简介:摘要目的比较三种不同免疫抑制剂联合糖皮质激素治疗IgA肾病的效果。方法回顾性分析濮阳市安阳地区医院2018年4月至2021年4月收治的148例IgA肾病患者的临床资料,患者均采用糖皮质激素治疗,依据联用的免疫抑制剂,分别将联用雷公藤多苷(TW)、来氟米特(LEF)、环磷酰胺(CTX)的患者纳入TW组(48例)、LEF组(46例)和CTX组(54例)。比较三组患者的疗效、不良反应发生率及治疗前后肾功能指标、血清指标[单核细胞趋化蛋白-1(MCP-1)、细胞间黏附分子-1(ICAM-1)以及转化生长因子-β1(TGF-β1)]水平。结果TW组(95.83%,46/48)与LEF组(93.48%,43/46)治疗总有效率均高于CTX组(75.93%,41/54),P均<0.05;而TW组与LEF组治疗总有效率比较差异未见统计学意义(P>0.05)。治疗后,三组肾功能指标均低于治疗前(P均<0.05),且TW组与LEF组肾功能指标低于CTX组(P<0.05),TW组与LEF组比较差异未见统计学意义(P>0.05)。治疗后,三组MCP-1、ICAM-1、TGF-β1水平均低于治疗前(P均<0.05),且TW组与LEF组MCP-1、ICAM-1、TGF-β水平低于CTX组(P<0.05),TW组与LEF组上述血清指标比较差异未见统计学意义(P>0.05)。TW组(6.25%,3/48)与LEF组(8.33%,4/46 )不良反应发生率低于CTX组(27.78%,15/54),P<0.05;TW组与LEF组不良反应发生率比较差异未见统计学意义(P>0.05)。结论糖皮质激素联合TW与LEF治疗IgA肾病的疗效相当,且均优于糖皮质激素联合CTX。
简介:摘要:核心素养在小学体育教学中的应用能够有助于小学生综合素质的提升。文章对体育核心素养进行分析,探讨小学体育教学现状,并对核心素养下小学体育教学工作提出一些建议。
简介:摘要:英语学习的过程也是习惯养成的过程。良好的英语学习习惯不会自然生成的,而是经有意识培养形成的。我认为,让学生养成良好的英语学习习惯,对他们听,说,读,写等各方面能力的培养尤为重要。因此,我们要注意在日常教学活动中有计划地、有步骤、严格地训练学生。
简介: 摘要:目的 探讨整体护理在老年上消化道出血患者中应用效果观察。方法 选取我科 2018年 12月~ 2019年 6月共收治 40例老年上消化道出血患者为对照研究,采取常规护理与整体护理,对比两组前后护理总有效率。结果 观察组患者护理总有效率为( 95%)明显优于对照组患者护理总有效率( 85%);观察组患者的生存质量明显高于对照组,两组对比差异有统计学意义( P<0.05)。结论 将整体护理措施纳入老年上消化道出血临床治疗中,有效改善临床治疗成效,降低并发症的发生,使患者获得了康复。 关键词:整体护理;老年上消化道出血;效果观察 Abstract: Objective To explore the effect of holistic nursing in elderly patients with upper gastrointestinal hemorrhage. Methods a total of 40 elderly patients with upper gastrointestinal bleeding were enrolled in our department from December 2018 to June 2019 as control study. Routine nursing and holistic nursing were adopted to compare the total effective rate of nursing before and after the two groups. Results the total effective rate of nursing in the observation group (95%) was significantly higher than that in the control group (85%); the quality of life in the observation group was significantly higher than that in the control group (P < 0.05). Conclusion the whole nursing measures should be included in the clinical treatment of upper gastrointestinal hemorrhage in the elderly, which can effectively improve the clinical treatment effect, reduce the occurrence of complications, and make the patients recover.
简介: 【摘要】目的:对急性胃炎患者行综合性护理的临床护理效果进行研究分析。方法:选取 62例急性胃炎患者随机分为两组(各 31例),一组为综合性护理组,一组为常规护理组。结果:综合性护理组患者实施临床护理治疗后总有效率显著高于常规护理组患者( 93.55%和 70.97%),差异有显著性( P<0.05)。结论:在对急性胃炎患者护理时综合性护理措施效果较为理想。 【关键词】急性胃炎患者;综合性护理;临床护理效果 [Abstract] Objective: To study and analyze the clinical nursing effect of comprehensive nursing for patients with acute gastritis. Methods: 62 patients with acute gastritis were randomly divided into two groups (31 cases in each group). One group was comprehensive nursing group, the other was routine nursing group. Results: the total effective rate of the comprehensive nursing group was significantly higher than that of the conventional nursing group (93.55% and 70.97%), and the difference was significant (P<0.05). Conclusion: the effect of comprehensive nursing measures is ideal in the nursing of patients with acute gastritis.