrats(anesthetizedwith20%urethane1g/kg,I.p.)wererandomlydividedintonormal,saline,modelandEAgroups,with20casesineachgroup.Cerebralhemorrhagemodelwasestablishedbyintracerebralinjectionoftherat'sownarterialbloodsample(40uL).Inratsofsalinegroup,thesamevolumeofsalinewasgivenforintracerebralinjection.ExtracellularelectricalactivityofneuronsofthecaudatenucleusandparafascicularnucleusandTailfiliformneedlesandstimulatedelectricallywithstimulatingparametersofstrengthof1V,frequencyof15Hzanddurationof15min.Results:Comparedwithnormalgroup,TFLvaluesofmodelgroupandEAgroupincreasedsignificantly(P<0.01);andcomparedwithmodelgroup,thoseofEAgroupdecreasedsignificantly(P<0.01),suggestingthatthepainthresholdincreasedsignificantlyincerebralhemorrhageratswhileafteracupuncturestimulation,itloweredstrikingly.Comparedwithnormalandsalinegroups,thelatencyvaluesofthepainexcitementandinhibitoryresponsesofthecellulardischargesofthecaudateandparafascicularnucleiinmodelandEAgroupsincreasedsignificantly(P<0.05~0.01),whileafterEA,itrecoveredapparently(P<0.01),showinganapparentregulativeeffectofEAontheabnormalchangesofdischargesofneuronsaroundthecerebralhemorrhagefocus.Conclusion:Scalp-acupuncturepossessesanapparentregulatoryeffectontheabnormalelectricalactivityofneuronsaroundthecerebralhemorrhagefocuswhichmayfavortheearlyrecoveryoffunctionalactivityofneuronsnearthefocustissues.

  • 标签: 电针刺 头皮点 变态发射 神经病理学 中医药疗法 急性大脑出血