简介:AHFreceiverfordatatransmissionbasedonKalmanfilterandchannelestimatorisproposed.Thesimulationresultsshowthattheperformanceoftheproposedschemeisabout2dBbetterthanthatofDecision-FeedbackEqualizerbasedonSquare-RootKalmanAlgorithm(SRKA/DFE)anditscomputationalcomplexityislowerthanthatofMaximumLikelihoodSequenceEstimation(MLSE).
简介:TheRamanspectrafromleukemiccellline(HL60)andnormalhumanperipheralbloodmononuclearceils(PBMCs)areobtainedbyconfocalmicro-Ramanspectroscopyusingnear-infraredlaser(785nm)excitation.Thescanningrangeisfrom500to2000cm-1.ThetwoaverageRamanspectraofnormalPBMCsandcarcinomacellshavecleardifferencesbecausetheirstructureandamountofnucleicacid,protein,andothermajormoleculesarechanged.Thespectraarealsocomparedandanalyzedbyprincipalcomponentanalysis(PCA)todemonstratethetwodistinctclustersofnormalandtransformedcells.Thesensitivityofthistechniqueforidentifyingtransformedcellsis100%.更多还原
简介:Solidificationstructurevariationofsinglephasealloywithundercoolingpriortonucleationhasbeenwidelystudied.Theprogress,especiallyduringthelastdecade,isreviewedsoastogiveacomprehensiveknowledgeforit,inwhichtheemphasesarelaidonthestructureevolutionmechanismandthepotentialapplication.Lastly,thefutureinterestingsubjectsarepresented.
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简介:ImmunizationwithinactivatedautoreactiveTcells(Tcellvaccination)selectedfromindividual'sownTcellrepertoireprovidesauniqueinvivosettingfortestingimmuneregulationthatisknowntoinvolveinteractionsofavarietyofrelatedsurfacemolecules(1).ItinducesregulatoryimmuneresponsesthatcloselyresembletheinvivosituationwheretheimmunesystemischallengedbyclonalactivationandexpansionofgivenTcellpopulationsinvariousautoimmunediseases.TcellvaccinationprovidesapowerfulmeansofelicitingnaturalreactionsoftheimmunesysteminresponsetoclonalexpansionofTcells,whichcanusedasatherapeuticapproachtosuppressoreliminatespecificpathogenicautoreactiveTcellsinautoimmuneconditions.ClinicaltrialsusingTcellvaccinationtodepleteautoreactiveTcellsinhumanautoimmuneconditionshavebeguntorevealthepathologicrelevanceofvariousautoimmuneTcellpopulationsinthediseaseprocesses,providingauniqueopportunitytotesttheautoimmunetheoriesinaclinicalsetting.Cellular&MolecularImmunology.2004;1(5):321-327.
简介:Basedonfractalsuperfibersandbinaryfractalfibers,thefollowingobjectivesareapproachedinthispaper:First,theconceptofmultiple-cellelementsisinducedandabstracted.Second,throughmultiple-cellelements,theconstructabilityofregularmultifractalswithstrictself-similaritiesisconfirmed,andtheuniversalityoftheconstructionmodeforregularmultifractalsisproved.Third,throughtheconstructionmodeandmultiple-cellelements,regularmultifractalsaredemonstratedtobeequivalenttogeneralizedregularsinglefractalswithmultilayerfinestructures.Onthebasisofsuchequivalence,thedimensionformulaoftheregularsinglefractalisextendedtothatoftheregularmultifractal,andthegeometryofregularsinglefractalsisextendedtothatofregularmultifractals.Fourth,throughregularmultifractals,afewgoldenfractalsareconstructed.
简介:Inthepresentstudythemembranefoulinginmicrofiltrationusedforcellharvestinginadeadendsystemhasbeeninvestigated.experimentalresultswereanalysedintermsofexitingmembranefiltrationmodelsandmembraneresistances.Thecakefiltrationmodel(CFM)andstandardblockingmodel(SBM)havebeenconsideredinthisstudy.Variousmembraneresistancesweredeterminedatdifferentprocessingtime,feedconcentrationandstirringspeed.Resistancestopermeationinthissystemincludefiltermedium,poreblocking,adsorption,cakelayerandconcentrationpolarization.
简介:Thispaperpresentsafunctionallanguagefortheunambiguousdescriptionofdigitalcircuits,amethodandalgorithmstoobtainastandard-celllayout,andacomparativeevaluationofthedevelopedfunctionalstandard-cellplacementtechnique.Thepresentedplacementschemeisdifferentfromtraditionalmethodsbecausethecompletelayoutgrometryisspecifiedandconstructedautomaticallyfromafunctionaldescription.Theconstructionreliesonatranslationthatcombinesthesimplicityofstandard-cellswiththeeleganceoffunctionalprogramming.Anevaluationofthemethodintroducedshowsthatthequalityoftheresultingplacementisclosetotheresultsachievedwithsimulatedannealingwhilethecomputationtimeissignificantlyless.Furthermore,theevaluationsuggeststoemploythefunctionalplacementmethodinconjunctionwithlow-temperaturesimulatedannealingforrunning-timereductionandimprovedresults.
简介:Traditionally,thematerialswhichareregardedasantigensrecognizedbyγδTlymphocytesareproteinandcarbohydrate,notnucleicacidorlipid.Recently,ithasbeendemonstratedthatγδTcellscanrecognizelipidAanddirectlyinduceimmuneresponsesthatinvolveCD1(clusterofdifferentiationtype1)familyandTolllikereceptors(TLRs).Thisisareviewabouttheinteracting-mechanism,immunologicaleffectandclinicalapplicationofthem.Cellular&MolecularImmunology.
简介:Programmedcelldeathplaysanimportantroleinmaintaininghomeostasisduringanimaldevelopment,andhasbeenconservedinanimalsasdifferentasnematoesandhumans.RecentstudiesofDrosophilahaveprovidedvaluadleinformationtowardourunderstandingofgeneticregulationofdeath.Differentsignalstriggerthenoveldeathregulatorsrpr,hid,andgrim,thatutilizetheevolutionarilyconservediapandarkgenestomodulatecaspasefunction.Subsequentremovalofdyingcellsalsoappearstobeaccomplishedbyconservedmechanisms.ThesimilaritybetweenDrosophilaandhumanincelldeathsignalingpathwaysillustratethepromiseoffruitfliesasamodelsystemtoelucidatekthemechanismsunderlyingregulationofprogrammedcelldeath.