简介:FriendlyCooperationBasedonFullTrust──CAFIUDelegationVisitedGermanyByWuXingtang吴学谦会长率交协代表团访德CAFIUdelegation,headedbyPresidentW...
简介:Thisarticleelaboratestheviewpointthathowtostrengthenqualitymanagementofcasetogivefullplaytoitsvalue,thepointsthattheauthorurgedareinfollowingaspects,includingraisingqualityconsciousnessofcasewriting,upgradingthewritingqualityofcase,payingattentiontothevalueofcaseandensuringthequalityofcase.1.Trainingdoctor's“basicskill”.2.Trainingsystemofdoctor,a.Inthefirstmonthaftercheck-in,arrangetwolecturesaboutwritingofcasetounifytherequirementandinformthemhowtowriteit.b.Givethemthewritingstandardofanamnesis,whichtheycanrefertowhenwriting.3.Thesystemthatthedirectorsspot-checktheanamnesis.TheAmericanqaulityadministrativepower,world-famousDoctorMilanprophesiedthat“21centuryiscenturyofquality”,havingentered21century,factsalsofurtherprovedthefacticityofthisprophesy.Thenewerainwhichthequalityissupreme,qualitydirectlyinfluenceswhetherthecasecanfullyplayitsvalue.
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简介:Theprinciplesandfeaturesofthepressure-liquidometerusingopticalfibersensor,whichissuitabletouseindangerousareas,aredescribed.Theinstrumentiseapeciallysuitableforautomaticdetectingofpressureandliquidlevelindangerousaslargesacleoiltanker,caveoiltanker,civicliquid-gastankerandsoon.
简介:Thispaperdiscussesthedefinitionandpropertiesofmultivaluedsymmetricfunctions,pointsoutthatamultivaluedsymmetricfunctioncanbedecomposedaccordingtothevalueofthefunctionj.ThesubfunctionLjcorrespondingtojmustbeasymmetricfunction,anditmaybeexpressedasthesumofproductsformofdegeneratedmultivaluedfundamentalsymmetricfunctions.Basedonthisconsideration,thecircuitrealizationforthemultivaluedsymmetricfunctionsbasedonfulladdersisproposed.
简介:Currentliteraturesassumethataconsumer’swillingtopay(WTP)forabundleisequaltothesumofhisorherseparatereservationpricesforthecomponentgoodsandconcludesthatmixedbundlingissuperiortopurecomponentsinamonopolymarket.However,fullmixedbundlingisadiscountconductinordertoattractmoreconsumers,andthepriceofthebundlemustbelowerthanthesumofthepricesoftwoproducts,whichmustbeconsideredinaconsumers’WTPforthebundle.Then,ifconsumers’reservationpricesareheterogeneousandsubjecttotheuniformdistribution,wecandrawoppositeconclusions:FullmixedbundlingisdisadvantageoustofirmswhenStackelbergpricing.Theprofitunderfullmixedbundlingislessthanthatunderpurecomponents.
简介:AccordingtoZhejiangDaily,ZhejiangProvincehasissuedaseriesofpoliciesincludingbasiclivingallowances,healthcare,education,housing,administrationofjustice,assistanceforthedisabled,temporaryrelief,etc.Fullcoverageofsocialassistancehasbeenbasicallyattainedforpeoplewithfinancialdifficultiesanddifficult
简介:在一台接近音速的离心的压缩机发展的流动的完整的体环模拟在二个稳定的操作点(山峰效率和近的巨浪)并且在路径期间被执行澎湃。以稳定的条件,流动地性质被比较用落后途径以前执行了的一个阶段与试验性的数据和数字模拟分析。关于舞台外套表演,一个优秀协议在数字结果之间被获得(两个与时间落后途径和完整体环的计算)并且实验。从完整体环的模拟,在到巨浪的从山峰效率的流动模式的变化被发现非常类似于用时间从模拟获得了那落后途径。特别地,如果操作的点是稳定的,流动证明是chorochronic.The完整体环模拟在法律在数字领域的出口使用了的throttle在一个唯一的小面值硬币以后被继续。集体流动,压力比率和效率然后显著地更加掉时间进步。模拟变得不稳定并且很好在进行之中的巨浪开始。澎湃的路径被发现由于根据从chorochronic模拟和实验得出的结论的更弥漫的翼的吸方面上的边界层分离的增大。但是当时间进行,流动失去它的chorochronic特性。在约7%转子速度点旋转的货摊房间在约5条革命开发并且导致巨浪。
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简介:我们调查了与不同联合的杂质总数做的水泥的机械性质。而且,机制被测试的版本,CT,和坚硬探索。结果显示出那充分染色锈并且出现染色锈的沙岩聚集当沙岩总数在水泥的最终的紧张上有更多明显的影响时,在水泥的压缩力量上有重要不利影响。具体快克是更多对敏感沿着表面膨胀并且界面的转变微坚硬不同总数的地区在是的减少的趋势被评价沙岩,板岩,SR沙岩,大理石,和FR沙岩。长像针的ettringite水晶和Ca的强壮的优先的生长趋势的簇生长(哦)2晶体将导致水泥的地区范围分别地与充分染色锈的沙岩和云石总数做了的更宽的界面的转变。因此,杂质总数内容应该严格地在总数选择期间被控制。
简介:利用PCR以实验室构建的原核重组表达质粒pProEX-OCIF为模板扩增得到N末端融合有6×His标签和rTEV蛋白酶识别序列的人破骨细胞形成抑制因子(OsteoclastogenesisInhibitoryFactor,简称OCIF)结构域D1~D6(简称OCIFm)编码基因片段;将其与pMD18-T连接,转化大肠杆菌TOP10,筛选得到阳性重组质粒pMD18-OCIFm,双酶切重组克隆质粒pMD18-OCIFm得到OCIFm基因片段;将其定向插入甲醇营养型酵母分泌表达载体pPIC9中,构建获得重组表达质粒pPIC9-OCIFm.测序验证后,以限制性内切酶SalⅠ线化,电穿孔转化酵母宿主菌GS115.筛选得到阳性表达菌株后,甲醇诱导表达4d,SDS-PAGE和Westernblot对表达情况进行分析和确认.所获得的OCIFm基因片段在甲醇营养型酵母中表达量占菌体总蛋白的30%以上.利用Ni-NTA树脂对表达产物进行一步亲和层析纯化.活性测定表明纯化的表达产物可诱导体外培养的成熟破骨细胞样细胞的凋亡.表达产物的生物学活性较利用原核表达系统明显提高.
简介:摘要:本文探讨了高效节能的D1/D2类压力容器热处理工艺的优化和应用。通过引入新型感应加热设备和智能控制系统,改进了传统热处理工艺中存在的效率低、能耗高的问题。优化后的工艺流程包括精细调整加热温度、保温时间和冷却速率等关键参数,实现了温度的均匀分布和过程的稳定可控。在实际应用中,改进后的工艺显著缩短了热处理周期,提高了生产效率和能源利用率,产品的拉伸强度和冲击韧性分别提高了约15%和20%。次品率从3%下降到不足1%,产品质量的一致性和客户满意度显著提升。本文的研究为D1/D2类压力容器的生产提供了有效的技术支持和参考,具有重要的应用价值和推广前景。
简介:摘要目的探讨念珠菌细胞壁成分(1-3)-β-D葡聚糖检测的体外影响因素;方法实验组将白色假丝酵母菌用正常血浆、无热原蒸馏水、0.9%的生理盐水、0.02%两性霉素B生理盐水和0.75%氟康唑生理盐水稀释为0.5麦氏单位(含白色念珠菌1X107CFU/ml),对照组将上述各液稀释100倍,采用免疫沉淀试验(G试验)检测其10次(1-3)-β-D葡聚糖含量,并进行体外培养,以此探讨生理盐水、抗真菌药物对(1-3)-β-D葡聚糖体外检测的影响;结果实验组中,正常血浆葡聚糖含量为(92.5土14.2)ug/l,蒸馏水组含量为(94.5土15.2)ug/l,生理盐水组含量为为(93.6土14.8)ug/l,两性霉素B组含量为(95.5土16.2)ug/l,氟康唑组(97.3土16.8)ug/l,经统计检验组内结果间无显著性差异(P>0.05)。对照组中正常血浆含量为(6.8土2.7)ug/l,蒸馏水组含量为(6.1土2.4)ug/l,生理盐水组含量为为(7.3土2.0)ug/l,两性霉素B含量为(6.8土2.5)ug/l,氟康唑组(6.7土2.8)ug/l,经统计检验组内间结果无显著性差异(P>0.05)。实验组与对照组比较有显著差异(p<0.001)。结论体外真菌细胞壁(1-3)-β-D葡聚糖含量变化与液体介质的无关,与真菌治疗药物无关,与念珠菌数量密切相关。
简介:Cytarabine(1-β-D-arabinofuranosylcytosine,Ara-C),isolatedfromaCaribbeanspongespeciesTethyacrypta,isthefirstantitumordrugfromamarineresource.In1980,theUSFoodandDrugAdministrationapprovedthisdrugforthetreatmentofdifferenttypesofleukemia.Thisdrughasashortplasmahalf-life,lowstability,limitedbioavailability,andseveresideeffects.Toimprovestabilityandbioavailability,wesynthesizedninenovelderivativesbyblockingthecytarabinemetabolicsitesandimprovinglipophilicity.ThecLogPvaluesofthenewlysynthesizedcompoundswerecalculated.Allthesynthesizedcompoundsweremorelipophilicthancytarabine,resultinginmembranepermeabilityandbioavailabilityimprovement.TheantitumoractivitiesagainstleukemiacelllineHL-60wereevaluatedbyusingtheMTTassay.ThebioassayresultsrevealedthattheIC50valuesofcompounds5,8and9were0.080,0.090and0.057μmolL-1,respectively,whichwassimilarwiththatofcytarabine(0.056μmolL-1).Incomparison,compound4withaphosphategroupatO5’wasinactive.Becausephosphoesterbondsareeasilyhydrolyzedbyalkalinephosphataseandarecommonlyusedinproducingprodrugstrategies,compound4mightalsobemetabolizedinvivoandgeneratecompound3orevencytarabinethroughamulti-stepreaction.Thus,compound4mightbeapromisingcompoundtobedevelopedasaprodrug.