简介：【摘要】知识经济时代教育目标之一，是培养具有STEM素养的人才，并称其为全球竞争力的关键。基于我校信息技术示范校和我区在全国内信息技术示范点的前提下和我们学校信息处团队课题研究指导带领下，我们的学校在STEM教育方面不断加大投入，鼓励学生主修科学、技术、工程和数学，培养其科技理工素养。

简介：摘要：目前，在高中通用技术教学中，以跨学科整合为核心，通过问题学习、项目学习以及工程设计等方式提升学生综合素养的STEM教育模式备受关注。高中通用技术课程具有实践性强、综合度高、兼顾工程与系统思想的特点，是发展STEM教育的良好平台。基于此，本位就立足STEM理念，进而实现通用技术课程教学的有效进行，学生在学习过程中能够通过思维的探究和工程设计实践，解决实际问题，落实学科核心素养。

简介：摘要：目前，在高中通用技术教学中，以跨学科整合为核心，通过问题学习、项目学习以及工程设计等方式提升学生综合素养的STEM教育模式备受关注。高中通用技术课程具有实践性强、综合度高、兼顾工程与系统思想的特点，是发展STEM教育的良好平台。基于此，本位就立足STEM理念，进而实现通用技术课程教学的有效进行，学生在学习过程中能够通过思维的探究和工程设计实践，解决实际问题，落实学科核心素养。

简介：摘要：伴随着当前我国教育事业高速发展的趋势，对于教育者而言，既要注重对学生开展知识教育，更为重要的是要培养起学生良好的学习习惯，在初中教育阶段当中，物理学科是一门重要的基础性学科。可有效地培养学生的创新思维能力与探究学习能力。在当前科技高速发展的背景下，整个社会需要更多的综合型创新人才，在现今国际教育领域当中，STEM 教育作为一种新兴的教育模式，我国教育界也对这一教育模式进行了持续性地关注，而在我国教育改革的发展前提下，当前初中物理的教学方式方法，也应与时俱进地进行改进与完善，围绕提升学生自主探究学习水平这一重要的教学目标，在物理课堂教学当中，有效地渗透STEM教学理念，以此来培养学生的核心素养。使学生在学习掌握物理知识的基础上，充分激发学生的物理学习兴趣。本文以初中物理课堂教学作为研究对象，深入研究了在当前的初中物理教学中，如何有效地应用 STEM 教育理念，并据此提出一些合理化的意见与建议。

简介：摘要：在政府大力推动生态文明的政策之下，很多学校开始响应“绿水青山就是金山银山”的政策号令，我们既要发展经济，建成小康社会，又不能以环境毁坏为代价。因而，对于现阶段当中水资源治理问题，就需要采取多样化的方式进行有效的解决。因而，本文以“污水净化”为研究对象，对于“如何开发污水净化STEM课程”进行深入探究。

简介：摘要：随着信息化时代到来，社会对信息技术人才的需求愈发迫切，初中教育中的信息技术课程的开展也随之成为社会各界重点关注的对象。但由于我国的信息技术教育历史相对西方国家较短，在许多地方还存在有待改进的地方，所以教学效率相对较低。而在STEAM 的教育理念融入后，这一教育窘境将会被改变，信息技术教育将能够更好地满足学生的实际需求。基于此，本文将对基于stem的初中信息技术教学探究展开研究。

简介：【摘要】自主学习能力是小学生必须具备的一种学习能力。它也是学生适应现代学习、提高自身素质的有力基础全球性的小学教师要从学生的学习特点出发，抓住数学教学的重点，注重建设学生的学习自主性。

简介：摘要：随着人类科学技术的不断进步，社会对拥有创新思维、持续学习能力的创新型人才的需求越来越大。在学校开展STEM教育，能够提升学校的整体竞争力，也能为社会培养更多高素质人才。

简介：摘要：随着教育教学的不断向前发展，寻求最佳的教学路径已经成为各个学校在教学创新中的探索方向，STEM教育理念在与小学科学教学相融合的过程中，不断能够让学生脱离传统教学空间，形成创新发展趋势，在各学科融合中学生综合性解决问题，科学学科注重学生科学思维的形成，不断能够产生科学探索意识，在教师的不断鼓励下以及多元情境下，加速学生的全面发展。教师在教学实践中应当深刻理解STEM教育与小学科学之间的关系，取得最佳的教学效果，让学生形成科学合理的创新发展意识，在实践探索和自主发展中培养学生的科学素养。

简介：AbstractIntroduction:Langerhans cell histiocytosis (LCH), the most common histiocytic disorder, characterized by the abnormal over production of histiocytes that tend to infiltrate single or multiple organ systems leading to significant tissue damage.Here we report a case of an adult patient who was diagnosed with LCH presenting as multisystem involvement.Case presentation:We describe a 23-year-old man suffering from central diabetes insipidus, "hemorrhoids", progressive hearing loss and a surge in weight. Physical examination revealed lesion involvement of the skin and mucous membranes, including the perianal area, gingiva, and external auditory canal. He was diagnosed as LCH, who achieved remission following a chemotherapy regimen.Discussion:LCH is common in children, but it is not surprising to see it in adults. The clinical manifestations of LCH are highly variable and may involve multiple organs and systems. While, skin involvement is the most obvious symptom, and dermatologists should be familiar with it. Chemotherapy is the first-line treatment for multisystem or multifocal single system adult LCH.Conclusion:Characteristic features of LCH involving the perianal area was described in this case which helped the dermatologist to make quick judgments. We also emphasize that a global concept should be established confronting with a patient with multiple complaints.

简介：AbstractObjective:To clarify whether the serum squamous cell carcinoma antigen (SCCA) levels of patients with inverted papilloma (IP) are different from patients with nasal polyps (NP) and rhinitis.Materials and methods:Serum SCCA levels were measured in 30 patients with IP and 30 patients with NP at one day before surgery and seven days after surgery and measured in 28 patients with rhinitis.Results:Elevated serum SCCA levels (>1.5 ng/ml) were found in 80.0% of patients in the IP group, 6.7% of patients in the NP group and 14.3% of patients in the rhinitis group, which was a significant difference. The medians of serum SCCA levels in the IP, NP and rhinitis groups were 3.9, 0.8 and 1.1 ng/ml, respectively, which was a significant difference. The SCCA level in IP group was not significantly correlated according to Krouse Staging. There was a significant difference in serum SCCA levels between the pre- and postoperative stages in the IP group, at 3.9 and 0.8 ng/ml, respectively, while in the NP group the levels were 0.8 and 1.0 ng/ml, not significantly different. With regard to the IP diagnosis in the IP and NP group based on the SCCA level (>1.5 ng/ml), sensitivity and specificity was 80.0% and 93.3%, respectively.Conclusions:The serum SCCA level in patients with IP was elevated and then it decreased after surgery. This was different from NP and rhinitis patients who mostly had normal levels, which did not change.

简介：AbstractIntroduction:Erosive pustular dermatosis of the scalp (EPDS) is an uncommon condition with unknown etiology. The clinical exclusive diagnosis needs to be differentiated from similar diseases.Here, we present a case of EPDS after surgical treatment of scalp squamous cell carcinoma.Case presentation:A 68-year-old woman presented with an eight-month history of a chronic scalp eruption. She had been diagnosed as squamous cell carcinoma by biopsy nine months ago, and had been treated by surgical excision and skin grafting. One month later, she was referred for evaluation of the newly enlarged lesion which was observed at the skin grafting site. She was diagnosed of EPDS based on characteristics of lesions, clinicopathological findings and laboratory data. The condition had clinically improved with systemic steroid therapy and topical tacrolimus for two weeks. Relapses occurred after complete withdrawal of both treatments. After repeating the above therapy and applying topical tacrolimus as maintenance therapy, the condition was well controlled at the one-year follow-up.Discussion:EPDS is an uncommon inflammatory dermatosis with main incidence rate of elderly patients and female predominance. The diagnosis of EPDS cant be made only by histopathological examination, which is helpful for differential diagnosis. Microbiological investigations commonly remain negative. For the high risk of relapse, it is important for clinicians to be aware of maintenance treatment and a long-term management.Conclusion:It should be recognized by clinicians that EPDS is an uncommon and relapse disease, leading to serious cosmetic problems. The treatment lacks evidence-based medicine data, clinician should choose the appropriate therapy according to the condition of patients.

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简介：摘要：所谓stem教育，就是将科学（Science）、技术（Technology）、工程（Engineering）、数学（Mathematics)几门学科，融合到一起进行跨学科综合性素质教育。stem教育以学生的实际生活、未来发展作为学习的出发点，注重实践和培养学生的动手能力。学生要将所学知识进行综合化运用，通过仔细分析，解决现实问题，以达到学以致用，从而提高学生综合素质水平的目的。本文以stem教育在偏远落后地区的实践与探索为主题进行探讨，希望可以为相关的教育工作者提供一定的帮助。

简介：AbstractSkeletal muscle plays an essential role in generating the mechanical force necessary to support the movement of our body and daily exercise. Compared with cardiac and smooth muscle, in mammals, skeletal muscle exhibits remarkable regenerative capacity in response to damage. Muscle stem cells, also known as satellite cells, directly contribute to regeneration. Here, we review primary and secondary myogenesis processes with a focus on muscle stem cells, as well as the function and regulation of muscle stem cells in adult muscle regeneration in mammals.

简介：摘要：STEM教育是一种新的教育理念，相比于应试教育，STEM教育更注重多元化结合实践教育，打破传统教学课堂，培养学生的科学素养，技术素养，工程素养，数学素养。比起现代的填鸭式教学，提升了的是学生长久的学习能力技巧，终身受用。

简介：摘要：高中化学是一门实践性比较强的课程，而且知识点比较多，具有一定的难度。为了方便学生更好的学习化学知识，引入STEM教育理念，可以把科学、技术、工程和数学等各方面内容整合在一起，系统梳理化学知识点，使学生更好的理解化学知识，提高学习效率，本文对此进行了相关探讨。

简介：摘要:随着我国科学技术的不断改革和创新，在小学教育的发展当中，也需要积极的去采用一些先进的教育方式来提高教学的效率和质量，而STEM的教育方式能够在一定程度上去增加学科的特色，让学生们在实际的学习过程当中获得更多的知识。本篇文章就是以如何实现STEM教育与小学科学的融合为中心而展开讨论和分析的。

简介：摘要：在小学教学阶段，将STEM教育与小学科学有效融合，不仅有助于培养学生的科学创新意识，还有助于完善学生的科学核心素养，促进学生全面的发展。为此，本文主要探究将STEM教育与小学科学有效融合的教学策略，希望能够为广大小学科学教师提供思路和参考。

简介：AbstractChemotherapy is often used for female malignancies, but it can increase the risk of premature ovarian failure in women of reproductive age through different mechanisms. Therefore, how to protect ovarian function and preserve fertility has attracted great attention of oncologists and gynecologists. Recently, umbilical cord mesenchymal stem cells (UCMSCs) have been extensively studied in the field of regenerative medicine. Compared with mesenchymal stem cells (MSCs) from other sources, UCMSCs have a broader application potential due to their properties of lower immunogenicity, fewer ethical issues, and non-invasive collection. Paracrine is one of the most important therapeutic mechanisms of UCMSCs, which can exert anti-inflammatory, anti-fibrosis, anti-oxidative stress, immune regulation, and other therapeutic effects. Studies in animal models have shown that UCMSCs can restore ovarian function after chemotherapy injury. However, most of the relevant researches are still in the preclinical stage. In this article, the mechanism of chemotherapy-induced ovarian failure will be overviewed, and the clinical application potential of UCMSCs in chemotherapeutic ovarian injury will be discussed.