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  • 简介:Theassessmentofthewave-inducedsoilliquefactionplaysakeyroleinthegeotechnicaldesignforoffshorefoundations.Theunderlyingshortcomingsoftheexistingmomentaryliquefactioncriteriaareidentifiedandclarifiedbymechanismanalysesandtherecentfieldobservations.Amodifiedcriterionforthewave-inducedmomentaryliquefactionofasandyseabedisgiventodescribetheverticalporepressuredistributions.Animprovedapproximationofthemomentaryliquefactiondepthisfurtherpresented.Parametricstudyoftheeffectsofthesaturationdegreeofsoilsindicatesthatthismodificationissignificantfortheevaluationofwave-inducedmomentaryliquefaction.

  • 标签: 土壤液化 沙质海床 标准 瞬间 波浪 压力分布
  • 简介:瞄准:在老鼠把芙蓉sabdariffa(Roselle)和姜officinale(生姜)的保护的效果与导致cisplatin的繁殖毒性作比较并且学习位于这些效果下面的机制。方法:H.sabdariffa或Z.officinale(1g/kgx天)的乙醇摘录被给p.o到男白鼠26天,它在单个cisplatini.p注射(10mg/kg体重)前开始了21天。结果:H.sabdariffa和Z.officinale的摘录减少了导致cisplatin的精子反常的程度并且提高了精子活动性。两篇摘录恢复了malondialdehyde(MDA)的控制水平(类脂化合物每氧化标记)在对待cisplatin的睾丸。导致的cisplatin注射在超级氧化物的层次衰退歧化酶(草皮),减少的谷胱甘肽(GSH)和过氧化氢酶(猫)显著地被颠倒在cisplatin被H.sabdariffa或Z.officinale的管理先于的组控制层次。结论:H.sabdariffa和Z.officinale处理增加了阴囊的抗氧化剂酶的活动并且恢复了对待cisplatin的老鼠的精子活动性。因此,测试植物的保护的效果被建议被他们的有势力抗氧化剂活动调停。

  • 标签: 玫瑰茄 生姜 毒性 实验研究
  • 简介:Inthispaper,laserinducedplasmasignalswereanalyzedduringkeyholeweldingthroughthreemethods.Accordingtotheresults,therelativitybetweenopticalandacousticsignalsofplasmaisshownwhenweldsareinfull-penetration,orpartial-penetrationandnon-penetration.

  • 标签: 激光焊接 等离子体 光学信号 声学信号
  • 简介:Thisstudydemonstratesanovelapproachforrapidsynthesisofsilver(Ag)nanowiresinducedbyvanadiumtrioxide(V2O3)particlesinaqueoussolutionatroomtemperature.Silvernanowireshaveanaveragediameterof20nmandlengthuptoafewmicrometersbyparametricoptimization.ThemicrostructureofthesilvernanowireswascharacterizedbyTEM,HRTEM,SEM,andXRDtechniques.Theopticalpropertyoftheas-preparedproductwasmeasuredbyultraviolet-visible(UV-vis)spectroscopy.ThepossiblegrowthmechanismofAgnanowiresviaorientedattachmentofAgnanocrystalswasdiscussed.Thepresentapproachshowsseveraluniquefeaturessuchasrapid(afewminutes),reproducibleandhigh-yieldreactionwithnoneedofanymodifiers.V2O3rodswerereportedforthefirsttimetobeusedforsynthesisofsilvernanowires,playingmultiplerolesasreducingagent,template,andcatalyst.Thesilvernanowiresproducedarepromisingforopticalapplications(e.g.,SERS)duetotheirroughsurface.

  • 标签: 银纳米线 快速合成 生长机制 三氧化二钒 高分辨透射电子显微镜 诱导
  • 简介:Thispaperintroducesthebasickineticandthermodynamicfactorsaffectingstep-bunchinginstabilityandderivetheone-dimensional(1D)stepmotionequationbasedadatomdiffusionequationforfurtheranalysis.Thestep-bunchinginstabilityisanalyzedfordifferentcases.

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  • 作者: Yang Guang Fang Jugao Shi Qiang Wang Ru Lian Meng Ma Hongzhi Feng Ling Shen Xixi Wang Yu
  • 学科: 医药卫生 >
  • 创建时间:2020-08-10
  • 出处:《世界耳鼻咽喉头颈外科杂志英文版》 2020年第01期
  • 机构:Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical Universit, Beijing, 100730, China; Department of Otorhinolaryngology Head and Neck Surgery, Former 263 ClinicalCenter of People’s Liberation ArmyGeneral Hospital, Beijing Key Laboratory of Head and Neck Molecular Diagnostic Pathology, Beijing, 100730, China,Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical Universit, Beijing, 100730, China; Key Laboratory of OtOlaryngology Head and Neck Surgery(Captical Medical University), Ministry of Education, Beijing, 100730, China,Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical Universit, Beijing, 100730, China,Department of Otorhinolaryngology Head and Neck Surgery, Former 263 ClinicalCenter of People’s Liberation ArmyGeneral Hospital, Beijing Key Laboratory of Head and Neck Molecular Diagnostic Pathology, Beijing, 100730, China
  • 简介:AbstractObjective:To investigate the expressions of MAPK10, c-Jun and Itga6 in laryngeal carcinoma and its influence on the sensitivity to docetaxel, cisplatin and 5-fluorouracil (TPF) chemotherapy.Methods:Fifty-seven patients with supraglottic squamous cell carcinoma, who were treated by two cycles of TPF induction chemotherapy in our hospital, were enrolled in this study and divided into groups by chemotherapy resistance or chemotherapy sensitivity. The expressions of mRNA and protein of MAPK10, c-Jun and Itga6 in tumor tissues were evaluated by immunohistochemistry. The consistency of mRNA and protein expressions was tested, and the relation with the clinicopathological features was analyzed.Results:The positive rates of MAPK10 andc-Jun in the tumor tissues of the sensitive group were significantly higher than those of there assistant group, which was 90.48% and 100.00%, respectively. The expression rate of Itga6 was significantly higher in the resistant group, which was 83.33% (P < 0.05). The mRNA levels of MAPK10 and c-Jun were significantly lower in the resistant group than in the sensitive group, whilethemRNA levelof Itga6was significantly higher in the resistant group (P < 0.05). The protein expressions of MAPK10, c-Jun and Itga6 were consistent with their mRNA expressions (P < 0.05). The expressions of MAPK10, c-Jun and Itga6 were not correlatedwithage, gender and tumor diameter (P > 0.05). However, the expressions of MAPK10 and c-Jun were negatively correlated withclinical stage and pathological grading (P < 0.05). Negative correlations between MAPK 10 and Itga6, and between c-Jun and Itga6in tumor tissues were found by Spearman’srank correlation coefficient (P < 0.05). The correlation was also negative in the resistant tumor tissues (P < 0.05).Conclusion:The MAPK10 and c-Jun expressions were down-regulated, while the Itga6 expression was up-regulated in the chemo-resistant laryngeal carcinoma, and the expression levels of different factors were correlated witheach other. These factorsmight be important biomarkers for predicting outcomes of TPF chemotherapy in laryngeal carcinoma in the future.

  • 标签: Larynx carcinoma Drug resistance MAPK10 c-Jun Itga6
  • 简介:AtheoreticalinvestigationonthepH-inducedswitchingofmixedpolyelectrolytebrusheswasperformedbyusingamoleculartheory.TheresultsindicatethattheswitchingpropertiesofmixedpolyelectrolytebrushesaredependentonthepHvalues.AtlowpH,negativelychargedchainsadoptacompactconformationonthebottomofthebrushwhilepositivelychargedchainsarehighlystretchedawayfromthesurface.AthighpHvalues,theinversetransformationtakesplace.TheroleofpHdeterminingthepolymerchainsconformationandchargebehaviorofmixedpolyelectrolytebrusheswasanalyzed.Itisfoundthatthereexistsamechanismforreducingstrongelectrostaticrepulsions:stretchingofthechains.TheH+andOH-unitsplayamoreimportantroleascounterionsofthechargedpolymersdo.ThecollapseofthepolyelectrolytechainsfordifferentpHvaluescouldbeattributedtothescreeningoftheelectrostaticinteractionsandthecounterion-mediatedattractiveinteractionalongthechains.

  • 标签: 高PH值 聚电解质 开关特性 混合电解质 复合 静电相互作用
  • 简介:现在的工作被奉献给在冻结的magnetar赋予以对一个电场直角的一个极端强壮的磁场的外壳中演变的波色子的学习,两个都由周期的功能描述了。我们沿着盎士通过一个维的潜在的障碍讨论量通道过程。KleinGordon方程的答案以Mathieu为可计算出来的粒子的精力范围,正在转弯从的功能被表示对指数地沿着盎士种模式摆动。在JeffreysWentzelKramersBrillouin框架以内,传播系数在不稳定性范围的中间为粒子动量被计算。

  • 标签: 超强磁场 玻色子 地壳 磁星 相对论 隧道
  • 简介:Helixunwindinginferroelectricliquidcrystalsinducedbyanelectricfieldistheoreticallystudiedonthebasisofthecontinuumtheory.Byapplyingaweakelectricfieldtiltedtothesmecticlayers,thecontributionofthedielectricinteractionenergydensitytothetotalfreeenergydensityisincreased.Approximationmethodsareusedtocalculatethefreeenergyfordifferenttiltanglesbetweentheelectricfieldandthesmecticlayers.Theobtainedresultssuggestselectingtheoptimalnumberofpitchesinthefilmthatmatchestotheminimumofthefreeenergy.

  • 标签: 电场诱导 铁电液晶 螺旋 连续介质理论 自由能密度 能量密度
  • 简介:Theproblemoficeinducedvibrationiscommontooceanengineeringofcoldregioncountries.Tostudytheiceinducedvibrationofacompliantconicalstructure,aseriesofmodeltestshavebeenperformedandsomebreakthroughprogressesmade.Theicesheetbeforethecompliantconicalstructureisfoundtofailbytwo-timebreakinginthetests.Theprocessoftwo-timebreakingbehavesintwomodes,andthegeneralcontroloftheiceandstructuralconditionsdeterminethemodeinwhichtheiceforcewouldbehave.Twodynamiciceforcefunctionsareestablishedrespectivelyforthetwomodesoftwo-timebreakingprocessinthispaper.Thenumericalsimulationresultsareingoodagreementwiththemeasuredresults,indicatingthatthedynamiciceforcefunctionsgiveninthispapercanfullyreflecttherealsituationofthedynamiciceforceonacompliantconicalstructure.

  • 标签: 可靠性分析 海冰 模糊学 圆锥结构 海洋水文
  • 简介:The45°scatteringofafemtosecond(60fs)intenselaserpulsewitha20nmFWHM(thefullwidthathalfmaximum)spectrumcenteredat790nmhasbeenstudiedexperimentallywhilefocusedinargonclustersatintensity~1016W/cra2.Scatteringspectraunderdifferentbackingpressuresandlaser-plasmainteractionlengthswereobtained,whichshowedspectralblueshifting,beamrefractionandcomplexmodulation.Theseionization-inducedeffectsrevealthemodulationoflaserpulsespropagatinginplasmasandtheexistingobstacleinlaserclusterinteractionathighlaserintensityandhighelectrondensity.

  • 标签: 丛聚等离子体 费秒激光脉冲 离子化 人工散射 加热方式
  • 简介:现在的学习是为检测HIFU调查微分成像方法(高紧张集中了超声)导致的损害和为有木头的损害评估的变细的变化的评价光谱差别算法。在vitro的牛的肌肉和肝的实验结果被获得。为损害察觉的几个算法-绝对差别(广告),加绝对差别(悲伤)并且加摆平的差别(SSD)-与几种窗户尺寸和阀值价值被分析。当时,三个变细参数与相比评估织物的度损坏。它被发现吝啬的变细的那个变化()是一个有效参数评估损害。

  • 标签: 超声成像 诱导损害 高强度聚焦超声 评价
  • 简介:TheeffectofreflectionontheperformanceofAM-VSBCATVlightwavesystemsisanalyzed.Usually,therearethreekindsofreflectionexistingintheAM-VSBCATVlightwavesystems:multipathinterference(MPI),doubleRayleighbackscattering(DRB)andexternalopticalfeedbackTheMPIandexternalopticalfeedbackcanbeneglectedowingtousingtheFC/APCconnectorsandisolatedDFBalsersinthesystemlink.ItisshowntheoreticallyandexperimentallythattheDRBisthelimitationofthenoiseinducedbyreflection.

  • 标签: 有线电视 光波系统 双瑞利反向散射 AM-VSB
  • 简介:在长期的rheological砍有半固体合金的实验,粒子变粗将窜改试验性的结果的解释。变粗被shear加强导致的传送对流和粒子的吝啬的尺寸在实验期间显著地被改变。一个简单模型被建立了它考虑传送对流的影响。产生生长法律被简化了因为散开和传送对流统治了生长。生长法律被验证与砍在有A356和听铅合金的一个Searl电流计的实验。实验证明在传送对流下面,生长跟随一条线性时间法律并且率常数取决于shear率的根。试验性的结果的修正被表明获得真粘性功能为一shear跳有A356的实验。

  • 标签: 剪切试验 半固态合金 颗粒粗化 诱导 A356合金 实验过程